YRC Public Data Repository - Protein Structure Prediction

Protein:	DAL4
Organism:	Saccharomyces cerevisiae
Length:	635 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAL4.

Description	E-value	Query Range	Subject Range
gi\|190408808 - gi\|190408808\|gb\|EDV12073.1\| uracil permease [Saccharomyces cerevisiae RM11-1a] gi\|207347785 - gi\|207347785\|gb\|EDZ73852.1\| YBR021Wp-like protein [Saccharomyces cerevisiae AWRI1631] FUR4 - Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels ... gi\|151946414 - gi\|151946414\|gb\|EDN64636.1\| uracil permease [Saccharomyces cerevisiae YJM789] FUR4_YEAST - Uracil permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUR4 PE=3 SV=2	641.0	[0..33]	[632..32]
gi\|52352511 - gi\|52352511\|gb\|AAU43748.1\| FUR4 [Saccharomyces kudriavzevii IFO 1802]	620.0	[0..33]	[632..32]
gi\|50285469, gi\|... - gi\|50285469\|ref\|XP_445163.1\| unnamed protein product [Candida glabrata], gi\|49524466\|emb\|CAG58063.1\|... gi\|49524466 - gi\|49524466\|emb\|CAG58063.1\| unnamed protein product [Candida glabrata]	585.0	[0..39]	[632..61]
gi\|49642354 - gi\|49642354\|emb\|CAH00316.1\| KLLA0D03454p [Kluyveromyces lactis] gi\|50306493, gi\|... - gi\|50306493\|ref\|XP_453220.1\| unnamed protein product [Kluyveromyces lactis], gi\|49642354\|emb\|CAH0031...	514.0	[0..39]	[621..52]
YEME_SCHPO - Uncharacterized permease C29B12.14c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29... SPAC29B12.14c - purine transporter	510.0	[0..71]	[630..14]
gi\|11278826, gi\|... - gi\|1420854\|emb\|CAA67256.1\| uracil permease [Schizosaccharomyces pombe], pir\|\|T43295 uracil transport...	485.0	[0..54]	[620..4]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANDALSAIF SNPSRKGVQP STSIVSYTNN EDDIIDVENG KFNKNKNINT NVYVDNSSIE  60
   61 ESEVVPLPET KSIWSKIYYD FIVLDKTTLN VSLKESFLYN RDLKPV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.99
Match:	1sa1E
Description:	TUBULIN-PODOPHYLLOTOXIN: STATHMIN-LIKE DOMAIN COMPLEX
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [107-635]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEERRCWSWF NYLYFWLADC FNINTWQIAG TGLQLGLNWW QCWLTVWIGY TFAGIFVVLN  60
   61 SRFGSAYHLS FPITVRASFG IFFSMWPIIN RVVMAIVWYA VQAWLGATPV ALMLKSIFGK 120
  121 NLEDRIPNHF GSPNSTTFEF MCFFIFWVVS IPFVLVAPHK IRHLFTVKAA LIPFAAFGFL 180
  181 IWALKKSHGK IELGTLNDYS PHGSEFSWIF VRSLMACVAN FAALIINAPD FGRFAKNPQA 240
  241 SLWPQLVAIP LFFAITCLIG IIVTAAGYHL YGVNYWSPLD VLGQFLETTY TRGTRAGVFL 300
  301 ISFVFALAQL GTNISANSLA CGADMTALFP RYINIRRGSL FCVAMALCIC PWNLMASSSK 360
  361 FTSALGAYAI FLSSIAGVIC ADYFVVRRGY VKLTHLFLAQ KGSFYMFGNK FGANWRAFVA 420
  421 YICGIAPNLP GFIGDVGAPK ITVSEGAMRL YYLGYPVGFF ISAVIYLILC YFFPVPGTPV 480
  481 TNFLTEKGWF QRWAYVEDFE QDWKNELRRD DLCDDTVSIY DGTEEKIVY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.31
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits