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View Structure Prediction Details

Protein: AIM21
Organism: Saccharomyces cerevisiae
Length: 679 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIM21.

Description E-value Query
Range
Subject
Range
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
7.0E-56 [2..589] [782..1366]
NFH_MOUSE - (P19246) Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polype...
2.0E-54 [3..584] [496..1087]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-54 [3..581] [492..1069]
NFH_RAT - Neurofilament heavy polypeptide OS=Rattus norvegicus GN=Nefh PE=1 SV=4
1.0E-52 [3..581] [263..828]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
2.0E-50 [228..664] [535..996]

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Predicted Domain #1
Region A:
Residues: [1-17]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSEVTPKVP ERPSRRK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [242-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESDDKAEKFT KHPESSLEEL QKHQEQQEEK IFQNPTDEES TTSLNEKQEG KDNMEVNSQP  60
   61 QGPSDTETVI AATSSNVPS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.0
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [18-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSELFPLSGS ESGDIKANSE PPTPAGTPNV PTRRPILKAK TMTSFESGMD QESLPKVPLQ  60
   61 RPVRRSTTEE LNN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.0
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [91-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMNNTSKELE EIESLISKHN IHNVSRKKSP TSVEEGKVAA IHQNGQRSAS DNKTSTNPSP  60
   61 LEKNEHEGAE GNESAISPS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.0
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [170-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLVNKSNNEV TEHSDSEDLT EKQKVHAALD NEAGDRSHFE EKLIPGDMKV QVDVSKDVEE  60
   61 GSLNALPPSG IT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.0
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [321-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIASEEENDV PVIPRSRPKK DFEAHVQKEE LPNTQEKRVS EECDSTLIST EEESKIPKIP  60
   61 SERPKRRAPP PVPKKPSSRI AAFQEMLQKQ QQQDLHNNGN SSATTASADI AKKHTDSSIT 120
  121 SDTTKADFTS KLNGLFALPG MVNPGQLPPS LEKKLSSPDT ESKLGPQDQS QAKTGPLGGT 180
  181 RRG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.9
Match: 1jhnA
Description: Calnexin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [504-591]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGPRGRKLPS KVASVEKIEE DDNTNKIEIF NNWNVSSSFS KEKVLIDTTP GEQAERALDE  60
   61 KSKSIPEEQR EQSPNKMEAA LCPFELDE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.75
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [592-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEKLPANAES DPLSQLPQTN AVGNRKAISE ESLSPSEAIA NRDQNDTTEI QEQQMEDQME  60
   61 VDMERELSGG YEDVDSALHS EEASFHSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.306 a.4.5 "Winged helix" DNA-binding domain
View Download 0.335 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.429 a.4.12 TrpR-like
View Download 0.285 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.424 a.46.1 Methionine synthase domain
View Download 0.277 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.250 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.244 a.4.5 "Winged helix" DNA-binding domain
View Download 0.237 a.77.1 DEATH domain
View Download 0.206 a.36.1 Signal peptide-binding domain
View Download 0.202 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle