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View Structure Prediction Details

Protein: NIT1
Organism: Saccharomyces cerevisiae
Length: 199 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIT1.

Description E-value Query
Range
Subject
Range
NRL3_ARATH - Nitrilase 3 OS=Arabidopsis thaliana GN=NIT3 PE=1 SV=1
3.0E-52 [2..195] [23..212]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-52 [2..196] [23..213]
NRL4A_TOBAC - Bifunctional nitrilase/nitrile hydratase NIT4A OS=Nicotiana tabacum GN=NIT4A PE=2 SV=1
9.0E-50 [3..199] [28..220]

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Predicted Domain #1
Region A:
Residues: [1-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKHIVAALQ IGSCPGSTKD TLKKILSYEK EIKESGAKLV VIPEATLGGY PKGSNFGVYL  60
   61 GYRLQEGREE YAKYLAEAIE IGNGEKYPEI SQLCALSKAT DASLCVGCIE RDGTTLYCTM 120
  121 VYIDPKDGYV GKHRKLMPTA GERLIWGQGD GSTLPVVDTA AGKIGGAICW ENMMPLLRYA 180
  181 MYKKGVEIWC APTVDARPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.39794
Match: 1f89A_
Description: hypothetical protein yl85
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.877995814635227 bayes_pls_golite062009
hydrolase activity 0.752213402780482 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.0225695859908339 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle