YRC Public Data Repository - Protein Structure Prediction

Protein:	PAN6
Organism:	Saccharomyces cerevisiae
Length:	345 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAN6.

Description	E-value	Query Range	Subject Range
PANC_THEMA - Pantothenate synthetase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=... PANC_THEMA - Pantothenate synthetase OS=Thermotoga maritima GN=panC PE=1 SV=1	0.0	[37..345]	[1..279]
PANC_THENE - Pantothenate synthetase OS=Thermotoga neapolitana GN=panC PE=3 SV=1	0.0	[37..345]	[1..279]
PANC1_BRADU - Pantothenate synthetase 1 OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 1479... PANC1_BRAJA, PAN... - Pantoate--beta-alanine ligase - Bradyrhizobium japonicum, Pantothenate synthetase 1 OS=Bradyrhizobiu...	0.0	[37..345]	[1..278]
PANC_ECO5E - Pantothenate synthetase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=panC PE=3 SV=1 gi\|217324286, gi... - gi\|217324286\|ref\|ZP_03440370.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. TW14588... gi\|13359593, gi\|... - gi\|15829391\|ref\|NP_308164.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. Sakai], gi... gi\|195938185 - gi\|195938185\|ref\|ZP_03083567.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4024] gi\|208805724, gi... - gi\|208805724\|ref\|ZP_03248061.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4206]... gi\|208813527, gi... - gi\|208813527\|ref\|ZP_03254856.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4045]... gi\|208741373, gi... - gi\|208821250\|ref\|ZP_03261570.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4042]... gi\|168776844, gi... - gi\|187767832\|gb\|EDU31676.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4196], gi... gi\|189000425, gi... - gi\|189000425\|gb\|EDU69411.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4076], gi... gi\|15799817, gi\|... - gi\|15799817\|ref\|NP_285829.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 EDL933], gi\|125... gi\|189371078, gi... - gi\|189371078\|gb\|EDU89494.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|25323773, gi\|... - pir\|\|A85497 pantothenate synthetase [imported] - Escherichia coli (strain O157:H7, substrain EDL933... gi\|189376401, gi... - gi\|189376401\|gb\|EDU94817.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|188013709, gi... - gi\|188013709\|gb\|EDU51831.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4113], gi... gi\|189357079, gi... - gi\|189357079\|gb\|EDU75498.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4401], gi... gi\|168764723, gi... - gi\|189365335\|gb\|EDU83751.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4501], gi... gi\|189360667, gi... - gi\|189360667\|gb\|EDU79086.1\| pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4486], gi... PANC_ECO57 - Pantothenate synthetase OS=Escherichia coli O157:H7 GN=panC PE=3 SV=1 gi\|254791268, gi... - gi\|254791268\|ref\|YP_003076105.1\| pantothenate synthetase [Escherichia coli O157:H7 str. TW14359], gi...	1.0E-99	[43..345]	[4..280]
gi\|75512008, gi\|... - gi\|75512008\|ref\|ZP_00734603.1\| COG0414: Panthothenate synthetase [Escherichia coli 53638], gi\|188493... gi\|85674348, gi\|... - gi\|89107014\|ref\|AP_000794.1\| pantothenate synthetase [Escherichia coli str. K-12 substr. W3110], gi\|... gi\|83569716, gi\|... - gi\|83569716\|ref\|ZP_00921166.1\| COG0414: Panthothenate synthetase [Shigella dysenteriae 1012], gi\|194... EG11746 - pantothenate synthetase / Pantothenate synthase, dimeric PANC_ECO24 - Pantothenate synthetase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=panC PE=3 SV=1 PANC_ECODH - Pantothenate synthetase OS=Escherichia coli (strain K12 / DH10B) GN=panC PE=3 SV=1 PANC_ECOSE - Pantothenate synthetase OS=Escherichia coli (strain SE11) GN=panC PE=3 SV=1 PANC_ECO8A - Pantothenate synthetase OS=Escherichia coli O8 (strain IAI1) GN=panC PE=3 SV=1 gi\|191166378, gi... - gi\|75230502\|ref\|ZP_00716983.1\| COG0414: Panthothenate synthetase [Escherichia coli B7A], gi\|19116637... PANC_ECO55 - Pantothenate synthetase OS=Escherichia coli (strain 55989 / EAEC) GN=panC PE=3 SV=1 gi\|193063209, gi... - gi\|75258874\|ref\|ZP_00730264.1\| COG0414: Panthothenate synthetase [Escherichia coli E22], gi\|19306320... gi\|226840657, gi... - gi\|254037551\|ref\|ZP_04871628.1\| pantothenate synthetase [Escherichia sp. 1_1_43], gi\|226840657\|gb\|EE... PANC_ECOHS - Pantothenate synthetase OS=Escherichia coli O9:H4 (strain HS) GN=panC PE=3 SV=1 PANC_ECOBW - Pantothenate synthetase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=panC PE=3 SV=1 gi\|75210460, gi\|... - gi\|75210460\|ref\|ZP_00710611.1\| COG0414: Panthothenate synthetase [Escherichia coli B171], gi\|1944282... PANC_ECOLI - Pantoate--beta-alanine ligase (EC 6.3.2.1) (Pantothenate synthetase) (Pantoate-activating enzyme) - ... EG11746 - pantothenate synthetase / Pantothenate synthase, dimeric	2.0E-99	[43..345]	[4..280]
PANC_CLOAB - Pantothenate synthetase OS=Clostridium acetobutylicum GN=panC PE=3 SV=1 PANC_CLOAB - Pantothenate synthetase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 57...	2.0E-99	[37..342]	[1..276]
gi\|165922293, gi... - gi\|165925681\|ref\|ZP_02221513.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Orientalis str... gi\|165990892, gi... - gi\|166009985\|ref\|ZP_02230883.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Antiqua str. E... gi\|165915333, gi... - gi\|165936684\|ref\|ZP_02225251.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Orientalis str... gi\|167052067, gi... - gi\|167399563\|ref\|ZP_02305087.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Antiqua str. U... gi\|166214070, gi... - gi\|166214070\|ref\|ZP_02240105.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Antiqua str. B... gi\|167423615, gi... - gi\|167423615\|ref\|ZP_02315368.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Mediaevalis st... gi\|166961435, gi... - gi\|167420629\|ref\|ZP_02312382.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Orientalis str... PANC_YERPA - Pantothenate synthetase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=panC PE=3 SV=1 gi\|153997555, gi... - gi\|153997555\|ref\|ZP_02022655.1\| pantoate--beta-alanine ligase [Yersinia pestis CA88-4125], gi\|149289... PANC_YERPN - Pantothenate synthetase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=panC PE=3 SV=1 PANC_YERPP - Pantothenate synthetase OS=Yersinia pestis (strain Pestoides F) GN=panC PE=3 SV=1 gi\|45440142, gi\|... - gi\|45440142\|ref\|NP_991681.1\| pantoate--beta-alanine ligase [Yersinia pestis biovar Microtus str. 910... gi\|21957512, gi\|... - gi\|22124698\|ref\|NP_668121.1\| pantoate--beta-alanine ligase [Yersinia pestis KIM], gi\|21957512\|gb\|AAM... gi\|218930419, gi... - gi\|218930419\|ref\|YP_002348294.1\| pantoate--beta-alanine ligase [Yersinia pestis CO92], gi\|16123551\|r... PANC_YERPE - Pantothenate synthetase OS=Yersinia pestis GN=panC PE=1 SV=1 gi\|167469891 - gi\|167469891\|ref\|ZP_02334595.1\| pantoate--beta-alanine ligase [Yersinia pestis FV-1] gi\|229839040, gi... - gi\|229839040\|ref\|ZP_04459199.1\| pantothenate synthetase [Yersinia pestis biovar Orientalis str. PEXU... gi\|229896519, gi... - gi\|229896519\|ref\|ZP_04511687.1\| pantothenate synthetase [Yersinia pestis Pestoides A], gi\|229700593\|... gi\|229899605, gi... - gi\|229899605\|ref\|ZP_04514746.1\| pantothenate synthetase [Yersinia pestis biovar Orientalis str. Indi... PANC_YERPG - Pantothenate synthetase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=panC PE=3 SV=1	4.0E-99	[43..345]	[4..280]
PANC_PSEAB - Pantothenate synthetase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=panC PE=3 SV=1 PANC_PSEAE - Pantothenate synthetase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 122... gi\|254238533, gi... - gi\|84317389\|ref\|ZP_00965837.1\| COG0414: Panthothenate synthetase [Pseudomonas aeruginosa C3719], gi\|... gi\|107103829 - gi\|107103829\|ref\|ZP_01367747.1\| hypothetical protein PaerPA_01004900 [Pseudomonas aeruginosa PACS2] PANC_PSEAE - Pantothenate synthetase OS=Pseudomonas aeruginosa GN=panC PE=3 SV=1	6.0E-99	[41..345]	[2..280]
PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus (strain VF5) GN=panC PE=3 SV=1 PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus GN=panC PE=3 SV=1	9.0E-99	[39..342]	[4..277]
PANC_NEIMA - Pantothenate synthetase OS=Neisseria meningitidis serogroup A GN=panC PE=3 SV=1 gi\|11279933 - pir\|\|F81874 probable pantoate-beta-alanine ligase (EC 6.3.2.1) NMA1089 [imported] - Neisseria mening... PANC_NEIMA - Pantothenate synthetase OS=Neisseria meningitidis serogroup A / serotype 4A (strain Z2491) GN=panC P...	2.0E-98	[37..345]	[1..275]

Back

Predicted Domain #1

Region A:
Residues: [1-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNISRCSVHI YVYKKWCVLI LHCFIQVFIL HIHIELMKIF HTVEEVVQWR TQELRETRFR  60
   61 ETIGFVPTMG CLHSGHASLI SQSVKENTYT VVSIFVNPSQ FAPTEDLDNY PRTLPDDIKL 120
  121 LESLKVDVLF APNAHVMYPQ GIPLDIEEQK GPFVSVLGLS EKLEGKTRPN FFRGVATVVT 180
  181 KLFNIVMADV AYFGQKDIQQ FIVLQCMVDE LFVNTRLQMM PI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	561.9691
Match:	1ihoA_
Description:	Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [223-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRNNNGLALS SRNKYLCPES LKISENLYRG LKAAENAIRR LAPGGRLSRS EIIDTVTQIW  60
   61 APYVDSHDFK IDYVSLADFK TLDELSDVEN TSEQQPIVIS CAVYVTDREK PDTVVRLIDN 120
  121 IVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	561.9691
Match:	1ihoA_
Description:	Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits