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View Structure Prediction Details

Protein: AYR1
Organism: Saccharomyces cerevisiae
Length: 297 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AYR1.

Description E-value Query
Range
Subject
Range
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...
2.0E-88 [6..258] [2..246]
TRNH5_ARATH - Tropinone reductase homolog At2g29260, chloroplastic OS=Arabidopsis thaliana GN=At2g29260 PE=2 SV=1
1.0E-84 [3..265] [64..321]
gi|25283158 - pir||C83961 3-oxoacyl-(acyl-carrier protein) reductase fabG [imported] - Bacillus halodurans (strain...
gi|10175111, gi|... - gi|15615054|ref|NP_243357.1| 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus halodurans C-125],...
3.0E-84 [7..258] [2..246]
gi|18310052, gi|... - gi|18310052|ref|NP_561986.1| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...
6.0E-83 [7..258] [2..246]
gi|1502421 - gi|1502421|gb|AAC44307.1| 3-ketoacyl-acyl carrier protein reductase
gi|1502421|gb|AA... - 3-ketoacyl-acyl carrier protein reductase
1.0E-82 [7..258] [2..246]
gi|221313791 - gi|221313791|ref|ZP_03595596.1| beta-ketoacyl-acyl carrier protein reductase [Bacillus subtilis subs...
gi|221318715 - gi|221318715|ref|ZP_03600009.1| beta-ketoacyl-acyl carrier protein reductase [Bacillus subtilis subs...
gi|221322986 - gi|221322986|ref|ZP_03604280.1| beta-ketoacyl-acyl carrier protein reductase [Bacillus subtilis subs...
FABG_BACSU - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Bacillus subtilis GN=fabG PE=3 SV=3
FABG_BACSU - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Bacillus subtilis (strain 168) GN=fabG PE=3 SV=3
3.0E-82 [7..258] [2..246]
gi|16800987 - gi|16800987|ref|NP_471255.1| hypothetical protein lin1921 [Listeria innocua Clip11262]
gi|25283285, gi|... - pir||AG1672 3-ketoacyl-acyl carrier protein reductase homolog fabG [imported] - Listeria innocua (st...
1.0E-80 [7..258] [3..247]
gi|227013918, gi... - gi|227118468|ref|YP_002820364.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio cholerae O395], ...
gi|227082148, gi... - gi|227082148|ref|YP_002810699.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio cholerae M66-2],...
gi|229507890, gi... - gi|229507890|ref|ZP_04397395.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae BX 33028...
gi|11354347 - gi|11354347|pir||F82128 3-oxoacyl-(acyl-carrier-protein) reductase VC2021 [imported] - Vibrio choler...
gi|229340858, gi... - gi|229521933|ref|ZP_04411350.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae TM 11079...
gi|229524031, gi... - gi|229524031|ref|ZP_04413436.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae bv. albe...
gi|229351840, gi... - gi|229511875|ref|ZP_04401354.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae B33], gi...
gi|229519011, gi... - gi|229519011|ref|ZP_04408454.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae RC9], gi...
gi|254849108, gi... - gi|254849108|ref|ZP_05238458.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio cholerae MO10], g...
gi|121730669, gi... - gi|121730669|ref|ZP_01682811.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio cholerae V52], gi...
gi|229528960, gi... - gi|229528960|ref|ZP_04418350.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae 12129(1)...
gi|9656565, gi|1... - gi|9656565|gb|AAF95169.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Vibrio cholerae O1 biovar El T...
gi|229370090, gi... - gi|229607435|ref|YP_002878083.1| 3-oxoacyl-[acyl-carrier protein] reductase [Vibrio cholerae MJ-1236...
2.0E-80 [1..258] [1..247]

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Predicted Domain #1
Region A:
Residues: [1-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELQSQPKK IAVVTGASGG IGYEVTKELA RNGYLVYACA RRLEPMAQLA IQFGNDSIKP  60
   61 YKLDISKPEE IVTFSGFLRA NLPDGKLDLL YNNAGQSCTF PALDATDAAV EQCFKVNVFG 120
  121 HINMCRELSE FLIKAKGTIV FTGSLAGVVS FPFGSIYSAS KAAIHQYARG LHLEMKPFNV 180
  181 RVINAITGGV ATDIADKRPL PETSIYNFPE GREAFNSRKT MAKDNKPMPA DAYAKQLVKD 240
  241 ILSTSDPVDV YRGTFANIMR FVMIFVPYWL LEKGLSKKFK LDKVNNALKS KQKNKDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 230.24799
Match: 1ae1A_
Description: Tropinone reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
structural molecule activity 2.31813292180084 bayes_pls_golite062009
acylglycerone-phosphate reductase activity 1.98546853223239 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
fatty acid synthase activity 0.714637370305282 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.62461633437589 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.233238483713519 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.192594057004213 bayes_pls_golite062009
nucleic acid binding 0.100470710829263 bayes_pls_golite062009
DNA binding 0.0870043837215047 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle