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View Structure Prediction Details

Protein: SIM1
Organism: Saccharomyces cerevisiae
Length: 475 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIM1.

Description E-value Query
Range
Subject
Range
gi|71064095 - gi|71064095|gb|AAZ22504.1| Sim1p [Saccharomyces cerevisiae]
385.0 [0..1] [475..1]
YBOH_SCHPO - Probable secreted beta-glucosidase C2G2.17c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
SPBC2G2.17c - beta-glucosidase Psu2
356.0 [0..206] [474..47]
gi|49527452, gi|... - gi|50291417|ref|XP_448141.1| unnamed protein product [Candida glabrata], gi|49527452|emb|CAG61092.1|...
gi|49527452 - gi|49527452|emb|CAG61092.1| unnamed protein product [Candida glabrata]
354.0 [0..202] [474..155]
gi|944922 - gi|944922|gb|AAC49038.1| beta-glucosidase
348.0 [0..3] [474..9]
gi|50310521, gi|... - gi|50310521|ref|XP_455280.1| unnamed protein product [Kluyveromyces lactis], gi|49644416|emb|CAG9798...
gi|49644416 - gi|49644416|emb|CAG97988.1| KLLA0F04433p [Kluyveromyces lactis]
333.0 [0..206] [475..145]

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Predicted Domain #1
Region A:
Residues: [1-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSTAVTTL ISSGAIVSAL PHVDVHQEDA HQHKRAVAYK YVYETVVVDS DGHTVTPAAS  60
   61 EVATAATSAI ITTSVLAPTS SAAAGIAASI AVSSAALAKN EKISDAAASA TASTSQGASS 120
  121 SSSSSSATST LESSSVSSSS EEAAPTSTVV STSSATQSSA SSATKSSTSS TSPSTSTSTS 180
  181 TSSTSSSSSS SSSSSSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 13.03
Match:
Description: No description for 1m2vB was found.

Predicted Domain #2
Region A:
Residues: [200-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGSIYGDLA DFSGPSEKFQ DGTIPCDKFP SGQGVISIDW IGEGGWSGVE NTDTSTGGSC  60
   61 KEGSYCSYSC QPGMSKTQWP SDQPSDGRSV GGLLCKNGYL YRSNTDADYL CEWGVEAAYV 120
  121 VSKLSKGVAI CRTDYPGTEN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.09691
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [340-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIPTYVEGG SSLPLTVVDQ DTYFTWEGKK TSAQYYVNNA GVSVEDGCIW GTSGSGIGNW  60
   61 APLNFGAGST GGVTYLSLIP NPNNSDALNY NVKIVAADDS SNVIGECVYE NGEFSGGADG 120
  121 CTVSVTSGKA HFVLYN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 39.79588
Match: PF03856
Description: Beta-glucosidase (SUN family)

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.292 N/A N/A d.129.3 Bet v1-like
View Download 0.276 N/A N/A d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.261 N/A N/A c.55.1 Actin-like ATPase domain
View Download 0.253 N/A N/A b.60.1 Lipocalins
View Download 0.249 N/A N/A b.60.1 Lipocalins
View Download 0.248 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.234 N/A N/A b.1.1 Immunoglobulin
View Download 0.210 N/A N/A b.60.1 Lipocalins
View Download 0.208 N/A N/A b.61.1 Avidin/streptavidin
View Download 0.203 N/A N/A b.18.1 Galactose-binding domain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle