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View Structure Prediction Details

Protein: MET30
Organism: Saccharomyces cerevisiae
Length: 640 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MET30.

Description E-value Query
Range
Subject
Range
MET30 - F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabol...
MET30_YEAST - F-box protein MET30 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET30 PE=1 SV=1
0.0 [1..640] [1..640]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [109..640] [901..1443]
HETE1_PODAS - Vegetative incompatibility protein HET-E-1 OS=Podospora anserina GN=HET-E1 PE=3 SV=1
0.0 [213..639] [833..1251]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRERQRMMS FEDKDKDDLD NSNSNNSSEM TDTAMMPPLK RLLITGSSDD LAQGSSGKKK  60
   61 MTMATRSPSS SPDLATNDSG TRVQPLPEYN FTKFCYRHNP DIQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.324 d.15.1 Ubiquitin-like
View Download 0.337 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.370 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.337 d.233.1 Inhibitor of vertebrate lysozyme, Ivy
View Download 0.477 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.477 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.370 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.337 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.337 d.233.1 Inhibitor of vertebrate lysozyme, Ivy
View Download 0.324 d.15.1 Ubiquitin-like
View Download 0.304 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.293 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.259 b.60.1 Lipocalins
View Download 0.239 a.150.1 Anti-sigma factor AsiA
View Download 0.239 d.228.1 Replication modulator SeqA, C-terminal DNA-binding domain
View Download 0.219 d.58.49 YajQ-like
View Download 0.209 b.60.1 Lipocalins

Predicted Domain #2
Region A:
Residues: [104-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSPTHTACYK QDLKRTQEIN ANIAKLPLQE QSDIHHIISK YSNSNDKIRK LILDGILSTS  60
   61 CFPQLSYISS LVTHMIKIDF ISILPQELSL KILSYLDCQS LCNATRVCRK WQKLADDDRV 120
  121 WYHMCEQHID RKCPNCGWGL PLLHMKRARI QQNSTGSSSN ADIQTQTTRP WKVIYRERFK 180
  181 VESNWRKGHC RIQEFKGHMD GVLTLQFNYR LLFTGSYDST IGIWDLFTGK LIRRLSGHSD 240
  241 GVKTLYFDDR KLITGSLDKT IRVWNYITGE CISTYRGHSD SVLSVDSYQK VIVSGSADKT 300
  301 VKVWHVESRT CYTLRGHTEW VNCVKLHPKS FSCFSCSDDT TIRMWDIRTN SCLKVFRGHV 360
  361 GQVQKIIPLT IKDVENLATD NTSDGSSPQD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 189.66807
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [494-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPTMTDGADE SDTPSNEQET VLDENIPYPT HLLSCGLDNT IKLWDVKTGK CIRTQFGHVE  60
   61 GVWDIAADNF RIISGSHDGS IKVWDLQSGK CMHTFNGRRL QRETQHTQTQ SLGDKVAPIA 120
  121 CVCIGDSECF SGDEFGCVKM YKFDLND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.9897
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle