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View Structure Prediction Details

Protein: BCY1
Organism: Saccharomyces cerevisiae
Length: 416 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BCY1.

Description E-value Query
Range
Subject
Range
KAPR_YEAST - cAMP-dependent protein kinase regulatory subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
gi|190406253 - gi|190406253|gb|EDV09520.1| cAMP-dependent protein kinase regulatory subunit [Saccharomyces cerevisi...
BCY1 - Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling path...
gi|151943126 - gi|151943126|gb|EDN61461.1| cAMP-dependent protein kinase regulatory subunit [Saccharomyces cerevisi...
0.0 [1..416] [1..416]
KAPR_BLAEM - cAMP-dependent protein kinase regulatory subunit OS=Blastocladiella emersonii GN=PKAR PE=2 SV=1
8.0E-86 [4..413] [5..394]
KAPR_EMENI - cAMP-dependent protein kinase regulatory subunit OS=Emericella nidulans GN=pkaR PE=3 SV=1
KAPR_EMENI - cAMP-dependent protein kinase regulatory subunit OS=Emericella nidulans (strain FGSC A4 / ATCC 38163...
5.0E-85 [43..410] [17..401]
KAP2_BOVIN - cAMP-dependent protein kinase type II-alpha regulatory subunit - Bos taurus (Bovine)
6.0E-84 [3..412] [3..378]
PRKAR2A - protein kinase, cAMP-dependent, regulatory, type II, alpha
gi|208967188 - gi|208967188|dbj|BAG73608.1| protein kinase, cAMP-dependent, regulatory, type II alpha [synthetic co...
9.0E-84 [3..412] [4..382]
gi|31543509, gi|... - gi|31543509|ref|NP_032949.2| protein kinase, cAMP dependent regulatory, type I beta [Mus musculus], ...
2.0E-83 [93..413] [42..371]
CNAG_00570.1, CN... - | Cryptococcus neoformans hypothetical protein similar to cAMP dependent protein kinase regulatory s...
gi|11096028 - gi|11096028|gb|AAG30146.1|AF288614_1 cAMP dependent protein kinase regulatory subunit [Cryptococcus ...
2.0E-83 [7..416] [2..473]

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Predicted Domain #1
Region A:
Residues: [1-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSSLPKESQ AELQLFQNEI NAANPSDFLQ FSANYFNKRL EQQRAFLKAR EPEFKAKNIV  60
   61 LFPEPEESFS RPQSAQSQSR SRSSVMFKSP FVNEDPHSNV FKSGFNLDPH EQDTHQQAQE 120
  121 EQQHTREKTS TPPLPMHFNA QRRTSVSGET LQPNNFDDWT PDHYKEKSEQ QLQRLEKSIR 180
  181 NNFLFNKLDS DSKRLVINCL EEKSVPKGAT IIKQGDQGDY FYVVEKGTVD FYVNDNKVNS 240
  241 SGPGSSFGEL ALMYNSPRAA TVVATSDCLL WALDRLTFRK ILLGSSFKKR LMYDDLLKSM 300
  301 PVLKSLTTYD RAKLADALDT KIYQPGETII REGDQGENFY LIEYGAVDVS KKGQGVINKL 360
  361 KDHDYFGEVA LLNDLPRQAT VTATKRTKVA TLGKSGFQRL LGPAVDVLKL NDPTRH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 629.927757
Match: 2apk__
Description: No description for 2apk__ was found.

Predicted Domain #2
Region A:
Residues: [152-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPNNFDDWTP DHYKEKSEQQ LQRLEKSIRN NFLFNKLDSD SKRLVINCLE EKSVPKGATI  60
   61 IKQGDQGDYF YVVEKGTVDF YVNDNKVNSS GPGSSFGELA LMYNSPRAAT VVATSDCLLW 120
  121 ALDRLTFRKI LLGSSFKKRL MYDDLLKSMP VLKSLTTYDR AKLADALDTK IYQPGETIIR 180
  181 EGDQGENFYL IEYGAVDVSK KGQGVINKLK DHDYFGEVAL LNDLPRQATV TATKRTKVAT 240
  241 LGKSGFQRLL GPAVDVLKLN DPTRH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 1rgsA
Description: REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle