YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM44
Organism:	Saccharomyces cerevisiae
Length:	431 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM44.

Description	E-value	Query Range	Subject Range
gi\|151943135 - gi\|151943135\|gb\|EDN61470.1\| translocase of the inner membrane [Saccharomyces cerevisiae YJM789] TIM44_YEAST - Mitochondrial import inner membrane translocase subunit TIM44 OS=Saccharomyces cerevisiae (strain AT... TIM44 - Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); tethers ... gi\|207344275 - gi\|207344275\|gb\|EDZ71473.1\| YIL022Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190406244 - gi\|190406244\|gb\|EDV09511.1\| hypothetical protein SCRG_05201 [Saccharomyces cerevisiae RM11-1a]	0.0	[1..431]	[1..431]
CG11779-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11779 (CG11779, FBgn0038683). It is a prote...	0.0	[41..430]	[63..458]
TIM44_RAT - Mitochondrial import inner membrane translocase subunit TIM44 OS=Rattus norvegicus GN=Timm44 PE=1 SV...	0.0	[37..429]	[47..451]
gi\|19483882 - gi\|19483882\|gb\|AAH23454.1\| Timm44 protein [Mus musculus]	0.0	[29..429]	[36..448]
gi\|4103602 - gi\|4103602\|gb\|AAD01797.1\| putative mitochondrial inner membrane protein import receptor [Homo sapien...	0.0	[38..429]	[10..413]
CE13473 - status:Confirmed UniProt:O02161 protein_id:AAB53011.1	0.0	[20..427]	[14..421]
TIM44_SCHPO - Mitochondrial import inner membrane translocase subunit tim44 OS=Schizosaccharomyces pombe (strain 9... tim44 - TIM23 translocase complex subunit Tim44	0.0	[14..425]	[4..421]
gi\|18399377, gi\|... - gi\|20198086\|gb\|AAD25651.2\| putative mitochondrial inner membrane translocating protein [Arabidopsis ...	0.0	[19..426]	[27..467]

Back

Predicted Domain #1

Region A:
Residues: [1-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRSTFIRTS GTSSRTLTAR YRSQYTGLLV ARVLFSTSTT RAQGGNPRSP LQIFRDTFKK  60
   61 EWEKSQELQE NIKTLQDASG KLGESEAYKK AREAYLKAQR GSTIVGKTLK KTGETMEHIA 120
  121 TKAWESELGK NTRKAAAATA KKLDESFEPV RQTKIYKEVS EVIDDGESSR YGGFITKEQR 180
  181 RLKRERDLAS GKRHRAVKSN EDAGTAVVAT NIESKESFGK KVEDFKEKTV VGRSIQSLKN 240
  241 KLWDES

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [247-431]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPLIVVMRK ITNKVGGFFA ETESSRVYSQ FKLMDPTFSN ESFTRHLREY IVPEILEAYV  60
   61 KGDVKVLKKW FSEAPFNVYA AQQKIFKEQD VYADGRILDI RGVEIVSAKL LAPQDIPVLV 120
  121 VGCRAQEINL YRKKKTGEIA AGDEANILMS SYAMVFTRDP EQIDDDETEG WKILEFVRGG 180
  181 SRQFT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits