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View Structure Prediction Details

Protein: MNT3
Organism: Saccharomyces cerevisiae
Length: 630 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNT3.

Description E-value Query
Range
Subject
Range
MNT3 - Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-link...
MNT3_YEAST - Alpha-1,3-mannosyltransferase MNT3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNT3 ...
0.0 [1..630] [1..630]
gi|1658377 - gi|1658377|gb|AAB18320.1| unknown [Pichia pastoris]
2.0E-45 [230..372] [140..279]

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Predicted Domain #1
Region A:
Residues: [1-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKSLKSRRL ILKRLVTLLL SLFFSYLIFS ASRNVTSSNK LNNHASERTA VESSAFNWIE  60
   61 KRQHQVRSEN LMNRLSAYFL PFLSRSSHKE RVLLRQLGNN EIAKSDKCRY IFEVLYKIDP 120
  121 DWDNAQTAKF YNVDGVDNTL ASLLGERLRS YDYCFLSGQL DPTAIFANST VNPHDLQNRM 180
  181 FPFLKKINEE SKTVMWPIIT DMTTGEAVPA PEVDMESSNF 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [221-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGNFWSNWNR LSKGRGFVLT IAEKDVPLFL KQLKVMEFSK NELPFQIVST GNELSAESIA  60
   61 KISETAKETE QRVYLVDCST VLDTNFANTY ISFFQNKWVA TLFNTFEEYI LLDADVVPFV 120
  121 GSDYFFDSPS YRESGILLFK DRVMENEQTF QYCIEMLNEV EPSA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.92
Match: 1ga8A
Description: Galactosyltransferase LgtC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyltransferase activity 2.72970569728159 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 1.64579615957842 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.58983046450767 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.18238034321908 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.539883035270389 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 0.373609073759347 bayes_pls_golite062009
nucleotidyltransferase activity 0.218795796569067 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 0.130891646999536 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [385-630]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QERRFIGSRL VFDSSLPFSS ETSEEASVYY NFFKKLRLHH VDSGLVVVNK LEKLNGLLMS  60
   61 FMLNLDGKLQ RCVYGDKEIF WLGQLYAGQD YSINPVDGSI IGPVNEEPEN DDGHKSGMYY 120
  121 ICSTQIAHSD SKNRLLWVNG GLKTCKISNS AEDDFGREPE YFKSRYGDIS KLKRIYDASL 180
  181 NVEGLIVPDV SVHPWMQIKE CSNYMYCAYA TGDGHTNSEL DEGRLITFTE KELRYINDIS 240
  241 RTWNAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle