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View Structure Prediction Details

Protein: YIA6
Organism: Saccharomyces cerevisiae
Length: 373 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIA6.

Description E-value Query
Range		 Subject
Range
gi|151943152 - gi|151943152|gb|EDN61487.1| NAD+ transporter [Saccharomyces cerevisiae YJM789]
gi|190406229 - gi|190406229|gb|EDV09496.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YIA6 - Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YE...
YIA6_YEAST - Mitochondrial nicotinamide adenine dinucleotide transporter 1 OS=Saccharomyces cerevisiae (strain AT...
 6.0E-83 [1..373] [1..373]
UCP3_PIG - Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3 PE=2 SV=1
 1.0E-81 [69..371] [5..303]
ADT3_BOVIN - ADP/ATP translocase 3 OS=Bos taurus GN=SLC25A6 PE=1 SV=3
 2.0E-81 [72..365] [3..298]
SLC25A31 - solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
gi|117645348 - gi|117645348|emb|CAL38140.1| hypothetical protein [synthetic construct]
HGNC:25319|MIM:6... - carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
 3.0E-81 [64..366] [7..309]
UCP3_MOUSE - Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3 PE=1 SV=1
 4.0E-81 [69..371] [5..303]
UCP3_RAT - Mitochondrial uncoupling protein 3 OS=Rattus norvegicus GN=Ucp3 PE=2 SV=1
 7.0E-81 [69..371] [5..303]

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Predicted Domain #1
Region A:
Residues: [1-72] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQTDNPVPN CGLLPEQQYC SADHEEPLLL HEEQLIFPDH SSQLSSADII EPIKMNSSTE  60
   61 SIIGTTLRKK WV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.271 b.36.1 PDZ domain-like
View Download 0.314 a.60.1 SAM/Pointed domain
View Download 0.257 a.61.1 Retroviral matrix proteins
View Download 0.384 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.588 a.112.1 Description not found.
View Download 0.234 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.205 a.150.1 Anti-sigma factor AsiA

Predicted Domain #2
Region A:
Residues: [73-373] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSSTQITAL SGAFAGFLSG VAVCPLDVAK TRLQAQGLQT RFENPYYRGI MGTLSTIVRD  60
   61 EGPRGLYKGL VPIVLGYFPT WMIYFSVYEF SKKFFHGIFP QFDFVAQSCA AITAGAASTT 120
  121 LTNPIWVVKT RLMLQSNLGE HPTHYKGTFD AFRKLFYQEG FKALYAGLVP SLLGLFHVAI 180
  181 HFPIYEDLKV RFHCYSRENN TNSINLQRLI MASSVSKMIA SAVTYPHEIL RTRMQLKSDI 240
  241 PDSIQRRLFP LIKATYAQEG LKGFYSGFTT NLVRTIPASA ITLVSFEYFR NRLENISTMV 300
  301 I

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.55
Match: 1is2A
Description: Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle