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View Structure Prediction Details

Protein: SPC97
Organism: Saccharomyces cerevisiae
Length: 823 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPC97.

Description E-value Query
Range
Subject
Range
SPC97 - Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the...
Spc97, YHR172W_W303 - SPC97 ORF Verified Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts ...
SPC97_YEAST - Spindle pole body component SPC97 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPC97 ...
0.0 [1..823] [1..823]
TUBGCP2 - tubulin, gamma complex associated protein 2
0.0 [4..823] [159..896]
GCP2_MOUSE - Gamma-tubulin complex component 2 OS=Mus musculus GN=Tubgcp2 PE=2 SV=1
0.0 [4..823] [159..899]
ALP4_SCHPO - Spindle pole body component alp4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alp4 PE=1...
alp4 - gamma tubulin complex Spc97 /GCP2 subunit Alp4
0.0 [55..771] [67..782]
Grip84-PC, FBpp0... - The gene gamma-tubulin ring protein 84 is referred to in FlyBase by the symbol Dmel\Grip84 (CG3917, ...
0.0 [51..793] [193..806]
SPC97_DICDI, SP9... - Spindle pole body component 97 - Dictyostelium discoideum (Slime mold), (Q95ZG3) Spindle pole body c...
0.0 [19..792] [216..972]
GACP3_ARATH - Gamma-tubulin complex component 3 OS=Arabidopsis thaliana GN=GCP3 PE=1 SV=1
0.0 [46..787] [176..804]
GCP3_XENLA - Gamma-tubulin complex component 3 homolog OS=Xenopus laevis GN=tubgcp3 PE=1 SV=1
0.0 [51..799] [241..892]

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Predicted Domain #1
Region A:
Residues: [1-53]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIKEVDDRA ELLRYTNNIP LLGKLVNHQP LWSTNPKLKS FSLEKISAPD QRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.347 a.4.1 Homeodomain-like
View Download 0.360 a.60.1 SAM/Pointed domain
View Download 0.348 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.414 g.58.1 Pheromone ER-23
View Download 0.354 a.60.1 SAM/Pointed domain
View Download 0.249 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.247 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.236 a.65.1 Annexin
View Download 0.221 a.5.1 DNA helicase RuvA subunit, C-terminal domain

Predicted Domain #2
Region A:
Residues: [54-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQEALVVKDL LNVLIGLEGT YIRYFNDYEP SDPETPIEFK IAKKMDPSFK TFSRRIVRYG  60
   61 KQYMILTRAY EKWSDTSFGM VLQRFAYEIR RFLEDVYLKT LVERLERDFN KVPNFSIREL 120
  121 EQIINETEVN KQMELLYNIY EEIFREIEER RTNQSSQEDF NNFMDSMKNE SSLHLRLMVA 180
  181 FDTTVYPVPK GGAILKIFQQ KILENLGDRS SVMFLKKLLN NISQDYCTML YEWLTQGILN 240
  241 DPYQEFMTYD DLEGKTDNIF DTRDRAWDTQ YFIRKDVLLR DCDSEEDKNL LFKMLRTGIL 300
  301 LKVVRASLQI PTIPSNSSDI TIQEINDFAD LMEGSNLELY VDKCYSRANE IFLKLFFQGY 360
  361 DLINVLKHLQ QIFLGYQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [431-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGHNVLKFLT KNMGELTKHY RNDNNANYDK LLQNFELERQ SENPNNLMRQ LLMIQFDTET  60
   61 LPQVLSHYLQ IYPEVPENNS ANDDSDPLMH ANNFKNMNAI LFDELSKERT GAYH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.638 a.1.1 Globin-like
View Download 0.423 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.517 a.64.1 Saposin
View Download 0.638 a.1.1 Globin-like
View Download 0.517 a.64.1 Saposin
View Download 0.460 a.1.1 Globin-like
View Download 0.460 a.1.1 Globin-like
View Download 0.423 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.410 i.11.1 Computational models partly based on NMR data
View Download 0.410 i.11.1 Computational models partly based on NMR data
View Download 0.390 a.77.1 DEATH domain
View Download 0.379 a.24.11 Bacterial GAP domain
View Download 0.338 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.334 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.315 a.29.2 Bromodomain
View Download 0.306 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.299 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.293 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.286 d.110.4 SNARE-like
View Download 0.277 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.257 d.134.1 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
View Download 0.254 a.24.11 Bacterial GAP domain
View Download 0.251 a.116.1 GTPase activation domain, GAP
View Download 0.243 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.242 a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.230 d.92.1 Metalloproteases ("zincins"), catalytic domain
View Download 0.223 a.1.1 Globin-like
View Download 0.220 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.220 d.79.1 YjgF-like
View Download 0.215 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.212 d.211.1 Ankyrin repeat
View Download 0.209 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.206 c.55.1 Actin-like ATPase domain

Predicted Domain #4
Region A:
Residues: [545-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNLELYTPK SAIYHLKFDI NIPYPLNIII SRTCMIKYQI ILRYQLVLQY HSRLLDETWM  60
   61 DLNKTPSWKY RGYSHTVKRR IVRATRVLHA KMNHFIKTIM EYFNQNVIDK EVYSLEKCYR 120
  121 NPTLAVAIQN ELEGGLTNIM TNRCLSDLIP LQLQIFDIVY KFCKFIKSMR AKLCQLDPVL 180
  181 YEKHKSGMMK TLNEGYRTNN GGQEDVGYQE DAALELIQKL IEYISNASSI FRKCLINFTQ 240
  241 ELSTEKFDFY DSSSVDAAGI ERVLYSIVPP RSASASSQR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.03
Match: 1ldjA
Description: Anaphase promoting complex (APC); Cullin homolog 1, Cul-1; Cullin homolog 1, cul-1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [720-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDPVLYEKHK SGMMKTLNEG YRTNNGGQED VGYQEDAALE LIQKLIEYIS NASSIFRKCL  60
   61 INFTQELSTE KFDFYDSSSV DAAGIERVLY SIVPPRSASA SSQR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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