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View Structure Prediction Details

Protein: CDC12
Organism: Saccharomyces cerevisiae
Length: 407 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC12.

Description E-value Query
Range
Subject
Range
gi|220955920, gi... - gi|220955920|gb|ACL90503.1| pnut-PA [synthetic construct], gi|220946224|gb|ACL85655.1| pnut-PA [synt...
pnut-PA, pnut-PB - The gene peanut is referred to in FlyBase by the symbol Dmel\pnut (CG8705, FBgn0013726). It is a pro...
0.0 [3..383] [111..482]
SEPT7_RAT - Septin-7 OS=Rattus norvegicus GN=Sept7 PE=1 SV=1
0.0 [3..407] [18..411]
SEPT7_MOUSE - Septin-7 OS=Mus musculus GN=Sept7 PE=1 SV=1
0.0 [4..407] [19..411]
SEPT4 - septin 4
3.0E-98 [14..363] [124..474]
gi|1791305 - gi|1791305|gb|AAB41233.1| septin B [Emericella nidulans]
1.0E-96 [9..398] [7..389]

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Predicted Domain #1
Region A:
Residues: [1-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAATATAAP VPPPVGISNL PNQRYKIVNE EGGTFTVMLC GESGLGKTTF INTLFQTVLK  60
   61 RADGQQHRQE PIRKTVEIDI TRALLEEKHF ELRVNVIDTP GFGDNVNNNK AWQPLVDFID 120
  121 DQHDSYMRQE QQPYRTKKFD LRVHAVLYFI RPTGHGLKPI DIETMKRLST RANLIPVIAK 180
  181 ADTLTAQELQ QFKSRIRQVI EAQEIRIFTP PLDADSKEDA KSGSNPDSAA VEHARQLIEA 240
  241 MPFAIVGSEK KFDNGQGTQV VARKYPWGLV EIEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1egaA_
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [275-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSHCDFRKLR ALLLRTYLLD LISTTQEMHY ETYRRLRLEG HENTGEGNED FTLPAIAPAR  60
   61 KLSHNPRYKE EENALKKYFT DQVKAEEQRF RQWEQNIVNE RIRLNGDLEE IQGKVKKLEE 120
  121 QVKSLQVKKS HLK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.927 0.025 axial cellular bud site selection a.7.4 Smac/diablo


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle