YRC Public Data Repository - Protein Structure Prediction

Protein:	PTC7
Organism:	Saccharomyces cerevisiae
Length:	374 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTC7.

Description	E-value	Query Range	Subject Range
gi\|190405858 - gi\|190405858\|gb\|EDV09125.1\| type 2C protein Phosphatase [Saccharomyces cerevisiae RM11-1a] gi\|207344675 - gi\|207344675\|gb\|EDZ71739.1\| YHR076Wp-like protein [Saccharomyces cerevisiae AWRI1631] PTC7 - Type 2C protein phosphatase; YHR076W is alternatively spliced to create two mRNA isoforms; protein f...	3.0E-87	[1..374]	[1..374]
P2C77_ARATH - Protein phosphatase 2C 77 OS=Arabidopsis thaliana GN=ABI2 PE=1 SV=1	7.0E-64	[36..373]	[58..411]
gi\|7768151 - gi\|7768151\|emb\|CAB90633.1\| protein phpsphatase 2C (PP2C) [Fagus sylvatica]	7.0E-59	[66..373]	[96..407]
PPM1A_RABIT - Protein phosphatase 1A OS=Oryctolagus cuniculus GN=PPM1A PE=2 SV=1	1.0E-55	[106..371]	[22..289]
CCDS9744.1_1 - null PPM1A - protein phosphatase, Mg2+/Mn2+ dependent, 1A gi\|114653343, gi... - gi\|114653347\|ref\|XP_509986.2\| PREDICTED: hypothetical protein LOC452950 isoform 9 [Pan troglodytes],... gi\|109083826, gi... - gi\|109083828\|ref\|XP_001096358.1\| PREDICTED: similar to protein phosphatase 1A isoform 1 isoform 5 [M... gi\|123996549, gi... - gi\|168279063\|dbj\|BAG11411.1\| protein phosphatase 1A [synthetic construct], gi\|123996549\|gb\|ABM85876....	2.0E-55	[106..371]	[22..289]
PPM1A_RAT - Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a PE=1 SV=1	2.0E-55	[106..371]	[22..289]

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Predicted Domain #1

Region A:
Residues: [1-82]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFANVGFRTL RVSRGPLYGM FIVLFIGVLI AKFAGQMLID SETNFSHIIG SCSQIISFSK  60
   61 RTFYSSAKSG YQSNNSHGDA YS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [83-374]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSQSGPFTY KTAVAFQPKD RDDLIYQKLK DSIRSPTGED NYFVTSNNVH DIFAGVADGV  60
   61 GGWAEHGYDS SAISRELCKK MDEISTALAE NSSKETLLTP KKIIGAAYAK IRDEKVVKVG 120
  121 GTTAIVAHFP SNGKLEVANL GDSWCGVFRD SKLVFQTKFQ TVGFNAPYQL SIIPEEMLKE 180
  181 AERRGSKYIL NTPRDADEYS FQLKKKDIII LATDGVTDNI ATDDIELFLK DNAARTNDEL 240
  241 QLLSQKFVDN VVSLSKDPNY PSVFAQEISK LTGKNYSGGK EDDITVVVVR VD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.30103
Match:	1a6q__
Description:	Protein serine/threonine phosphatase 2C, C-terminal domain; Protein serine/threonine phosphatase 2C, catalytic domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits