YRC Public Data Repository - Protein Structure Prediction

Protein:	HTD2
Organism:	Saccharomyces cerevisiae
Length:	280 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HTD2.

Description	E-value	Query Range	Subject Range
gi\|151944011 - gi\|151944011\|gb\|EDN62304.1\| hydroxyacyl-thioester dehydratase [Saccharomyces cerevisiae YJM789] HTD2_YEAST - Hydroxyacyl-thioester dehydratase type 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204... HTD2 - Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for ... gi\|207344687 - gi\|207344687\|gb\|EDZ71747.1\| YHR067Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405849 - gi\|190405849\|gb\|EDV09116.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]	0.0	[1..280]	[1..280]
gi\|11349021 - pir\|\|D83536 hypothetical protein PA0878 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|15596075, gi\|... - gi\|9946777\|gb\|AAG04267.1\|AE004522_9 hypothetical protein PA0878 [Pseudomonas aeruginosa PAO1], gi\|15... gi\|107100336 - gi\|107100336\|ref\|ZP_01364254.1\| hypothetical protein PaerPA_01001361 [Pseudomonas aeruginosa PACS2] gi\|126171162, gi... - gi\|84316648\|ref\|ZP_00965120.1\| COG3777: Uncharacterized conserved protein [Pseudomonas aeruginosa C3... gi\|254245165, gi... - gi\|84322687\|ref\|ZP_00970771.1\| COG3777: Uncharacterized conserved protein [Pseudomonas aeruginosa 21... gi\|218893153, gi... - gi\|218893153\|ref\|YP_002442022.1\| hypothetical protein PLES_44381 [Pseudomonas aeruginosa LESB58], gi...	2.0E-83	[10..248]	[18..246]
HTD2_SCHPO - Hydroxyacyl-thioester dehydratase type 2, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / A... htd2 - 3-hydroxyacyl-ACP dehydratase Htd2	3.0E-80	[7..251]	[6..273]
gi\|25397302 - pir\|\|A87387 hypothetical protein CC1109 [imported] - Caulobacter crescentus gi\|13422419, gi\|... - gi\|16125361\|ref\|NP_419925.1\| hypothetical protein CC_1109 [Caulobacter crescentus CB15], gi\|13422419... gi\|220963275, gi... - gi\|221234103\|ref\|YP_002516539.1\| conserved cytosolic protein [Caulobacter crescentus NA1000], gi\|220...	3.0E-70	[11..247]	[17..237]
gi\|17985296, gi\|... - gi\|17989420\|ref\|NP_542053.1\| putative cytoplasmic protein [Brucella melitensis 16M], gi\|17985296\|gb\|... gi\|25525276 - pir\|\|AB3644 hypothetical cytosolic protein BMEII1075 [imported] - Brucella melitensis (strain 16M)	1.0E-68	[4..248]	[7..248]

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Predicted Domain #1

Region A:
Residues: [1-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSKTWIFRD VLSSHRTKAF DSLLCRRLPV SKATKHLQLG EHFLFFPPSF EKLDRDGYFN  60
   61 YQNPASLLGN PDLRYRRRIW GQGELVQYLP VTLDQEYTCH ESIKYVKKIR DEHVVCIERT 120
  121 LLQERPENVS SPMDICLFER RVLMYTNSPA NKTAVKMPVG EENYKILKNF TVTDMDIVAY 180
  181 GQMSLNPHRI HWDKEYSRYV EGYDDIIMQG PFSVQLLQKC IQPFLEQPIR QLRYRNLNYI 240
  241 YPNTTLSICQ SLSSSSGMYT FQIRDLQKAN LVYMKADVFC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits