YRC Public Data Repository - Protein Structure Prediction

Protein:	DOG1
Organism:	Saccharomyces cerevisiae
Length:	246 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOG1.

Description	E-value	Query Range	Subject Range
DOG2_YEAST - 2-deoxyglucose-6-phosphate phosphatase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... DOG2 - 2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, sim...	3.0E-49	[1..245]	[1..245]
G3PP_PYRAB - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB05140 PE=3 ... YB10_PYRAB - Uncharacterized HAD-hydrolase PYRAB05140 OS=Pyrococcus abyssi GN=PYRAB05140 PE=3 SV=1	1.0E-37	[6..243]	[2..237]
GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae GN=gph PE=3 SV=1	3.0E-37	[1..229]	[1..224]
YG55_PYRHO, Y165... - (O59346) Putative HAD-hydrolase PH1655 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PH1655 OS=Pyrococ... G3PP_PYRHO - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JC...	3.0E-36	[6..242]	[2..237]
GPH_PASMU - Phosphoglycolate phosphatase OS=Pasteurella multocida (strain Pm70) GN=gph PE=3 SV=1 GPH_PASMU - Phosphoglycolate phosphatase OS=Pasteurella multocida GN=gph PE=3 SV=1	1.0E-35	[1..230]	[1..224]
Y1777_PYRFU, YH7... - (Q8U040) Putative HAD-hydrolase PF1777 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PF1777 OS=Pyrococ... G3PP_PYRFU - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 84...	2.0E-35	[5..241]	[3..238]
gi\|15832431, gi\|... - gi\|15832431\|ref\|NP_311204.1\| putative phosphatase [Escherichia coli O157:H7 str. Sakai], gi\|13362647... gi\|189362785, gi... - gi\|189362785\|gb\|EDU81204.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4486], gi\|16876... gi\|110615804, gi... - gi\|110806256\|ref\|YP_689776.1\| putative phosphatase [Shigella flexneri 5 str. 8401], gi\|110615804\|gb\|... gi\|187771241, gi... - gi\|187771241\|gb\|EDU35085.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|168780150, gi... - gi\|189002163\|gb\|EDU71149.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4076], gi\|16878... gi\|189372899, gi... - gi\|189372899\|gb\|EDU91315.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC869], gi\|168787... gi\|188017347, gi... - gi\|188017347\|gb\|EDU55469.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4113], gi\|16874... gi\|168755047, gi... - gi\|189357610\|gb\|EDU76029.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4401], gi\|16875... gi\|168761266, gi... - gi\|189368321\|gb\|EDU86737.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4501], gi\|16876... gi\|24113665, gi\|... - gi\|24113665\|ref\|NP_708175.1\| putative phosphatase [Shigella flexneri 2a str. 301], gi\|24052730\|gb\|AA... gi\|254794185, gi... - gi\|254794185\|ref\|YP_003079022.1\| sugar phosphatase [Escherichia coli O157:H7 str. TW14359], gi\|25459... gi\|209765036, gi... - pir\|\|B85870 probable phosphatase yfbT [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15832431, gi\|... - gi\|15832431\|ref\|NP_311204.1\| putative phosphatase [Escherichia coli O157:H7], gi\|13362647\|dbj\|BAB366... gi\|30063719, gi\|... - gi\|30063719\|ref\|NP_837890.1\| putative phosphatase [Shigella flexneri 2a str. 2457T], gi\|30041974\|gb\|... gi\|15802840, gi\|... - gi\|15802840\|ref\|NP_288867.1\| putative phosphatase [Escherichia coli O157:H7 EDL933], gi\|12516646\|gb\|... gi\|208740594, gi... - gi\|208820471\|ref\|ZP_03260791.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|209400370, gi... - gi\|209400370\|ref\|YP_002271702.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4115], gi\|... gi\|217326756, gi... - gi\|217326756\|ref\|ZP_03442839.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. TW14588], gi\|... gi\|218700767, gi... - gi\|218700767\|ref\|YP_002408396.1\| putative phosphatase [Escherichia coli IAI39], gi\|218370753\|emb\|CAR... gi\|168798465, gi... - gi\|189378878\|gb\|EDU97294.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC508], gi\|168798... gi\|195935671 - gi\|195935671\|ref\|ZP_03081053.1\| putative phosphatase [Escherichia coli O157:H7 str. EC4024] gi\|208806086, gi... - gi\|208806086\|ref\|ZP_03248423.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4206], gi\|2... gi\|208814427, gi... - gi\|208814427\|ref\|ZP_03255756.1\| sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4045], gi\|2...	4.0E-35	[4..238]	[1..216]
gi\|115345978, gi... - gi\|218927367\|ref\|YP_002345242.1\| phosphoglycolate phosphatase [Yersinia pestis CO92], gi\|16120499\|re... gi\|167051130, gi... - gi\|167398626\|ref\|ZP_02304150.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Anti... gi\|167419309, gi... - gi\|167419309\|ref\|ZP_02311062.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Orie... gi\|167425714, gi... - gi\|167425714\|ref\|ZP_02317467.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Medi... gi\|167468238 - gi\|167468238\|ref\|ZP_02332942.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis FV-1] gi\|149290246, gi... - gi\|150260838\|ref\|ZP_01917566.1\| phosphoglycolate phosphatase [Yersinia pestis CA88-4125], gi\|1492902... gi\|170022491, gi... - gi\|170022491\|ref\|YP_001718996.1\| phosphoglycolate phosphatase [Yersinia pseudotuberculosis YPIII], g... gi\|162418394, gi... - gi\|77634597\|ref\|ZP_00796694.1\| COG0546: Predicted phosphatases [Yersinia pestis Angola], gi\|16241839... gi\|161484727 - gi\|161484727\|ref\|NP_671232.2\| phosphoglycolate phosphatase [Yersinia pestis KIM] gi\|77631137, gi\|... - gi\|77631137\|ref\|ZP_00793723.1\| COG0546: Predicted phosphatases [Yersinia pseudotuberculosis IP 31758... gi\|161511472 - gi\|161511472\|ref\|NP_991559.2\| phosphoglycolate phosphatase [Yersinia pestis biovar Microtus str. 910... gi\|229842093, gi... - gi\|229842093\|ref\|ZP_04462248.1\| phosphoglycolate phosphatase [Yersinia pestis biovar Orientalis str.... gi\|162100162 - gi\|162100162\|ref\|YP_653220.2\| phosphoglycolate phosphatase [Yersinia pestis Antiqua] gi\|229696378, gi... - gi\|229840012\|ref\|ZP_04460171.1\| phosphoglycolate phosphatase [Yersinia pestis biovar Orientalis str.... gi\|229904606, gi... - gi\|229904606\|ref\|ZP_04519717.1\| phosphoglycolate phosphatase [Yersinia pestis Nepal516], gi\|22967872... gi\|229836363, gi... - gi\|229836363\|ref\|ZP_04456530.1\| phosphoglycolate phosphatase [Yersinia pestis Pestoides A], gi\|22970... gi\|162202303 - gi\|162202303\|ref\|YP_001161481.2\| phosphoglycolate phosphatase [Yersinia pestis Pestoides F] gi\|165928036, gi... - gi\|165928036\|ref\|ZP_02223868.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Orie... gi\|166010480, gi... - gi\|166010480\|ref\|ZP_02231378.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Anti... gi\|166205544, gi... - gi\|166213246\|ref\|ZP_02239281.1\| phosphoglycolate phosphatase, bacterial [Yersinia pestis biovar Anti... GPH_YERPE - Phosphoglycolate phosphatase OS=Yersinia pestis GN=gph PE=3 SV=1 gi\|89105795, gi\|... - gi\|89105795\|ref\|ZP_01178308.1\| COG0546: Predicted phosphatases [Yersinia pestis biovar Orientalis st...	4.0E-35	[6..229]	[7..222]
gi\|126520826, gi... - gi\|153821629\|ref\|ZP_01974296.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|153829003, gi... - gi\|153829003\|ref\|ZP_01981670.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|227811728, gi... - gi\|227811728\|ref\|YP_002811738.1\| CbbY family protein [Vibrio cholerae M66-2], gi\|227010870\|gb\|ACP070... gi\|227119283, gi... - gi\|227119283\|ref\|YP_002821178.1\| CbbY family protein [Vibrio cholerae O395], gi\|227014733\|gb\|ACP1094... gi\|121726959, gi... - gi\|121726959\|ref\|ZP_01680155.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|121586870, gi... - gi\|121586870\|ref\|ZP_01676651.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|153221840, gi... - gi\|153221840\|ref\|ZP_01952705.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|9657489, gi\|1... - gi\|9657489\|gb\|AAF96016.1\| CbbY family protein [Vibrio cholerae O1 biovar eltor str. N16961], gi\|1560... gi\|124116239, gi... - gi\|153212861\|ref\|ZP_01948478.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|11354451 - pir\|\|A82498 CbbY family protein VCA0102 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|126511761, gi... - gi\|153817719\|ref\|ZP_01970386.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole... gi\|254850367, gi... - gi\|254850367\|ref\|ZP_05239717.1\| haloacid dehalogenase/epoxide hydrolase family protein [Vibrio chole...	5.0E-35	[1..233]	[1..219]

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Predicted Domain #1

Region A:
Residues: [1-20]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEFSADLCL FDLDGTIVST

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [79-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSYLDTVSLI PGAENLLLSL DVDTETQKKL PERKWAIVTS GSPYLAFSWF ETILKNVGKP  60
   61 KVFITGFDVK NGKPDPEGYS RARDLLRQDL QLTGKQDLKY VVFEDAPVGI KAGKAMGAIT 120
  121 VGITSSYDKS VLFDAGADYV VCDLTQVSVV KNNENGIVIQ VNNPLTRA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [21-78]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVAAEKAWTK LCYEYGVDPS ELFKHSHGAR TQEVLRRFFP KLDDTDNKGV LALEKDIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1jud__
Description:	L-2-Haloacid dehalogenase, HAD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits