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View Structure Prediction Details

Protein: NCP1
Organism: Saccharomyces cerevisiae
Length: 691 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NCP1.

Description E-value Query
Range
Subject
Range
NCP1 - NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately reg...
NCPR_YEAST - NADPH--cytochrome P450 reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCP1 PE...
0.0 [1..691] [1..691]
NCPR_PIG - NADPH--cytochrome P450 reductase OS=Sus scrofa GN=POR PE=1 SV=2
0.0 [5..691] [22..677]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [5..691] [21..676]
POR - P450 (cytochrome) oxidoreductase
0.0 [5..691] [22..676]
gi|1101789 - gi|1101789|gb|AAA82951.1| NADPH-cytochrome P450 reductase
0.0 [5..691] [30..685]
NCPR_RAT - NADPH--cytochrome P450 reductase OS=Rattus norvegicus GN=Por PE=1 SV=3
0.0 [5..691] [22..677]

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Predicted Domain #1
Region A:
Residues: [1-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFGIDNTDF TVLAGLVLAV LLYVKRNSIK ELLMSDDGDI TAVSSGNRDI AQVVTENNKN  60
   61 YLVLYASQTG TAEDYAKKFS KELVAKFNLN VMCADVENYD FESLNDVPVI VSIFISTYGE 120
  121 GDFPDGAVNF EDFICNAEAG ALSNLRYNMF GLGNSTYEFF NGAAKKAEKH LSAAGAIRLG 180
  181 KLGEADDGAG TTDEDYMAWK DSILEVLKDE LHLDEQEAKF TSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1886.9897
Match: 1amoA_
Description: NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [224-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQYTVLNEIT DSMSLGEPSA HYLPS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [312-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNPLEKVEQF LSIFNLDPET IFDLKPLDPT VKVPFPTPTT IGAAIKHYLE ITGPVSRQLF  60
   61 SSLIQFAPNA DVKEKLTLLS KDKDQFAVEI TSKYFNIADA LKYLSDGAKW DTVPMQFLVE 120
  121 SVPQMT

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [462-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFPNPELPDA PPVVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1886.9897
Match: 1amoA_
Description: NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [249-311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQLNRNADGI QLGPFDLSQP YIAPIVKSRE LFSSNDRNCI HSEFDLSGSN IKYSTGDHLA  60
   61 VWP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [438-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRYYSISSSS LSEKQTVHVT SIVE

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [477-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTTNLLRNIQ LAQNNVNIAE TNLPVHYDLN GPRKLFANYK LPVHVRRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1886.9897
Match: 1amoA_
Description: NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [525-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFRLPSNPST PVIMIGPGTG VAPFRGFIRE RVAFLESQKK GGNNVSLGKH ILFYGSRNTD  60
   61 DFLYQDEWPE YAKKLDGSFE MVVAHSRLPN TKKVYVQDKL KDYEDQVFEM INNGAFIYVC 120
  121 GDAKGMAKGV STALVGILSR GKSITTDEAT ELIKMLKTSG RYQEDVW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1886.9897
Match: 1amoA_
Description: NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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