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View Structure Prediction Details

Protein: YSC84
Organism: Saccharomyces cerevisiae
Length: 468 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YSC84.

Description E-value Query
Range
Subject
Range
YSC84 - Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patc...
YSC84_YEAST - Protein YSC84 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YSC84 PE=1 SV=2
gi|190405801 - gi|190405801|gb|EDV09068.1| hypothetical protein SCRG_04722 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..468] [1..468]
YIE2_SCHPO - SH3 domain-containing protein PJ696.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPA...
SPAPJ696.02 - actin cortical patch component Lsb4
1.0E-95 [1..468] [1..430]
SH3YL1 - SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
gi|190689283, gi... - gi|190690635|gb|ACE87092.1| SH3 domain containing, Ysc84-like 1 (S. cerevisiae) protein [synthetic c...
4.0E-73 [3..284] [1..266]
gi|7649363, gi|2... - gi|7649363|emb|CAB89044.1| putative protein [Arabidopsis thaliana], gi|20465341|gb|AAM20074.1| unkno...
1.0E-72 [3..211] [268..476]
SH3Y1_MOUSE - SH3 domain-containing YSC84-like protein 1 OS=Mus musculus GN=Sh3yl1 PE=1 SV=1
2.0E-71 [3..273] [1..250]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGINNPIPRS LKSETKKAAK VLRSFVKPNQ VFGADQVIPP YVLKRAKGLA IITVLKAGFL  60
   61 FSGRAGSGVI VARLKDGTWS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.398 0.320 actin cortical patch a.4.5 "Winged helix" DNA-binding domain
View Download 0.437 0.042 actin cortical patch d.1.1 Microbial ribonucleases
View Download 0.384 0.031 actin cortical patch c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.507 0.020 actin cortical patch a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.396 0.010 actin cortical patch d.39.1 Dynein light chain 8 (DLC8)
View Download 0.507 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.437 N/A N/A d.1.1 Microbial ribonucleases
View Download 0.398 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.396 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.384 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.377 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.352 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.351 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.340 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.307 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.277 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.274 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.271 N/A N/A a.130.1 Chorismate mutase II
View Download 0.266 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.266 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.258 N/A N/A a.39.1 EF-hand
View Download 0.256 N/A N/A b.82.3 cAMP-binding domain-like
View Download 0.255 N/A N/A d.1.1 Microbial ribonucleases
View Download 0.252 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.240 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.230 N/A N/A d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.229 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.226 N/A N/A a.39.1 EF-hand
View Download 0.221 N/A N/A a.2.7 tRNA-binding arm
View Download 0.218 N/A N/A b.7.3 PHL pollen allergen
View Download 0.205 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.205 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.205 N/A N/A a.77.1 DEATH domain
View Download 0.203 N/A N/A c.47.1 Thioredoxin-like
View Download 0.202 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [81-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APSAIAMAGA GAGGMVGVEL TDFVFILNSE EAVRSFSEFG TITLGGNVSV SAGPLGRSAE  60
   61 AAASASTGGV SAVFAYSKSK GLFAGVSVEG SAILERREAN RKFYGDNCTS KMILSGRVKV 120
  121 PPAADPLLRI LESRAFNFTR HDHDDNASGD DFYDDGQYSD NTSHYYDDIP DSFDSTDESS 180
  181 TRPNTRSSRR RGMSLGSRSR YDDDYDDDGY GRGRGYGDFD SEDEDYDYGR SPNRNSSRNR 240
  241 GPQIDRGTKP RANTRWEDDL YDRDTEYSRP NHSGRDYDNT RGNRRGYGRE RGYSLGHGPT 300
  301 HPSNMSNVDD LSHKMSKTGL GNESTATNSA TPT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.31
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [414-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVALYNFAGE QPGDLAFKKG DVITILKKSD SQNDWWTGRT NGKEGIFPAN YVRVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.325697
Match: 1semA_
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [387-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVDDLSHKMS KTGLGNESTA TNSATPTAVA LYNFAGEQPG DLAFKKGDVI TILKKSDSQN  60
   61 DWWTGRTNGK EGIFPANYVR VS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2a08A
Description: No description for 2a08A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle