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View Structure Prediction Details

Protein: DIA4
Organism: Saccharomyces cerevisiae
Length: 446 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIA4.

Description E-value Query
Range
Subject
Range
SYS_PSEAE - Seryl-tRNA synthetase OS=Pseudomonas aeruginosa GN=serS PE=3 SV=1
SYS_PSEAE - Serine--tRNA ligase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) ...
gi|254235598, gi... - gi|84320581|ref|ZP_00968954.1| COG0172: Seryl-tRNA synthetase [Pseudomonas aeruginosa C3719], gi|254...
gi|194552030, gi... - gi|84326939|ref|ZP_00974963.1| COG0172: Seryl-tRNA synthetase [Pseudomonas aeruginosa 2192], gi|2542...
SYS_PSEA8 - Serine--tRNA ligase OS=Pseudomonas aeruginosa (strain LESB58) GN=serS PE=3 SV=1
SYS_PSEAB - Serine--tRNA ligase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=serS PE=3 SV=1
gi|107102134 - gi|107102134|ref|ZP_01366052.1| hypothetical protein PaerPA_01003183 [Pseudomonas aeruginosa PACS2]
0.0 [20..446] [1..425]
gi|25293165 - pir||D97918 serine-tRNA ligase (EC 6.1.1.11) [imported] - Streptococcus pneumoniae (strain R6)
gi|15902416, gi|... - gi|15902416|ref|NP_357966.1| seryl-tRNA synthetase [Streptococcus pneumoniae R6], gi|15457932|gb|AAK...
0.0 [14..446] [16..443]
SYS_LACLA - Seryl-tRNA synthetase OS=Lactococcus lactis subsp. lactis GN=serS PE=3 SV=1
SYS_LACLA - Serine--tRNA ligase OS=Lactococcus lactis subsp. lactis (strain IL1403) GN=serS PE=3 SV=1
0.0 [20..446] [1..422]
SYS_STRPY - (Q99YE2) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS)
gi|13622796, gi|... - gi|15675591|ref|NP_269765.1| seryl-tRNA synthetase [Streptococcus pyogenes M1 GAS], gi|13622796|gb|A...
SYS_STRP1 - Serine--tRNA ligase OS=Streptococcus pyogenes serotype M1 GN=serS PE=3 SV=1
gi|71911296, gi|... - gi|71911296|ref|YP_282846.1| seryl-tRNA synthetase [Streptococcus pyogenes MGAS5005], gi|71854078|gb...
0.0 [20..446] [1..422]
SYS_STRP8 - Serine--tRNA ligase OS=Streptococcus pyogenes serotype M18 (strain MGAS8232) GN=serS PE=3 SV=1
SYS_STRP6 - Serine--tRNA ligase OS=Streptococcus pyogenes serotype M6 GN=serS PE=3 SV=1
SYS_STRP8 - Serine--tRNA ligase OS=Streptococcus pyogenes serotype M18 GN=serS PE=3 SV=1
SYS_STRP6 - Serine--tRNA ligase OS=Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394) GN=serS ...
0.0 [20..446] [1..422]
gi|183577467, gi... - gi|183577467|gb|EDT97995.1| seryl-tRNA synthetase [Streptococcus pneumoniae MLV-016], gi|168576870|r...
gi|149023698, gi... - gi|149023698|ref|ZP_01836178.1| seryl-tRNA synthetase [Streptococcus pneumoniae SP23-BS72], gi|14792...
SYS_STRPN - Serine--tRNA ligase OS=Streptococcus pneumoniae GN=serS PE=3 SV=1
SYS_STRPN - Serine--tRNA ligase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=serS PE=...
gi|147757389, gi... - gi|148996814|ref|ZP_01824532.1| seryl-tRNA synthetase [Streptococcus pneumoniae SP11-BS70], gi|14775...
SYS_STRZT - Serine--tRNA ligase OS=Streptococcus pneumoniae (strain Taiwan19F-14) GN=serS PE=3 SV=1
gi|242246026, gi... - gi|242246026|ref|ZP_04800463.1| seryl-tRNA synthetase [Streptococcus pneumoniae TCH8431/19A], gi|242...
0.0 [20..446] [1..422]
SYS_PASMU - Seryl-tRNA synthetase OS=Pasteurella multocida GN=serS PE=3 SV=1
SYS_PASMU - Serine--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=serS PE=3 SV=1
0.0 [20..446] [1..427]
SYS_ECO7I - Serine--tRNA ligase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=serS PE=3 SV=1
SYS_ECOLU - Serine--tRNA ligase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=serS PE=3 SV=1
SYS_ECO5E - Serine--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=serS PE=3 SV=1
SYS_ECOSE - Serine--tRNA ligase OS=Escherichia coli (strain SE11) GN=serS PE=3 SV=1
SYS_ECO27 - Serine--tRNA ligase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=serS PE=3 SV=1
gi|217326397, gi... - gi|217326397|ref|ZP_03442481.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588], gi|21...
SYS_ECO8A - Serine--tRNA ligase OS=Escherichia coli O8 (strain IAI1) GN=serS PE=3 SV=1
SYS_ECO45 - Serine--tRNA ligase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=serS PE=3 SV=1
SYS_ECO81 - Serine--tRNA ligase OS=Escherichia coli O81 (strain ED1a) GN=serS PE=3 SV=1
SYS_ECO55 - Serine--tRNA ligase OS=Escherichia coli (strain 55989 / EAEC) GN=serS PE=3 SV=1
sp|B7UMY4|SYS_ECO27 - Seryl-tRNA synthetase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=serS PE=3 SV=1
SYS_SHISS - Serine--tRNA ligase OS=Shigella sonnei (strain Ss046) GN=serS PE=3 SV=1
SYS_SHIBS - Serine--tRNA ligase OS=Shigella boydii serotype 4 (strain Sb227) GN=serS PE=3 SV=1
gi|75257392, gi|... - gi|75257392|ref|ZP_00728908.1| COG0172: Seryl-tRNA synthetase [Escherichia coli E22], gi|193064674|r...
gi|188492608, gi... - gi|75512046|ref|ZP_00734631.1| COG0172: Seryl-tRNA synthetase [Escherichia coli 53638], gi|188492608...
gi|194438706, gi... - gi|83585836|ref|ZP_00924476.1| COG0172: Seryl-tRNA synthetase [Escherichia coli 101-1], gi|194438706...
gi|13360437, gi|... - gi|15830232|ref|NP_309005.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi|1336043...
gi|189372720, gi... - gi|189372720|gb|EDU91136.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi|16878732...
SYS_ECO24 - Serine--tRNA ligase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=serS PE=3 SV=1
SYS_ECOL5 - Serine--tRNA ligase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=serS PE=3 SV=1
gi|189376450, gi... - gi|189376450|gb|EDU94866.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC508], gi|16880142...
SYS_SHIF8 - Serine--tRNA ligase OS=Shigella flexneri serotype 5b (strain 8401) GN=serS PE=3 SV=1
SYS_ECODH - Serine--tRNA ligase OS=Escherichia coli (strain K12 / DH10B) GN=serS PE=3 SV=1
SYS_ECOSM - Serine--tRNA ligase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=serS PE=3 SV=1
gi|191167614, gi... - gi|75229261|ref|ZP_00715826.1| COG0172: Seryl-tRNA synthetase [Escherichia coli B7A], gi|191167614|r...
gi|195939556 - gi|195939556|ref|ZP_03084938.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024]
gi|75240970, gi|... - gi|75240970|ref|ZP_00724859.1| COG0172: Seryl-tRNA synthetase [Escherichia coli F11], gi|191172133|r...
gi|208808989, gi... - gi|208808989|ref|ZP_03251326.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], gi|208...
SYS_ECOHS - Serine--tRNA ligase OS=Escherichia coli O9:H4 (strain HS) GN=serS PE=3 SV=1
gi|89107743, gi|... - gi|89107743|ref|AP_001523.1| seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine [E...
gi|208732184, gi... - gi|208815536|ref|ZP_03256715.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], gi|208...
gi|194413610, gi... - gi|75210418|ref|ZP_00710574.1| COG0172: Seryl-tRNA synthetase [Escherichia coli B171], gi|194428395|...
SYS_ECOUT - Serine--tRNA ligase OS=Escherichia coli (strain UTI89 / UPEC) GN=serS PE=3 SV=1
gi|208822033, gi... - gi|208822033|ref|ZP_03262352.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042], gi|208...
gi|168752125, gi... - gi|188013954|gb|EDU52076.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi|1687521...
gi|189355936, gi... - gi|189355936|gb|EDU74355.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4401], gi|1687569...
gi|168762973, gi... - gi|189366796|gb|EDU85212.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501], gi|1687629...
gi|189361156, gi... - gi|189361156|gb|EDU79575.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi|1687698...
gi|168776256, gi... - gi|187768390|gb|EDU32234.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi|1687762...
EG10947 - seryl-tRNA synthetase / Serine--tRNA ligase; serine hydroxamate resistance
gi|168783803, gi... - gi|188998912|gb|EDU67898.1| seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi|1687838...
SYS_ECOLI - Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS) - Escherichia coli
SYS_ECOL6 - Serine--tRNA ligase OS=Escherichia coli O6 GN=serS PE=3 SV=1
SYS_SHIFL - Serine--tRNA ligase OS=Shigella flexneri GN=serS PE=3 SV=1
gi|24112268, gi|... - gi|24112268|ref|NP_706778.1| seryl-tRNA synthetase [Shigella flexneri 2a str. 301], gi|24051120|gb|A...
gi|254591493, gi... - gi|254792093|ref|YP_003076930.1| seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serin...
SYS_ECOL6 - Serine--tRNA ligase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=serS PE=3 SV=1
gi|254161007, gi... - gi|254161007|ref|YP_003044115.1| seryl-tRNA synthetase [Escherichia coli B str. REL606], gi|25397290...
gi|30040626, gi|... - gi|30062380|ref|NP_836551.1| seryl-tRNA synthetase [Shigella flexneri 2a str. 2457T], gi|30040626|gb...
gi|253325122, gi... - gi|254287815|ref|YP_003053563.1| seryl-tRNA synthetase [Escherichia coli BL21(DE3)], gi|253977122|gb...
SYS_ECO57 - Serine--tRNA ligase OS=Escherichia coli O157:H7 GN=serS PE=3 SV=1
gi|242376708, gi... - gi|251784435|ref|YP_002998739.1| hypothetical protein B21_00904 [Escherichia coli BL21], gi|24237670...
EG10947 - seryl-tRNA synthetase / Serine--tRNA ligase; serine hydroxamate resistance
SYS_ECOBW - Serine--tRNA ligase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=serS PE=3 SV=1
gi|226898327, gi... - gi|237707117|ref|ZP_04537598.1| seryl-tRNA synthetase [Escherichia sp. 3_2_53FAA], gi|226898327|gb|E...
gi|227838892, gi... - gi|227884140|ref|ZP_04001945.1| seryl-tRNA synthetase [Escherichia coli 83972], gi|227838892|gb|EEJ4...
SYS_ECOLC - Serine--tRNA ligase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=serS PE=3 SV=1
SYS_ECOK1 - Serine--tRNA ligase OS=Escherichia coli O1:K1 / APEC GN=serS PE=3 SV=1
gi|124531982, gi... - gi|124531982|ref|ZP_01702041.1| seryl-tRNA synthetase [Escherichia coli B], gi|124498244|gb|EAY45765...
0.0 [20..446] [1..429]
gi|25293153 - pir||H85614 hypothetical protein serS [imported] - Escherichia coli (strain O157:H7, substrain EDL9...
gi|12514055, gi|... - gi|15800756|ref|NP_286770.1| seryl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi|12514055|gb...
0.0 [20..446] [1..429]
gi|45441041, gi|... - gi|45441041|ref|NP_992580.1| seryl-tRNA synthetase [Yersinia pestis biovar Microtus str. 91001], gi|...
gi|22126673, gi|... - gi|22126673|ref|NP_670096.1| seryl-tRNA synthetase [Yersinia pestis KIM], gi|21959689|gb|AAM86347.1|...
gi|16121659, gi|... - gi|218928527|ref|YP_002346402.1| seryl-tRNA synthetase [Yersinia pestis CO92], gi|16121659|ref|NP_40...
SYS_YERPS - Serine--tRNA ligase OS=Yersinia pseudotuberculosis GN=serS PE=3 SV=1
SYS_YERPS - Serine--tRNA ligase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=serS PE=3 SV=1
SYS_YERPG - Serine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=serS PE=3 SV=1
SYS_YERP3 - Serine--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=serS PE=3 SV=1
SYS_YERPE - Serine--tRNA ligase OS=Yersinia pestis GN=serS PE=3 SV=1
gi|229841348, gi... - gi|229841348|ref|ZP_04461507.1| Seryl-tRNA synthetase [Yersinia pestis biovar Orientalis str. PEXU2]...
gi|229843453, gi... - gi|229843453|ref|ZP_04463599.1| Seryl-tRNA synthetase [Yersinia pestis biovar Orientalis str. India ...
gi|229895825, gi... - gi|229895825|ref|ZP_04510995.1| Seryl-tRNA synthetase [Yersinia pestis Pestoides A], gi|229700748|gb...
SYS_YERPY - Serine--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=serS PE=3 SV=1
SYS_YERPB - Serine--tRNA ligase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=serS PE=3 SV=1
gi|89105522, gi|... - gi|89105522|ref|ZP_01178040.1| COG0172: Seryl-tRNA synthetase [Yersinia pestis biovar Orientalis str...
SYS_YERPA - Serine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=serS PE=3 SV=1
SYS_YERPN - Serine--tRNA ligase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=serS PE=3 SV=1
gi|165924544, gi... - gi|165924544|ref|ZP_02220376.1| seryl-tRNA synthetase [Yersinia pestis biovar Orientalis str. F19910...
gi|149366636, gi... - gi|149366636|ref|ZP_01888670.1| seryl-tRNA synthetase [Yersinia pestis CA88-4125], gi|149291010|gb|E...
gi|166009792, gi... - gi|166009792|ref|ZP_02230690.1| seryl-tRNA synthetase [Yersinia pestis biovar Antiqua str. E1979001]...
SYS_YERPP - Serine--tRNA ligase OS=Yersinia pestis (strain Pestoides F) GN=serS PE=3 SV=1
gi|166211248, gi... - gi|166211248|ref|ZP_02237283.1| seryl-tRNA synthetase [Yersinia pestis biovar Antiqua str. B42003004...
gi|167400076, gi... - gi|167400076|ref|ZP_02305594.1| seryl-tRNA synthetase [Yersinia pestis biovar Antiqua str. UG05-0454...
gi|166962445, gi... - gi|167419704|ref|ZP_02311457.1| seryl-tRNA synthetase [Yersinia pestis biovar Orientalis str. MG05-1...
gi|167056885, gi... - gi|167424036|ref|ZP_02315789.1| seryl-tRNA synthetase [Yersinia pestis biovar Mediaevalis str. K1973...
0.0 [20..446] [1..429]

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Predicted Domain #1
Region A:
Residues: [1-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIRRLFSIS NRSFFLKKPQ FDVKKIIEMI PQYQTSIQNR ELIEADSIIR SLQLLGERYQ  60
   61 NIKEIDKVIA DIQIQRKSIE AQIKKDKTKI TEYSAALKAL KEQYNDQNSK SSELKKKILE 120
  121 TCKSLPNTLD PTVPLDAPQI EQWINPLKTH KTSEAQAHVD IMLKKNMLDL QTASNVTGMS 180
  181 WYYLLNDGAR LEQALVAYAL KKANENGFSS CVPPSITKKE LIDACGFNPR DMNNERQIYA 240
  241 LQDTNLGLVA TAEIPLAGLG ANKVLELNSG ECSKKLVGVS RCYRAEAGAR GKDTKGLYRV 300
  301 HEFTKVELFC WSKPETSAKV LEEIKQFQIS VVEELGIPAK VLNMPSNDLG NPAFKKYDIE 360
  361 AWMPGRGKFG EISSASNCTD FQSRRLNTKY RDDNTGKLEY VHTLNGTAMA IPRVIVALVE 420
  421 NFYDPSTGKI SVPECLREFM NGQRYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 435.9897
Match: 1serA_
Description: Seryl-tRNA synthetase (SerRS)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle