YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: COS8
Organism: Saccharomyces cerevisiae
Length: 381 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS8.

Description E-value Query
Range
Subject
Range
COS1 - Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-enc...
COS1_YEAST - Protein COS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS1 PE=1 SV=1
597.0 [0..1] [380..1]

Back

Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENEVKDEK SVDVLSFKQL EFQKTVLPQD VFRNELTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.578 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.472 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.282 N/A N/A a.4.1 Homeodomain-like

Predicted Domain #2
Region A:
Residues: [62-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSSNWIH PLIVSLLVLF LGPFFVLVIC GLSRKRSLSK QLIQFCKEIT EDTPSSDPHD  60
   61 WEVVAANLNS YFYENKTWNT KYFFFNAMSC QKAFKTTLLE PFSLKKD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 49.309804
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.820 N/A N/A a.64.1 Saposin
View Download 0.781 N/A N/A a.186.1 Description not found.
View Download 0.753 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.753 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.745 N/A N/A a.186.1 Description not found.
View Download 0.660 N/A N/A a.216.1 Description not found.
View Download 0.648 N/A N/A a.8.9 Description not found.
View Download 0.581 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.570 N/A N/A a.19.1 Fertilization protein
View Download 0.536 N/A N/A a.29.2 Bromodomain

Predicted Domain #3
Region A:
Residues: [169-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESAKVKSFKD SVPYIEEALQ VYAAGFDKEW KLFNTEKEES PFDLEDIQLP KEAYRFKLTW  60
   61 ILKRIFNLRC L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.585 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.450 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.449 a.37.1 A DNA-binding domain in eukaryotic transcription factors

Predicted Domain #4
Region A:
Residues: [240-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLFLYYFLIV YTSGNADLIS RFLFPVVMFF IMTRDFQNMR MIVLSVKMEH KMQFLSTIIN  60
   61 EQESGANGWD EIAKKMNRYL FEKKVWNNEE FFYDGLDCEW FFRRFFYRLL SLKKPMWFAS 120
  121 LNVELWPYIK EAQSARNEKP LK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.79588
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.724 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.724 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.625 N/A N/A c.56.5 Zn-dependent exopeptidases
View Download 0.592 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.558 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.556 N/A N/A a.118.1 ARM repeat
View Download 0.556 N/A N/A a.118.22 Description not found.
View Download 0.438 N/A N/A c.47.1 Thioredoxin-like
View Download 0.426 N/A N/A c.23.5 Flavoproteins


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle