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View Structure Prediction Details

Protein: YHL018W
Organism: Saccharomyces cerevisiae
Length: 120 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHL018W.

Description E-value Query
Range
Subject
Range
gi|190405764 - gi|190405764|gb|EDV09031.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|151944182 - gi|151944182|gb|EDN62474.1| conserved protein [Saccharomyces cerevisiae YJM789]
PHS_YEAST - Putative pterin-4-alpha-carbinolamine dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
YHL018W - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mi...
1.0E-32 [1..120] [1..120]
CE18240 - WBGene00020397 locus:pcbd-1 status:Partially_confirmed
8.0E-31 [7..116] [78..177]
PHS_MOUSE - Pterin-4-alpha-carbinolamine dehydratase OS=Mus musculus GN=Pcbd1 PE=1 SV=2
1.0E-30 [8..119] [3..104]
gi|114631016 - gi|114631016|ref|XP_001171466.1| PREDICTED: similar to PCBD1 protein [Pan troglodytes]
PCBD1 - pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
gi|208967210 - gi|208967210|dbj|BAG73619.1| pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepat...
gi|194042768 - gi|194042768|ref|XP_001928236.1| PREDICTED: similar to pterin-4 alpha-carbinolamine dehydratase/dime...
gi|109089412 - gi|109089412|ref|XP_001107537.1| PREDICTED: similar to Pterin-4-alpha-carbinolamine dehydratase (PHS...
ENSCJAT00000028755 - null
PHS_RAT - Pterin-4-alpha-carbinolamine dehydratase OS=Rattus norvegicus GN=Pcbd1 PE=1 SV=2
2.0E-30 [8..119] [3..104]
PHS_XENLA - Pterin-4-alpha-carbinolamine dehydratase OS=Xenopus laevis GN=pcbd PE=3 SV=3
3.0E-30 [8..119] [3..104]
PHS_CHICK - Pterin-4-alpha-carbinolamine dehydratase OS=Gallus gallus GN=PCBD1 PE=2 SV=3
3.0E-30 [8..119] [3..104]
gi|1943051, gi|1... - gi|1943051|pdb|1DCP|G Chain G, Dcoh, A Bifunctional Protein-Binding Transcriptional Coactivator, Com...
4.0E-30 [8..118] [3..103]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNKIVRIAS SALTGGKLLE KLKPLTRWEV QWDPNKTKCL GITREVTFKD YETTWAFLTR  60
   61 VSMRSHLWGH HPLIHTSYTW VKLELHTHDI DPKDGAHSQL SDIDVRMAKR IDSYIDEMTT 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.211549
Match: 1dchA_
Description: Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.633249790434806 bayes_pls_golite062009
binding 0.109738634058146 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle