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View Structure Prediction Details

Protein: PRS3
Organism: Saccharomyces cerevisiae
Length: 320 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS3.

Description E-value Query
Range
Subject
Range
PRPS1 - phosphoribosyl pyrophosphate synthetase 1
gi|208967042, gi... - gi|208967042|dbj|BAG73535.1| phosphoribosyl pyrophosphate synthetase 1-like 1 [synthetic construct],...
ENSCJAT00000043257 - null
gi|114689771, gi... - gi|114689771|ref|XP_001144504.1| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi|114...
PRPS1_PONAB - Ribose-phosphate pyrophosphokinase 1 OS=Pongo abelii GN=PRPS1 PE=2 SV=1
tr|M3WGN3|M3WGN3... - Phosphoribosyl pyrophosphate synthetase 1 OS=Felis catus GN=PRPS1 PE=3 SV=1
PRPS1_PONPY - Ribose-phosphate pyrophosphokinase I - Pongo pygmaeus (Orangutan)
gi|109131827 - gi|109131827|ref|XP_001095604.1| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phospho...
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=4
PRPS1_BOVIN - Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus GN=PRPS1 PE=2 SV=3
gi|74008042 - gi|74008042|ref|XP_850853.1| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribo...
PRPS1_RAT - Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2
0.0 [3..320] [1..318]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3
0.0 [3..320] [1..318]
tr|G3I9Z3|G3I9Z3... - Ribose-phosphate pyrophosphokinase 2 OS=Cricetulus griseus GN=I79_020407 PE=3 SV=1
PRPS2_RAT - Ribose-phosphate pyrophosphokinase 2 OS=Rattus norvegicus GN=Prps2 PE=1 SV=3
0.0 [3..320] [1..318]
gi|54641819, gi|... - gi|54641819|gb|EAL30569.1| GA19849-PA [Drosophila pseudoobscura], gi|125978070|ref|XP_001353068.1| G...
gi|220948594, gi... - gi|220958100|gb|ACL91593.1| CG6767-PA [synthetic construct], gi|220948594|gb|ACL86840.1| CG6767-PA [...
FBpp0311282, CG6... - This gene is referred to in FlyBase by the symbol Dmel\CG6767 (CG6767, FBgn0036030). It is a protein...
0.0 [3..319] [33..349]
KPRS1_SPIOL - Ribose-phosphate pyrophosphokinase 1 OS=Spinacia oleracea GN=PRS1 PE=2 SV=1
5.0E-99 [2..316] [22..336]
CE00745 - Ribose-phosphate pyrophosphokinase status:Confirmed UniProt:Q21994 protein_id:AAK29853.1
6.0E-99 [3..320] [59..376]
KPRS2_ARATH - Ribose-phosphate pyrophosphokinase 2, chloroplastic OS=Arabidopsis thaliana GN=PRS2 PE=2 SV=2
8.0E-99 [2..315] [86..399]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTNSIKLLA PDVHRGLAEL VAKRLGLQLT SSKLKRDPTG EVSFSIGESV RDQDIFIITQ  60
   61 IGSGVVNDRV LELLIMINAS KTASARRITA IIPNFPYARQ DRKDKSRAPI TAKLMADMLT 120
  121 TAGCDHVITM DLHASQIQGF FDVPVDNL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [295-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVLAESIRR LHNGESISYL FKNYPL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 763.9794
Match: 1dkrA_
Description: Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [149-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAEPSVVRYI KENVNYMDSI IISPDAGGAK RAATLADRLD LNFALIHKER ARANEVSRMV  60
   61 LVGDVTDKIC IIVDDMADTC GTLAKAAEIL LENRAKSVIA IVTHGVLSGR AIENINNSKL 120
  121 DRVVCTNTVP FEEKIKKCPK LAVIDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 763.9794
Match: 1dkrA_
Description: Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle