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View Structure Prediction Details

Protein: HSV2
Organism: Saccharomyces cerevisiae
Length: 448 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSV2.

Description E-value Query
Range
Subject
Range
gi|17225204 - gi|17225204|gb|AAL37298.1|AF323582_1 beta transducin-like protein HET-E2C [Podospora anserina]
0.0 [8..447] [833..1255]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..448] [1060..1490]

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Predicted Domain #1
Region A:
Residues: [1-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVRRPIREA VNNRRKPKFL SVSFNQDDSC FSVALENGFR IFNTDPLTSK LSKTFKESAT  60
   61 NQSRGTGIGY TRMLYRTNYI ALVGGGKRPR HALNKLIIWD DLLQKETITL KFMSSIKDVF 120
  121 LSRIHIVVVL ENTIEIFQFQ TNPQRICPIL DIPPNGSVDY VVCSSKHLQS QASQSQSKIL 180
  181 EIIAFPSNKC VGQIQVADLS QIKYNSQNPK ESALLPTSII KAHKNPIKLV RLNRQGTMVA 240
  241 TCSVQGTLIR IFSTHNGTLI KEFRRGVDKA DIYEMSFSPN GSKLAVLSNK QTLHIFQIFE 300
  301 TTNTETNTPD HSRANGSSHP LKNYIPKGLW RPKYLDSVWS ICNAHLKNPI FDAHRNDNSG 360
  361 DVTHDNEFYK DRCRIGWCQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.30103
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [380-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNNREQDDS LVLVWQNSGI WEKFVILEKE QQDSSKTHYS LNESLRNEDT KSAGEPTRWE  60
   61 LVRESWREL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.737 a.4.1 Homeodomain-like
View Download 0.574 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.679 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.739 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.559 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.511 a.7.7 BAG domain
View Download 0.474 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.451 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.429 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.427 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.424 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.405 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.392 d.58.17 Metal-binding domain
View Download 0.388 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.371 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.359 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.354 a.77.1 DEATH domain
View Download 0.350 a.159.2 FF domain
View Download 0.344 a.60.1 SAM/Pointed domain
View Download 0.335 a.4.5 "Winged helix" DNA-binding domain
View Download 0.320 a.60.12 DNA polymerase beta-like, second domain
View Download 0.310 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.309 a.144.1 PABC (PABP) domain
View Download 0.296 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.290 a.60.2 RuvA domain 2-like
View Download 0.290 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.290 a.3.1 Cytochrome c
View Download 0.289 a.51.1 Cytochrome c oxidase subunit h
View Download 0.282 a.3.1 Cytochrome c
View Download 0.273 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.272 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.268 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.262 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.257 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.257 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.254 a.61.1 Retroviral matrix proteins
View Download 0.245 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.243 a.28.1 ACP-like
View Download 0.237 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.236 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.231 a.150.1 Anti-sigma factor AsiA
View Download 0.225 c.47.1 Thioredoxin-like
View Download 0.220 a.77.1 DEATH domain
View Download 0.213 a.4.1 Homeodomain-like
View Download 0.207 a.8.1 Bacterial immunoglobulin/albumin-binding domains


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle