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View Structure Prediction Details

Protein: LSB1
Organism: Saccharomyces cerevisiae
Length: 241 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LSB1.

Description E-value Query
Range		 Subject
Range
gi|151943416 - gi|151943416|gb|EDN61727.1| Las17p binding protein [Saccharomyces cerevisiae YJM789]
LSB1 - Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldri...
gi|190406846 - gi|190406846|gb|EDV10113.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
LSB1_YEAST - LAS seventeen-binding protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LSB1 PE=...
 6.0E-49 [1..241] [1..241]
ITN1_MOUSE, ITSN... - Intersectin-1 OS=Mus musculus GN=Itsn1 PE=1 SV=1, (Q9Z0R4) Intersectin 1 (EH and SH3 domains protein...
 1.0E-34 [6..202] [682..912]
gi|17980553 - gi|17980553|gb|AAL50641.1|AF440203_1 Crk-based reporter [synthetic construct]
 8.0E-32 [5..172] [321..469]
ITSN1 - intersectin 1 (SH3 domain protein)
 1.0E-31 [6..202] [684..919]
CSH3_SCHPO - Protein csh3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=csh3 PE=2 SV=1
SPBC119.05c - Wiskott-Aldrich syndrome homolog binding protein Lsb1
 2.0E-30 [1..241] [86..296]
gi|14009490, gi|... - gi|47481728|gb|AAH70877.1| SH3-domain kinase binding protein 1 [Rattus norvegicus], gi|29789297|ref|...
 5.0E-30 [11..220] [229..446]

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Predicted Domain #1
Region A:
Residues: [1-110] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLVNRSL KNIRNELEFL KESNVISGDI FELINSKLPE KWDGNQRSPQ NADTEEYVEA  60
   61 LYDFEAQQDG DLSLKTGDKI QVLEKISPDW YRGKSNNKIG IFPANYVKPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 132.67837
Match: 1griA_
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [111-241] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTRSASPKSA EAASSSTVSR PSVPPPSYEP AASQYPSQQV SAPYAPPAGY MQAPPPQQQQ  60
   61 APLPYPPPFT NYYQQPQQQY APPSQQAPVE AQPQQSSGAS SAFKSFGSKL GNAAIFGAGS 120
  121 AIGSDIVNSI F

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.34
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle