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View Structure Prediction Details

Protein: RSC1
Organism: Saccharomyces cerevisiae
Length: 928 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSC1.

Description E-value Query
Range
Subject
Range
RSC1 - Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-s...
RSC1_YEAST - Chromatin structure-remodeling complex subunit RSC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 ...
0.0 [1..928] [1..928]
gi|12083892, gi|... - gi|30794372|ref|NP_060635.2| polybromo 1 isoform 1 [Homo sapiens], gi|12083892|gb|AAG48939.1|AF22587...
2.0E-85 [10..541] [488..1092]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-82 [10..537] [518..1118]
rsc1 - RSC complex subunit Rsc1
RSC1_SCHPO - Chromatin structure-remodeling complex subunit rsc1 OS=Schizosaccharomyces pombe (strain 972 / ATCC ...
1.0E-74 [9..579] [14..560]
polybromo-PA - The gene polybromo is referred to in FlyBase by the symbol Dmel\polybromo (CG11375, FBgn0039227). It...
6.0E-66 [7..531] [510..1086]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEQDNGFLQ KLLKTQYDAV FHLKDENGIE IYPIFNVLPP KKEYPDYYII IRNPISLNTL  60
   61 KKRLPHYTSP QDFVNDFAQI PWNAMTY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.751666
Match: 1e6iA_
Description: GCN5
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [88-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAKDSVIYKY AILLESFIKG KIVHNIRKHY PEVTYPSLGR IPEIFAESMQ PSDLSSNPIN  60
   61 TQENDEKAGL NPEMKMAFAK LDSSITERKP TNQDYRMQQK NSPAFPTHSA SITPQPLASP 120
  121 TPVVNYANIT SAHPKTHVRR GRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.917458
Match: 1eqfA_
Description: TAFII250 double bromodomain module
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [231-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVIDLPYVLR IKNILKMMRR EVDQNNKTLT LCFEKLPDRN EEPTYYSVIT DPICLMDIRK  60
   61 KVKSRKYRNF HTFEEDFQLM LTNFKLYYSQ DQSNIIRAQL LEKNFNRLVR IELSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.917458
Match: 1eqfA_
Description: TAFII250 double bromodomain module
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [346-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDEDYLPEGE LRYPLDDVEI NDEKYQIGDW VLLHNPNDIN KPIVGQIFRL WSTTDGNKWL  60
   61 NACWYFRPEQ TVHRVDRLFY KNEVMKTGQY RDHPIQDIKG KCYVIHFTRF QRGDPSTKVN 120
  121 GPQFVCEFRY NESDKVFNKI RTWKACLPEE LRDQDEPTIP VNGRKFFKYP SPIADLLPAN 180
  181 ATLNDKVPEP TEG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.88
Match: 1m4zA
Description: Origin-recognition complect protein 120kDa subunit, Orc1p
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [539-697]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APTAPPLVGA VYLGPKLERD DLGEYSTSDD CPRYIIRPND PPEEGKIDYE TGTIITDTLT  60
   61 TSSMPRVNSS STIRLPTLKQ TKSIPSSNFR SSSNTPLLHQ NFNQTSNFLK LENMNNSSHN 120
  121 LLSHPSVPKF QSPSLLEQSS RSKYHSAKKQ TQLSSTAPK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [698-928]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPASKSFTLS SMINTLTAHT SKYNFNHIVI EAPGAFVVPV PMEKNIRTIQ STERFSRSNL  60
   61 KNAQNLGNTA INDINTANEQ IIWFKGPGVK ITERVIDSGN DLVRVPLNRW FCKNKRRKLD 120
  121 YEDIEEDVME PPNDFSEDMI ANIFNPPPSL NLDMDLNLSP SSNNSSNFMD LSTIASGDND 180
  181 GKECDTAEES EDENEDTEDE HEIEDIPTTS AFGLNSSAEY LAFRLREFNK L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle