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View Structure Prediction Details

Protein: COS12
Organism: Saccharomyces cerevisiae
Length: 380 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS12.

Description E-value Query
Range
Subject
Range
COS5 - Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encode...
COS5_YEAST - Protein COS5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS5 PE=1 SV=1
0.0 [5..379] [7..377]

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Predicted Domain #1
Region A:
Residues: [1-59]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGAKFENTV AFLPSEIFDC YNSTLPKNVF RSFVTWSCYE KFNSLEFRTW LLMWLPLII

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [60-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWKIRGKRHY LVIVTALMFE VLYFLWTYSY IFRERTLGKQ VSQFAKEIIT NTPGIDTEDW  60
   61 ERVAVNFNSY LYENKLWNTE YFFFDGSSCQ EAFRKMLLEP FSLKKNDFAN AK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 47.677781
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.934 N/A N/A a.24.17 Group V grass pollen allergen

Predicted Domain #3
Region A:
Residues: [172-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPDGSVCYTE KALQVYFTQI ERKWHWINSE GFLHNKTTQS VQFSKHGYGS KLLWAFKEVT  60
   61 IMNSRFAFFS IAYLN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [247-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLLTIPRLRN SLHILYVCAV LSSMIIEYLI GIDKFRFKSM NLIHKLQFLS YITCGHEKSD  60
   61 ATNWSQIAKR TNTYMFEQKI WNSPILFSDG IDCEKFFKWY FSTPVSSQAS LSVGSTDFEL 120
  121 WPYIKEAQSA CNDV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.065502
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle