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View Structure Prediction Details

Protein: KAP114
Organism: Saccharomyces cerevisiae
Length: 1004 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAP114.

Description E-value Query
Range
Subject
Range
gi|162318534 - gi|162318534|gb|AAI56332.1| Importin 9 [synthetic construct]
IPO9 - importin 9
gi|114571796 - gi|114571796|ref|XP_514097.2| PREDICTED: importin 9 [Pan troglodytes]
ENSCJAT00000010986 - null
0.0 [3..999] [25..1036]
IPO9_MOUSE - Importin-9 OS=Mus musculus GN=Ipo9 PE=1 SV=3
0.0 [3..999] [25..1036]
KAP114 - Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino termin...
IMB5_YEAST - Importin subunit beta-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP114 PE=1 SV=1
0.0 [1..1004] [1..1004]
XPO2_PAGMA - Exportin-2 OS=Pagrus major GN=cse1l PE=2 SV=1
0.0 [3..846] [11..859]

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Predicted Domain #1
Region A:
Residues: [1-704]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDINELIIGA QSADKHTREV AETQLLQWCD SDASQVFKAL ANVALQHEAS LESRQFALLS  60
   61 LRKLITMYWS PGFESYRSTS NVEIDVKDFI REVLLKLCLN DNENTKIKNG ASYCIVQISA 120
  121 VDFPDQWPQL LTVIYDAISH QHSLNAMSLL NEIYDDVVSE EMFFEGGIGL ATMEIVFKVL 180
  181 NTETSTLIAK IAALKLLKAC LLQMSSHNEY DEASRKSFVS QCLATSLQIL GQLLTLNFGN 240
  241 VDVISQLKFK SIIYENLVFI KNDFSRKHFS SELQKQFKIM AIQDLENVTH INANVETTES 300
  301 EPLLETVHDC SIYIVEFLTS VCTLQFSVEE MNKIITSLTI LCQLSSETRE IWTSDFNTFV 360
  361 SKETGLAASY NVRDQANEFF TSLPNPQLSL IFKVVSNDIE HSTCNYSTLE SLLYLLQCIL 420
  421 LNDDEITGEN IDQSLQILIK TLENILVSQE IPELILARAI LTIPRVLDKF IDALPDIKPL 480
  481 TSAFLAKSLN LALKSDKELI KSATLIAFTY YCYFAELDSV LGPEVCSETQ EKVIRIINQV 540
  541 SSDAEEDTNG ALMEVLSQVI SYNPKEPHSR KEILQAEFHL VFTISSEDPA NVQVVVQSQE 600
  601 CLEKLLDNIN MDNYKNYIEL CLPSFINVLD SNNANNYRYS PLLSLVLEFI TVFLKKKPND 660
  661 GFLPDEINQY LFEPLAKVLA FSTEDETLQL ATEAFSYLIF NTDT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [705-915]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RAMEPRLMDI MKVLERLLSL EVSDSAAMNV GPLVVAIFTR FSKEIQPLIG RILEAVVVRL  60
   61 IKTQNISTEQ NLLSVLCFLT CNDPKQTVDF LSSFQIDNTD ALTLVMRKWI EAFEVIRGEK 120
  121 RIKENIVALS NLFFLNDKRL QKVVVNGNLI PYEGDLIITR SMAKKMPDRY VQVPLYTKII 180
  181 KLFVSELSFQ SKQPNPEQLI TSDIKQEVVN A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [916-1004]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKDDDNDDWE DVDDVLDYDK LKEYIDDDVD EEADDDSDDI TGLMDVKESV VQLLVRFFKE  60
   61 VASKDVSGFH CIYETLSDSE RKVLSEALL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.721 a.47.2 t-snare proteins
View Download 0.627 a.7.7 BAG domain
View Download 0.592 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.665 a.47.2 t-snare proteins
View Download 0.586 i.1.1 Ribosome and ribosomal fragments
View Download 0.579 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.505 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.471 a.46.1 Methionine synthase domain
View Download 0.467 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.460 f.15.1 Small-conductance potassium channel
View Download 0.444 a.22.1 Histone-fold
View Download 0.424 a.2.7 tRNA-binding arm
View Download 0.421 a.1.1 Globin-like
View Download 0.414 a.24.3 Cytochromes
View Download 0.413 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.411 a.24.12 Outer surface protein C (OspC)
View Download 0.407 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.404 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.398 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.389 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.388 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.378 a.39.1 EF-hand
View Download 0.376 a.24.3 Cytochromes
View Download 0.372 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.368 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.365 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.363 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.359 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.356 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.346 a.112.1 Description not found.
View Download 0.346 a.7.1 Spectrin repeat
View Download 0.344 a.22.1 Histone-fold
View Download 0.342 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.338 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.337 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.331 a.7.8 GAT domain
View Download 0.329 a.22.1 Histone-fold
View Download 0.329 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.326 a.47.2 t-snare proteins
View Download 0.324 a.112.1 Description not found.
View Download 0.321 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.321 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.320 a.7.5 Tubulin chaperone cofactor A
View Download 0.318 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.313 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.311 a.7.1 Spectrin repeat
View Download 0.308 a.7.8 GAT domain
View Download 0.305 i.11.1 Computational models partly based on NMR data
View Download 0.303 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.303 a.22.1 Histone-fold
View Download 0.302 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.302 a.24.3 Cytochromes
View Download 0.301 a.47.2 t-snare proteins
View Download 0.297 a.7.7 BAG domain
View Download 0.294 a.2.3 Chaperone J-domain
View Download 0.292 a.60.1 SAM/Pointed domain
View Download 0.285 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.283 a.74.1 Cyclin-like
View Download 0.277 a.4.5 "Winged helix" DNA-binding domain
View Download 0.276 a.24.3 Cytochromes
View Download 0.273 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.268 a.74.1 Cyclin-like
View Download 0.267 a.1.1 Globin-like
View Download 0.266 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.264 a.24.3 Cytochromes
View Download 0.264 a.4.1 Homeodomain-like
View Download 0.264 a.74.1 Cyclin-like
View Download 0.263 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.261 a.112.1 Description not found.
View Download 0.260 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.255 a.7.8 GAT domain
View Download 0.252 a.22.1 Histone-fold
View Download 0.250 i.1.1 Ribosome and ribosomal fragments
View Download 0.249 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.248 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.244 a.47.2 t-snare proteins
View Download 0.243 a.47.2 t-snare proteins
View Download 0.241 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.240 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.240 a.7.1 Spectrin repeat
View Download 0.239 a.1.1 Globin-like
View Download 0.238 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.233 a.95.1 Influenza virus matrix protein M1
View Download 0.232 d.42.1 POZ domain
View Download 0.228 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.227 a.25.1 Ferritin-like
View Download 0.225 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.223 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.222 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.219 a.71.2 Helical domain of Sec23/24
View Download 0.219 a.2.7 tRNA-binding arm
View Download 0.217 a.7.7 BAG domain
View Download 0.216 a.81.1 N-terminal domain of DnaB helicase
View Download 0.216 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.215 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.214 i.11.1 Computational models partly based on NMR data
View Download 0.211 a.74.1 Cyclin-like
View Download 0.211 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.211 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.210 i.11.1 Computational models partly based on NMR data
View Download 0.208 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.208 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.208 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.208 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.207 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.205 a.26.1 4-helical cytokines
View Download 0.205 a.47.2 t-snare proteins
View Download 0.205 a.118.1 ARM repeat
View Download 0.204 a.85.1 Hemocyanin, N-terminal domain
View Download 0.204 a.36.1 Signal peptide-binding domain
View Download 0.203 a.2.3 Chaperone J-domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle