YRC Public Data Repository - Protein Structure Prediction

Protein:	TAN1
Organism:	Saccharomyces cerevisiae
Length:	289 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAN1.

Description	E-value	Query Range	Subject Range
gi\|190407166 - gi\|190407166\|gb\|EDV10433.1\| tRNA acetyltransferase TAN1 [Saccharomyces cerevisiae RM11-1a] TAN1_YEAST - tRNA acetyltransferase TAN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAN1 PE=1 SV... TAN1 - Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucl...	1.0E-80	[1..289]	[1..289]
THUM1_MOUSE - THUMP domain-containing protein 1 OS=Mus musculus GN=Thumpd1 PE=1 SV=1	3.0E-54	[27..280]	[39..273]
CE18316 - status:Predicted UniProt:O61900 protein_id:AAC17683.1	2.0E-52	[1..272]	[76..337]
CG15014-PA - This gene is referred to in FlyBase by the symbol Dmel\CG15014 (CG15014, FBgn0035532). It is a prote... gi\|220950056, gi... - gi\|220959070\|gb\|ACL92078.1\| CG15014-PA [synthetic construct], gi\|220950056\|gb\|ACL87571.1\| CG15014-PA...	1.0E-51	[2..283]	[4..282]
gi\|42561854, gi\|... - gi\|42561854\|ref\|NP_172400.2\| unknown protein [Arabidopsis thaliana], gi\|14334964\|gb\|AAK59659.1\| unkn...	4.0E-47	[17..249]	[46..304]
gi\|2988398 - gi\|2988398\|gb\|AAC31666.1\| Unknown gene product [Homo sapiens]	1.0E-35	[108..282]	[1..164]
THII_PASMU - tRNA sulfurtransferase OS=Pasteurella multocida (strain Pm70) GN=thiI PE=3 SV=1 THII_PASMU - tRNA sulfurtransferase OS=Pasteurella multocida GN=thiI PE=3 SV=1	4.0E-33	[104..255]	[14..161]
gi\|213427860 - gi\|213427860\|ref\|ZP_03360610.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... THII_SALTI - tRNA sulfurtransferase OS=Salmonella typhi GN=thiI PE=3 SV=1 gi\|213052897 - gi\|213052897\|ref\|ZP_03345775.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... THII_SALTI - Thiamine biosynthesis protein thiI OS=Salmonella typhi GN=thiI PE=3 SV=1 gi\|214000382 - gi\|214000382\|ref\|ZP_03411117.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|213855373 - gi\|213855373\|ref\|ZP_03383613.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|29142826, gi\|... - gi\|29142826\|ref\|NP_806168.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enterica... gi\|213647261 - gi\|213647261\|ref\|ZP_03377314.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|16759402 - gi\|16759402\|ref\|NP_455019.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enterica... gi\|213585097 - gi\|213585097\|ref\|ZP_03366923.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter...	1.0E-32	[104..263]	[14..167]
lcl\|NC_016856.1_... - [gene=thiI] [protein=thiamine biosynthesis protein ThiI] [protein_id=YP_005236118.1] [location=47856... THII_SALTY - tRNA sulfurtransferase OS=Salmonella typhimurium GN=thiI PE=3 SV=2 THII_SALTY - Thiamine biosynthesis protein thiI OS=Salmonella typhimurium GN=thiI PE=3 SV=2 THII_SALTY - tRNA sulfurtransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=thiI PE=3 ... gi\|205329560, gi... - gi\|205329560\|gb\|EDZ16324.1\| thiamine biosynthesis/tRNA modification protein ThiI [Salmonella enteric...	1.0E-32	[104..263]	[14..167]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEKRNRNGK DANSQNRKKF KVSSGFLDPG TSGIYATCSR RHERQAAQEL QLLFEEKFQE  60
   61 LYGDIKEGED ESENDEKKDL SIEDQIKKEL QELKGEETGK D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [102-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSSGETKKKD PLAFIDLNCE CVTFCKTRKP IVPEEFVLSI MKDLADPKNM VKRTRYVQKL  60
   61 TPITYSCNAK MEQLIKLANL VIGPHFHDPS NVKKNYKFAV EVTRRNFNTI ERMDIINQVV 120
  121 KLVNKEGSEF NHTVDLKNYD KLILVECFKS NIGMCVVDGD YKTKYRKYNV QQLYESKFRK 180
  181 DEDKSVKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	22.886057
Match:	PF02926
Description:	THUMP domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.364912245438605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: