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View Structure Prediction Details

Protein: SPT16
Organism: Saccharomyces cerevisiae
Length: 1035 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPT16.

Description E-value Query
Range
Subject
Range
SPT16 - Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which associates with chromatin via intera...
SPT16_YEAST - FACT complex subunit SPT16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPT16 PE=1 SV...
0.0 [1..1035] [1..1035]
SUPT16H - suppressor of Ty 16 homolog (S. cerevisiae)
gi|114651875 - gi|114651875|ref|XP_528703.2| PREDICTED: similar to chromatin-specific transcription elongation fact...
gi|208967510 - gi|208967510|dbj|BAG73769.1| suppressor of Ty 16 homolog [synthetic construct]
0.0 [4..1028] [3..1001]
gi|15637171, gi|... - gi|15809048|ref|NP_291096.1| suppressor of Ty 16 homolog [Mus musculus], gi|15637171|gb|AAL04452.1|A...
0.0 [4..1028] [3..1001]
CC68_KLULA, CDC6... - FACT complex subunit SPT16 OS=Kluyveromyces lactis GN=SPT16 PE=3 SV=2, (Q00976) Cell division contro...
SPT16_KLULA - FACT complex subunit SPT16 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1...
0.0 [1..1035] [1..1033]
gi|147903310, gi... - gi|4586287|dbj|BAA76334.1| DUF140 [Xenopus laevis], gi|147903310|ref|NP_001084166.1| DUF140 [Xenopus...
0.0 [4..1035] [3..1010]
spt16 - FACT complex component Spt16
SPT16_SCHPO - FACT complex subunit spt16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spt16 PE=1 SV=1
0.0 [1..1035] [1..1011]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [40..975] [7..910]
gi|12082670 - gi|12082670|gb|AAG48574.1|AF253047_2 large subunit Cp complex Cdc68p [Candida albicans]
0.0 [1..1033] [1..1051]
SPT16_ARATH - FACT complex subunit SPT16 OS=Arabidopsis thaliana GN=SPT16 PE=1 SV=1
0.0 [4..1034] [24..1032]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEELNIDFDV FKKRIELLYS KYNEFEGSPN SLLFVLGSSN AENPYQKTTI LHNWLLSYEF  60
   61 PATLIALVPG KVIIITSSAK AKHLQKAIDL FKDPESKITL ELWQRNNKEP ELNKKLFDDV 120
  121 IALINSAGKT VGIPEKDSYQ GKFMTEWNPV WEAAVKENEF NVIDISLGLS K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.045757
Match: 1az9__
Description: Aminopeptidase P; Aminopeptidase P, C-terminal domain

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.3228898238998 bayes_pls_golite062009
DNA binding 1.6830709273154 bayes_pls_golite062009
nucleic acid binding 1.67660713848062 bayes_pls_golite062009
binding 1.4562583231987 bayes_pls_golite062009
transcription factor activity 1.02226978078776 bayes_pls_golite062009
protein binding 0.170797254754318 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [172-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VWEVKDVNEQ AFLSVSSKGS DKFMDLLSNE MVRAVDEELK ITNAKLSDKI ENKIDDVKFL  60
   61 KQLSPDLSAL CPPNYKFNFD LLDWTYSPII QSGKKFDLRV SARSTNDQLY GNGCILASCG 120
  121 IRYNNYCSNI TRTFLIDPSE EMANNYDFLL TLQKEIVTNI LKPGRTPKEV YESVIEYIEK 180
  181 TKPELVPNFT KNIGSLIGLE FRDSNFILNV KNDYRKIQRG DCFNISFGFN NLKDSQSANN 240
  241 YALQLADTVQ IPLDETEPPR FLTNYTKAKS QISFYFNNEE EDNNKKKSSP ATKVPSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.045757
Match: 1az9__
Description: Aminopeptidase P; Aminopeptidase P, C-terminal domain

Predicted Domain #3
Region A:
Residues: [469-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDRNSKILRT KLRGEARGGA EDAQKEQIRK ENQKKLHEKL EKNGLLRFSA ADANG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [524-773]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSEPRQYFK KYESYVRDSQ LPTNIRDLRI HVDWKSQTII LPIYGRPVPF HINSYKNGSK  60
   61 NEEGEYTYLR LNFNSPGSSG GISKKVEELP YEESADNQFV RSITLRSKDG DRMSETFKQI 120
  121 ADLKKEATKR EQERKALADV VQQDKLIENK TGRTKRLDQI FVRPNPDTKR VPSTVFIHEN 180
  181 GIRFQSPLRT DSRIDILFSN IKNLIFQSCK GELIVVIHIH LKNPILMGKK KIQDVQFYRE 240
  241 ASDMSVDETG 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [774-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGRRGQSRFR RYGDEDELEQ EQEERRKRAA LDKEFKYFAD AIAEASNGLL TVENTFRDLG  60
   61 FQGVPNRSAV FCMPTTDCLV QLIEPPFLVI NLEEVEICIL ERVQFGLKNF DMVFVYKDFN 120
  121 KPVTHINTVP IESLDFLKQW LTDMD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [919-1035]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPYTVSTINL NWATIMKSLQ DDPYQFFLDG GWNFLATGSD DEASDESEEE VSEYEASEDD  60
   61 VSDESAFSED EEGSEVDDDI SGDESEDYTG DESEEGEDWD ELEKKAARAD RGANFRD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle