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View Structure Prediction Details

Protein: YGL159W
Organism: Saccharomyces cerevisiae
Length: 370 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGL159W.

Description E-value Query
Range
Subject
Range
YGL159W - Putative protein of unknown function; deletion mutant has no detectable phenotype
YGP9_YEAST - Uncharacterized protein YGL159W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGL159W ...
gi|151943654 - gi|151943654|gb|EDN61964.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..370] [1..370]
gi|50513267, gi|... - pir||H69457 ornithine cyclodeaminase (arcB) homolog - Archaeoglobus fulgidus, gi|50513268|pdb|1OMO|B...
ALADH_ARCFU - Alanine dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / N...
2.0E-76 [1..363] [1..309]
gi|7482770 - pir||C69066 ornithine cyclodeaminase - Methanobacterium thermoautotrophicum (strain Delta H)
gi|15679492, gi|... - gi|2622612|gb|AAB85970.1| ornithine cyclodeaminase [Methanothermobacter thermautotrophicus str. Delt...
3.0E-70 [2..370] [12..334]
gi|1066073, gi|1... - gi|1588855|prf||2209368B arginase, gi|1066073|gb|AAC43978.1| ornithine cyclodeaminase
1.0E-69 [14..361] [9..317]
CRYM_MACFL - Ketimine reductase mu-crystallin OS=Macropus fuliginosus GN=CRYM PE=2 SV=1
gi|283930 - gi|283930|pir||S27950 ornithine cyclodeaminase-related protein - eastern gray kangaroo
2.0E-69 [6..360] [8..308]
gi|10955008, gi|... - gi|6498361|dbj|BAA87813.1| tiorf188 [Agrobacterium tumefaciens], gi|10955008|ref|NP_053428.1| ornith...
OCD_AGRFC - Ornithine cyclodeaminase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=arcB PE=3 SV=2
6.0E-69 [14..361] [9..317]
OCD_BRUME - Ornithine cyclodeaminase OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=...
OCD_BRUME - Ornithine cyclodeaminase OS=Brucella melitensis GN=arcB PE=3 SV=1
2.0E-68 [14..370] [9..325]
OCD_BRUAB - Ornithine cyclodeaminase OS=Brucella abortus biovar 1 (strain 9-941) GN=arcB PE=3 SV=1
OCD_BRUAB - Ornithine cyclodeaminase OS=Brucella abortus GN=arcB PE=3 SV=1
4.0E-68 [14..370] [9..325]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSIITDDE VREFYLNCSS QTIIESLLSL HESLRLYSQN HEILLNRMFK KLDETNADSN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.828 a.4.5 "Winged helix" DNA-binding domain
View Download 0.804 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.639 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.607 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.602 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.601 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.562 a.118.11 Cytochrome c oxidase subunit E
View Download 0.544 a.74.1 Cyclin-like
View Download 0.540 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.539 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.537 a.4.5 "Winged helix" DNA-binding domain
View Download 0.529 a.5.6 Hypothetical protein MTH1615
View Download 0.524 a.4.1 Homeodomain-like
View Download 0.502 a.5.2 UBA-like
View Download 0.500 a.4.1 Homeodomain-like
View Download 0.493 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.493 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.479 a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.448 a.17.1 p8-MTCP1
View Download 0.448 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.446 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.425 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.415 a.144.1 PABC (PABP) domain
View Download 0.415 a.126.1 Serum albumin-like
View Download 0.410 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.397 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.390 d.47.1 Ribosomal protein L11, N-terminal domain
View Download 0.389 a.4.1 Homeodomain-like
View Download 0.386 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.377 a.74.1 Cyclin-like
View Download 0.364 a.64.1 Saposin
View Download 0.358 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.353 a.64.2 Bacteriocin AS-48
View Download 0.351 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.343 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.341 a.144.2 Ribosomal protein L20
View Download 0.337 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.334 a.5.2 UBA-like
View Download 0.328 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.323 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.315 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.308 a.39.1 EF-hand
View Download 0.306 a.6.1 Putative DNA-binding domain
View Download 0.304 a.64.1 Saposin
View Download 0.300 a.65.1 Annexin
View Download 0.296 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.295 a.74.1 Cyclin-like
View Download 0.290 a.4.1 Homeodomain-like
View Download 0.286 a.85.1 Hemocyanin, N-terminal domain
View Download 0.286 a.64.1 Saposin
View Download 0.282 a.101.1 Uteroglobin-like
View Download 0.275 a.4.1 Homeodomain-like
View Download 0.273 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.272 a.46.1 Methionine synthase domain
View Download 0.271 a.4.5 "Winged helix" DNA-binding domain
View Download 0.260 a.60.8 HRDC-like
View Download 0.258 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.253 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.251 a.29.4 RecG, N-terminal domain
View Download 0.250 d.50.3 PI-Pfui intein middle domain
View Download 0.248 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.245 d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.235 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.235 a.60.2 RuvA domain 2-like
View Download 0.233 a.3.1 Cytochrome c
View Download 0.231 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.231 a.4.5 "Winged helix" DNA-binding domain
View Download 0.230 a.4.5 "Winged helix" DNA-binding domain
View Download 0.218 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.217 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.209 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.208 a.4.5 "Winged helix" DNA-binding domain
View Download 0.205 a.39.1 EF-hand
View Download 0.205 d.64.1 eIF1-like
View Download 0.205 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted functions:

Term Confidence Notes
catalytic activity 1.03099072397093 bayes_pls_golite062009
oxidoreductase activity 0.442294542097958 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [61-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISHIFMPVVS KDFSGIKILV NNNNKNFQGV INVIEPETGK LIGCFEAKQI TAIRTALASC  60
   61 IGLYKQLSCS HDKLFRFENG TCYLTCFGTG LQAFWHIYIA IKLIMSGIVG ESLKLVEINI 120
  121 LYHNNMMSLD RLKSLKNLFG SNIKIELNQY QINDISSEGN GAVSNSDIIF GCLPTLEPNL 180
  181 FLRQLLNSKA SVEQKHTYIS LIGSYKPVMH ECDKELIDKF KSD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.53
Match: 1gpjA
Description: Glutamyl tRNA-reductase dimerization domain; Glutamyl tRNA-reductase middle domain; Glutamyl tRNA-reductase catalytic, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [284-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NESACILVDS REHTLLESGE LIDSNIAPHN LIEIGELDTL KNTVLNLNEK GCKRTITLCK  60
   61 IVGLAVMDVA LAKEFLSLRT KNTENKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.528 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.334 c.47.1 Thioredoxin-like
View Download 0.333 c.47.1 Thioredoxin-like
View Download 0.299 a.60.2 RuvA domain 2-like
View Download 0.271 d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.244 d.57.1 DNA damage-inducible protein DinI
View Download 0.239 d.129.1 TATA-box binding protein-like
View Download 0.221 d.58.5 GlnB-like
View Download 0.219 c.47.1 Thioredoxin-like
View Download 0.215 a.74.1 Cyclin-like
View Download 0.215 a.60.8 HRDC-like
View Download 0.214 d.94.1 HPr-like
View Download 0.207 b.55.1 PH domain-like
View Download 0.201 d.58.14 Ribosomal protein S6
View Download 0.201 d.120.1 Cytochrome b5


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle