YRC Public Data Repository - Protein Structure Prediction

Protein:	LYS5
Organism:	Saccharomyces cerevisiae
Length:	272 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LYS5.

Description	E-value	Query Range	Subject Range
LYS5_YEAST - L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Saccharomyces cerevisia... LYS5 - Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p...	7.0E-91	[1..272]	[1..272]
ADPPT_MOUSE - L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Mus musculus GN=Aasdhpp...	3.0E-64	[1..219]	[1..221]
gi\|9295190 - gi\|9295190\|gb\|AAF86879.1\|AF201943_1 HAH-P [Homo sapiens]	3.0E-61	[1..219]	[25..245]
CE06529 - B.subtilis SFP protein like status:Partially_confirmed UniProt:Q22856 protein_id:CAA99933.1	1.0E-53	[24..233]	[5..223]
gi\|20147157, gi\|... - gi\|22330990\|ref\|NP_187754.2\| 4'-phosphopantetheinyl transferase family protein [Arabidopsis thaliana...	9.0E-50	[4..201]	[14..217]
SFP_BACSU - 4'-phosphopantetheinyl transferase sfp OS=Bacillus subtilis (strain 168) GN=sfp PE=1 SV=2 SFP_BACSU - 4'-phosphopantetheinyl transferase sfp OS=Bacillus subtilis GN=sfp PE=1 SV=2	2.0E-49	[31..220]	[9..194]

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Predicted Domain #1

Region A:
Residues: [1-113]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKTTEVVSE VSKVAGVRPW AGIFVVEIQE DILADEFTFE ALMRTLPLAS QARILNKKSF  60
   61 HDRCSNLCSQ LLQLFGCSIV TGLNFQELKF DKGSFGKPFL DNNRFLPFSM TIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.522879
Match:	1qr0A_
Description:	4'-Phosphopantetheinyl transferase SFP
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [114-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQYVAMFLVK CVSTDEYQDV GIDIASPCNY GGREELELFK EVFSEREFNG LLKASDPCTI  60
   61 FTYLWSLKES YTKFTGTGLN TDLSLIDFGA ISFFPAEGAS MCITLDEVPL IFHSQWFNNE 120
  121 IVTICMPKSI SDKINTNRPK LYNISLSTLI DYFIENDGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.522879
Match:	1qr0A_
Description:	4'-Phosphopantetheinyl transferase SFP
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits