| Protein: | HUL5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 910 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HUL5.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..910] | [1..910] |
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0.0 | [288..910] | [476..1066] |
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0.0 | [235..909] | [214..871] |
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0.0 | [235..909] | [228..884] |
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Region A: Residues: [1-323] |
1 11 21 31 41 51
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1 MLNFTGQTRR RNVNLGNRTR NSKKDLLEKA KRERERRAQD KLKEDASKTI QKSIRRHFSN 60
61 VRLFKNTFTS SQLVHMIPAY GGKLIYYISQ YDLQQLLKLS HNFLSSYPNS LGNRQLLSLL 120
121 KLYQDDALVA ETLSDLNMDC PTVDEFLDSL SVYLCRASFL SYSSASKLAD VIEAWEVMHS 180
181 SASISIFSIS IGSYEKRPFA LQFYCILAER NLLPQLINTN PILWDNMAKT YSHCSKGGQK 240
241 NIAKLLIPNF NNHIAPSVLR SDNDYVLKFY EKAFIDEVIA TTANYVSDED HVKNLMCYIA 300
301 SSPNQSCKNS VLITLLSNKD FVR
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [324-458] |
1 11 21 31 41 51
| | | | | |
1 RLSWEFFHTK FNASKTEAHP LFSVLAQLID MHLLISTDRE LLDYNSVIPI EELKKFTSTL 60
61 KDFTFRQYWE LPKSERNPML KEAVPLLSKV YERDSRLHFL STENNPTYWE NSEKQFLNLR 120
121 FYEELQEYED LYREH
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.569 | 0.259 | protein polyubiquitination | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.635 | 0.035 | protein polyubiquitination | a.47.2 | t-snare proteins |
| View | Download | 0.574 | 0.026 | protein polyubiquitination | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.872 | 0.024 | protein polyubiquitination | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.565 | 0.005 | protein polyubiquitination | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.554 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.552 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.548 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.524 | N/A | N/A | a.47.1 | STAT |
| View | Download | 0.521 | N/A | N/A | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.421 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.387 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.340 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.338 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.334 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.302 | N/A | N/A | a.19.1 | Fertilization protein |
| View | Download | 0.292 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.285 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.284 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.283 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.282 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.281 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.279 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.276 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.276 | N/A | N/A | a.182.1 | GatB/YqeY domain |
| View | Download | 0.261 | N/A | N/A | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.260 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.258 | N/A | N/A | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.258 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.252 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.251 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.246 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.245 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.240 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.236 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.236 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.235 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.214 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.213 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.212 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.209 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.203 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.201 | N/A | N/A | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.200 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
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Region A: Residues: [459-549] |
1 11 21 31 41 51
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1 LEEESDEDME KEIDLDKERP PLKSLLLNKM KKRLKSSLRF RKLEILLELP FFIPFEERVD 60
61 LFYMFIALDK KRLSLDDDHN LINMFTPWAS T
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.502 | a.39.1 | EF-hand |
| View | Download | 0.455 | a.77.1 | DEATH domain |
| View | Download | 0.492 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.534 | d.58.49 | YajQ-like |
| View | Download | 0.441 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.382 | a.39.1 | EF-hand |
| View | Download | 0.358 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.347 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.342 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.330 | a.74.1 | Cyclin-like |
| View | Download | 0.311 | a.39.1 | EF-hand |
| View | Download | 0.305 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.303 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.287 | a.74.1 | Cyclin-like |
| View | Download | 0.278 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.277 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.275 | d.15.6 | Superantigen toxins, C-terminal domain |
| View | Download | 0.267 | b.34.9 | Tudor/PWWP/MBT |
| View | Download | 0.261 | a.39.1 | EF-hand |
| View | Download | 0.254 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.250 | b.34.1 | C-terminal domain of transcriptional repressors |
| View | Download | 0.247 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.246 | a.118.1 | ARM repeat |
| View | Download | 0.239 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.237 | a.118.1 | ARM repeat |
| View | Download | 0.235 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.234 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.220 | d.129.4 | Cell-division protein ZipA, C-terminal domain |
| View | Download | 0.220 | a.23.2 | Diol dehydratase, gamma subunit |
| View | Download | 0.218 | a.74.1 | Cyclin-like |
| View | Download | 0.214 | d.189.1 | PX domain |
| View | Download | 0.204 | d.58.48 | MTH1187-like |
| View | Download | 0.202 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
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Region A: Residues: [550-596] |
1 11 21 31 41 51
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1 GMRKQSAIIS RDNVLEDAFN AFNSIGERFK ASLDVTFINE FGEEAGI
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| Detection Method: | |
| Confidence: | 504.228787 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [597-695] |
1 11 21 31 41 51
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1 DGGGITKEFL TTVSDEGFKD PKHELFRTND RYELYPSVVY DATKLKYIWF LGKVVGKCLY 60
61 EHVLIDVSFA DFFLKKLLNY SNGFLSSFSD LGSYDSVLY
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Region B: Residues: [752-794] |
1 11 21 31 41 51
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1 TDYKLNKRCF KPVSAFHGGL SVIIAPHWME MFNSIELQML ISG
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| Detection Method: | |
| Confidence: | 504.228787 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [696-751] |
1 11 21 31 41 51
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1 NNLIKLLNMT TDEIKSLDLT FEIDEPESSA KVVDLIPNGS KTYVTKDNVL LYVTKV
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Region B: Residues: [795-910] |
1 11 21 31 41 51
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1 ERDNIDLDDL KSNTEYGGYK EEDQTIVDFW EVLNEFKFEE KLNFLKFVTS VPQAPLQGFK 60
61 ALDPKFGIRN AGTEKYRLPT ASTCVNLLKL PDYRNKTILR EKLLYAINSG ARFDLS
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| Detection Method: | |
| Confidence: | 504.228787 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
| Matching Structure (courtesy of the PDB): |
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