YRC Public Data Repository - Protein Structure Prediction

Protein:	YGL140C
Organism:	Saccharomyces cerevisiae
Length:	1219 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGL140C.

Description	E-value	Query Range	Subject Range
YGO0_YEAST - Uncharacterized membrane protein YGL140C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... YGL140C - Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane ...	0.0	[1..1219]	[1..1219]
YDG8_SCHPO - Uncharacterized protein C26F1.08c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC26F1... SPAC26F1.08c - conserved protein	2.0E-69	[581..944]	[533..887]
ALMT3_ARATH - Putative aluminum-activated malate transporter 3 OS=Arabidopsis thaliana GN=ALMT3 PE=3 SV=1	4.0E-68	[573..954]	[39..429]
gi\|11347658 - pir\|\|D83588 conserved hypothetical protein PA0454 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|15595651, gi\|... - gi\|9946314\|gb\|AAG03843.1\|AE004483_1 conserved hypothetical protein [Pseudomonas aeruginosa PAO1], gi... gi\|218769417, gi... - gi\|218889194\|ref\|YP_002438058.1\| hypothetical protein PLES_04501 [Pseudomonas aeruginosa LESB58], gi...	2.0E-66	[539..948]	[302..723]
gi\|15830298, gi\|... - gi\|15830298\|ref\|NP_309071.1\| hypothetical protein ECs1044 [Escherichia coli O157:H7], gi\|13360504\|db... gi\|208725739, gi... - gi\|208805938\|ref\|ZP_03248275.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4206], gi... gi\|195935147 - gi\|195935147\|ref\|ZP_03080529.1\| hypothetical protein EscherichcoliO157_01607 [Escherichia coli O157:... gi\|189376548, gi... - gi\|189376548\|gb\|EDU94964.1\| putative membrane protein [Escherichia coli O157:H7 str. EC508], gi\|1688... gi\|189372609, gi... - gi\|189372609\|gb\|EDU91025.1\| putative membrane protein [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|217320807, gi... - gi\|217324586\|ref\|ZP_03440670.1\| putative membrane protein [Escherichia coli O157:H7 str. TW14588], g... gi\|25304429, gi\|... - pir\|\|D90759 hypothetical protein ECs1044 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|209160190, gi... - gi\|209398790\|ref\|YP_002269628.1\| hypothetical protein ECH74115_1123 [Escherichia coli O157:H7 str. E... gi\|15830298, gi\|... - gi\|15830298\|ref\|NP_309071.1\| hypothetical protein ECs1044 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|208737604, gi... - gi\|208822119\|ref\|ZP_03262438.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4042], gi... gi\|208814892, gi... - gi\|208814892\|ref\|ZP_03256071.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4045], gi... gi\|168758916, gi... - gi\|189354353\|gb\|EDU72772.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|74311517, gi\|... - gi\|74311517\|ref\|YP_309936.1\| hypothetical protein SSON_0964 [Shigella sonnei Ss046], gi\|73854994\|gb\|... gi\|189001334, gi... - gi\|189001334\|gb\|EDU70320.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4076], gi\|168... gi\|168777451, gi... - gi\|187767322\|gb\|EDU31166.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189359576, gi... - gi\|189359576\|gb\|EDU77995.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|189364955, gi... - gi\|189364955\|gb\|EDU83371.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4501], gi\|168...	8.0E-66	[559..939]	[340..717]
gi\|124529101, gi... - gi\|124529101\|ref\|ZP_01700211.1\| hypothetical membrane protein [Escherichia coli B], gi\|124500056\|gb\|... gi\|253774010, gi... - gi\|253774010\|ref\|YP_003036841.1\| hypothetical protein ECBD_2634 [Escherichia coli BL21(DE3)], gi\|253... gi\|4062528, gi\|1... - dbj\|BAA35725.1\| Hypothetical protein HI1680 [Escherichia coli K12], gb\|AAC74046.1\| orf, hypothetica... gi\|188492374, gi... - gi\|75513413\|ref\|ZP_00735817.1\| COG1289: Predicted membrane protein [Escherichia coli 53638], gi\|1884... gi\|7429612, gi\|4... - gi\|7429612\|pir\|\|G64836 probable membrane protein yccS - Escherichia coli (strain K-12), dbj\|BAA35718... gi\|157066161, gi... - gi\|75195149\|ref\|ZP_00705219.1\| COG1289: Predicted membrane protein [Escherichia coli HS], gi\|1571604... gi\|170020639, gi... - gi\|170020639\|ref\|YP_001725593.1\| hypothetical protein EcolC_2636 [Escherichia coli ATCC 8739], gi\|16...	8.0E-66	[559..939]	[340..717]
gi\|169888453, gi... - gi\|170080618\|ref\|YP_001729938.1\| inner membrane protein [Escherichia coli str. K-12 substr. DH10B], ... gi\|251784502, gi... - gi\|251784502\|ref\|YP_002998806.1\| hypothetical protein B21_00971 [Escherichia coli BL21], gi\|24237677... gi\|254161074, gi... - gi\|254161074\|ref\|YP_003044182.1\| predicted inner membrane protein [Escherichia coli B str. REL606], ... gi\|238900218, gi... - gi\|238900218\|ref\|YP_002926014.1\| putative inner membrane protein [Escherichia coli BW2952], gi\|23886... YCCS_ECOLI - Inner membrane protein yccS - Escherichia coli gi\|254287882, gi... - gi\|254287882\|ref\|YP_003053630.1\| predicted inner membrane protein [Escherichia coli BL21(DE3)], gi\|2... gi\|89107810, gi\|... - gi\|89107810\|ref\|AP_001590.1\| predicted inner membrane protein [Escherichia coli str. K-12 substr. W3... EG13721 - putative transporter, FUSC superfamily inner membrane protein / Putative transporter, FUSC superfami... EG13721 - putative transporter, FUSC superfamily inner membrane protein / Putative transporter, FUSC superfami...	8.0E-66	[559..939]	[337..714]
gi\|12514145, gi\|... - gi\|15800819\|ref\|NP_286835.1\| hypothetical protein Z1311 [Escherichia coli O157:H7 EDL933], gi\|125141... gi\|25304436 - pir\|\|B85623 hypothetical protein Z1311 [imported] - Escherichia coli (strain O157:H7, substrain EDL...	9.0E-65	[559..939]	[340..717]
gi\|16502248, gi\|... - gi\|25304439\|pir\|\|AD0627 probable membrane protein STY1095 [imported] - Salmonella enterica subsp. en... gi\|29137904, gi\|... - gi\|29142274\|ref\|NP_805616.1\| hypothetical protein t1847 [Salmonella enterica subsp. enterica serovar... gi\|213851963 - gi\|213851963\|ref\|ZP_03381495.1\| hypothetical protein SentesT_03192 [Salmonella enterica subsp. enter... gi\|214001666 - gi\|214001666\|ref\|ZP_03412401.1\| hypothetical protein Salmonellentericaenterica_14899 [Salmonella ent... gi\|16759954 - gi\|16759954\|ref\|NP_455571.1\| hypothetical protein STY1095 [Salmonella enterica subsp. enterica serov...	8.0E-60	[559..916]	[337..674]
gi\|16764432, gi\|... - gi\|16764432\|ref\|NP_460047.1\| putative transporter [Salmonella typhimurium LT2], gi\|16419588\|gb\|AAL20... gi\|194407595, gi... - gi\|194449291\|ref\|YP_002045075.1\| hypothetical membrane protein [Salmonella enterica subsp. enterica ... gi\|205337173, gi... - gi\|205337173\|gb\|EDZ23937.1\| hypothetical membrane protein [Salmonella enterica subsp. enterica serov... gi\|168264166, gi... - gi\|205347325\|gb\|EDZ33956.1\| hypothetical membrane protein [Salmonella enterica subsp. enterica serov... gi\|167994901, gi... - gi\|205327292\|gb\|EDZ14056.1\| hypothetical membrane protein [Salmonella enterica subsp. enterica serov... lcl\|NC_016856.1_... - [gene=yccS] [protein=putative transporter] [protein_id=YP_005236807.1] [location=complement(1122036....	1.0E-59	[559..916]	[337..674]

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Predicted Domain #1

Region A:
Residues: [1-576]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKSKLTKI QKLWLYYFPC DRILAKRICK STVNTTVAFI FCLIPKITAH LGAAPAMLPM  60
   61 ISVIVHPGRR VGGTIHGAIY CITGLIFGLA YAIFGRFLAQ RCLGSSWHEL TEAQQHVLHY 120
  121 KRYEAGLAIL AVFEVIMLFF HGWMRSVSHY YFGIVFPLFV VVHFAFMDPL NETAGTIAKA 180
  181 YSTPFYLGIA MSIFWNLVLF PEWGTTYLGN TTIDAMNELH KSIDYSINFF IAVDPHNSSQ 240
  241 LYSRDPVSLG KLLKMKSLIS SKVNNCRVVL HECIYEFTYA YVSPTKLKPI ISTLENLTVF 300
  301 INGLVNTCQL EFILLARHDN KLRPDDVAAL TLPKNKEISF ANAEKLLKVI DKLHPVIYSL 360
  361 HRTMSECMYI AKLVLAHAFD VKVSRVHSCS MFKDGNFPTF SNNANNLPND VDIQNKINDL 420
  421 KQALEECKAK FKSEMLSFDI DIMSPSDEMF LLSSFLLNFR QTADSTLVIM ESVKDILVKR 480
  481 QIQEKKGWLR GKRLWFLVLT NYETFSIWLK GDRNSVTEND TLKGTFNGNT NGFAHDTVIR 540
  541 RPDYEENELL SQKVSSNKNI VKDDASLDLP MTSEPK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [577-931]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNSSSTSDTS SSPLTLTKTT TFGTNRTSRR QGRFSFMSML ISIDKFCEVS HPHFRFGFQV  60
   61 AIALMLASFP MFIPKTRQWY IDYRGTWIGF VCILCLEPSV GGTFWVFFLR AVGVIFGAAW 120
  121 GYLSYVAAVN QTNPYLETVI TVFGAIPGFY YLLGTPYVKA AIIEIISIYI VMLAAILPSQ 180
  181 DDILTSFAKR CLAVGYGGGV ALIVQVFFFP LKAREQLNEE ISFVCGCISE MELLYATGLE 240
  241 GEQVASSMSE EKYKKIEKIS KSAKEALARA TAYKGLTRQE PRLKGEYTEL ENVFTQVIFI 300
  301 QKQIIERIDT ISLLRKQNGS AVIEEFNSVV YPYRRQMVGS ISCLMRALQE AFINK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [932-1219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPLPQFLPSA RIAHRRLINK VRQTLRIRYP GQISNLSDKA RKPNEGDYAD GKDEDDDDNE  60
   61 GLVMKMNRRG QANTTANPHE YVLKEKFLSW NASSAASEEI IEYIEELLNL TKILVGVNEF 120
  121 KYGFLSRPLY EDWAAEAVTG FDNFINGKSN PMNTRRNRTP FDGTSIISEG NESLQSTNSN 180
  181 ESQISPDSTR SYEPECPVAY EKNDNPAALN LLRIASHKAG QNADGLPKTF RNRAFSITST 240
  241 SGQLSSLSRH STLGNADPNY LNDDDESSDD DLPLALKMVL SHMKEKKD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [608-757]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRFSFMSMLI SIDKFCEVSH PHFRFGFQVA IALMLASFPM FIPKTRQWYI DYRGTWIGFV  60
   61 CILCLEPSVG GTFWVFFLRA VGVIFGAAWG YLSYVAAVNQ TNPYLETVIT VFGAIPGFYY 120
  121 LLGTPYVKAA IIEIISIYIV MLAAILPSQD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [758-1219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DILTSFAKRC LAVGYGGGVA LIVQVFFFPL KAREQLNEEI SFVCGCISEM ELLYATGLEG  60
   61 EQVASSMSEE KYKKIEKISK SAKEALARAT AYKGLTRQEP RLKGEYTELE NVFTQVIFIQ 120
  121 KQIIERIDTI SLLRKQNGSA VIEEFNSVVY PYRRQMVGSI SCLMRALQEA FINKTPLPQF 180
  181 LPSARIAHRR LINKVRQTLR IRYPGQISNL SDKARKPNEG DYADGKDEDD DDNEGLVMKM 240
  241 NRRGQANTTA NPHEYVLKEK FLSWNASSAA SEEIIEYIEE LLNLTKILVG VNEFKYGFLS 300
  301 RPLYEDWAAE AVTGFDNFIN GKSNPMNTRR NRTPFDGTSI ISEGNESLQS TNSNESQISP 360
  361 DSTRSYEPEC PVAYEKNDNP AALNLLRIAS HKAGQNADGL PKTFRNRAFS ITSTSGQLSS 420
  421 LSRHSTLGNA DPNYLNDDDE SSDDDLPLAL KMVLSHMKEK KD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.12
Match:	2oevA
Description:	No description for 2oevA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits