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View Structure Prediction Details

Protein: SNT2
Organism: Saccharomyces cerevisiae
Length: 1403 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNT2.

Description E-value Query
Range
Subject
Range
gi|1945299 - gi|1945299|emb|CAA96841.1| unnamed protein product [Saccharomyces cerevisiae]
0.0 [1..1388] [1..1388]
AIRE_MOUSE - Autoimmune regulator OS=Mus musculus GN=Aire PE=1 SV=1
3.0E-59 [766..1205] [58..459]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-55 [817..1262] [33..461]
gi|119584380, gi... - gi|19584408|emb|CAD28495.1| hypothetical protein [Homo sapiens], gi|119584380|gb|EAW63976.1| bromodo...
4.0E-55 [817..1262] [33..461]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKEEDFQLP RRREAAKNVN YNEMEIDTKL VQQIQIAEKS GAKTKGSNSQ TPRNCKRTSN  60
   61 PASRNEKFKY QKFLHDKNTC WNFIPTLPPS FRKNSRFSNI LD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.203 a.74.1 Cyclin-like
View Download 0.202 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.257 a.55.1 IHF-like DNA-binding proteins
View Download 0.260 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.260 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.257 a.55.1 IHF-like DNA-binding proteins
View Download 0.203 a.74.1 Cyclin-like
View Download 0.202 a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #2
Region A:
Residues: [103-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDDAMIDLKK MSLFNTESVL LSANDTIYMI SEPAGEPYYV GRVVNFVSKP EFSNTIHEAI  60
   61 KTTSVFPAKF FQVRMNWFYR PRDIQEHVNT FNPRLVYASL HQDICPISSY RGKCSIFHKD 120
  121 EVFDVLPNEK ECIIRPNIFY FDELFDRYTL KYYKVYSTDK ILNKWNSKSP 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 31.420216
Match: PF01426
Description: BAH domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLYVLNRRFR YIYTEPKYPL ENVLKKYVFH ELEVNELSPA DYQWDKRCQF CKEWCIQKES  60
   61 LSCDECGVCA HLYCMDPPLD RKPNKDVVWT CFSCLQKQQG TKDSHVRFLE EQALELDFIR 120
  121 SVRQKIEEIS SKAIKENVGY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1fp0A_
Description: Nuclear corepressor KAP-1 (TIF-1beta)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [413-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTENCWFQYL GIYSISHIGD ALNDSMFFPY PFKPSRVGVK YQWNGCNHNV PWRRNSYISA  60
   61 NSEEERGS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.340 0.598 nucleus a.21.1 HMG-box
View Download 0.435 0.077 cytoplasm a.16.1 S15/NS1 RNA-binding domain
View Download 0.335 0.059 cytoplasm d.58.17 Metal-binding domain
View Download 0.280 0.000 nucleus f.13.1 Family A G protein-coupled receptor-like
View Download 0.309 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.278 N/A N/A c.15.1 BRCT domain
View Download 0.278 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.267 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.261 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.241 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.215 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.204 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.204 N/A N/A a.7.7 BAG domain

Predicted Domain #5
Region A:
Residues: [481-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKTSELAWVL DASKITTRKL SEYIEQCKSE ICPILNVRGE TCNFIDVVLK NLLFTNYDTA  60
   61 EAFKKCKREL SRKFLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.632 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.608 a.64.1 Saposin
View Download 0.613 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.615 d.68.4 YhbY-like
View Download 0.575 a.64.1 Saposin
View Download 0.555 a.1.1 Globin-like
View Download 0.548 a.60.11 Hypothetical protein YjbJ
View Download 0.513 a.74.1 Cyclin-like
View Download 0.507 a.5.6 Hypothetical protein MTH1615
View Download 0.492 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.476 b.84.2 Rudiment single hybrid motif
View Download 0.476 a.77.1 DEATH domain
View Download 0.468 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.465 a.133.1 Phospholipase A2, PLA2
View Download 0.446 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.444 a.118.8 TPR-like
View Download 0.429 a.112.1 Description not found.
View Download 0.424 a.74.1 Cyclin-like
View Download 0.411 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.404 a.60.2 RuvA domain 2-like
View Download 0.364 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.363 d.50.3 PI-Pfui intein middle domain
View Download 0.361 a.29.4 RecG, N-terminal domain
View Download 0.344 a.77.1 DEATH domain
View Download 0.335 a.24.3 Cytochromes
View Download 0.335 a.4.5 "Winged helix" DNA-binding domain
View Download 0.331 a.1.1 Globin-like
View Download 0.328 a.118.11 Cytochrome c oxidase subunit E
View Download 0.318 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.317 a.126.1 Serum albumin-like
View Download 0.296 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.293 a.144.1 PABC (PABP) domain
View Download 0.289 d.45.1 ClpS-like
View Download 0.280 a.3.1 Cytochrome c
View Download 0.276 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.271 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.269 a.61.1 Retroviral matrix proteins
View Download 0.269 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.265 a.4.5 "Winged helix" DNA-binding domain
View Download 0.264 a.130.1 Chorismate mutase II
View Download 0.261 a.74.1 Cyclin-like
View Download 0.260 a.4.8 Ribosomal protein S18
View Download 0.256 a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.251 d.58.14 Ribosomal protein S6
View Download 0.248 a.36.1 Signal peptide-binding domain
View Download 0.247 a.16.1 S15/NS1 RNA-binding domain
View Download 0.244 e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.242 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.241 a.64.1 Saposin
View Download 0.240 a.46.1 Methionine synthase domain
View Download 0.238 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.238 a.4.5 "Winged helix" DNA-binding domain
View Download 0.238 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.231 a.39.1 EF-hand
View Download 0.226 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.224 a.4.5 "Winged helix" DNA-binding domain
View Download 0.223 d.68.7 R3H domain
View Download 0.221 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.220 d.68.3 SirA-like
View Download 0.219 a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 a.5.2 UBA-like
View Download 0.217 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.210 a.24.17 Group V grass pollen allergen
View Download 0.210 a.144.2 Ribosomal protein L20
View Download 0.209 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.207 a.6.1 Putative DNA-binding domain
View Download 0.206 a.39.4 Hypothetical protein MTH865
View Download 0.203 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.202 a.39.1 EF-hand
View Download 0.201 a.81.1 N-terminal domain of DnaB helicase

Predicted Domain #6
Region A:
Residues: [557-628]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPSFTAVEIR KFEEAVEKFG SELRPVCEYV GTQPMSMIVR FYYNWKKTER GLTVRGKLSK  60
   61 LSKNKRKKEI AN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 10.376751
Match: PF00249
Description: Myb-like DNA-binding domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [629-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HENDVETKYI DDSSFDTEKL SLAESSFQCM FCKTDYSPMW YRVTGGSDDE KIKIRMQTGV  60
   61 NEKTEISEKS PAHSKKNEKL GALCIRCARM WRRYAIKWVP PLETLRKITG TCQNSFYSAI 120
  121 EGIIEENN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.555 a.1.1 Globin-like
View Download 0.513 a.74.1 Cyclin-like
View Download 0.492 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.465 a.133.1 Phospholipase A2, PLA2
View Download 0.446 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.426 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.405 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.404 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.392 f.18.1 F1F0 ATP synthase subunit A
View Download 0.367 a.4.5 "Winged helix" DNA-binding domain
View Download 0.362 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.333 a.7.8 GAT domain
View Download 0.326 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.321 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.314 d.42.1 POZ domain
View Download 0.303 a.25.1 Ferritin-like
View Download 0.298 a.118.1 ARM repeat
View Download 0.289 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.286 a.118.11 Cytochrome c oxidase subunit E
View Download 0.261 a.75.1 Ribosomal protein S7
View Download 0.260 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.258 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.257 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.232 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.224 c.50.1 Macro domain-like
View Download 0.222 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.221 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.218 a.1.1 Globin-like
View Download 0.217 a.1.1 Globin-like
View Download 0.205 d.6.1 Prion-like
View Download 0.204 a.7.1 Spectrin repeat

Predicted Domain #8
Region A:
Residues: [757-1036]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNKFTLSPFQ AHNKLLEWEL VQDSELIIRQ RMKVYKNPNS FVKMKRYSMT FHTQLYKMAV  60
   61 RSYRKNEFHP ETMQRDLELF IEDNKEVRKA IPEQKPERAK NTKDEFPVNI IRQSPGTIKT 120
  121 SDTSRNRKCN DVFIEKASNN NIPKITNASN DLIEISIKTG GSSSGSVSVD KGFKFVKFDN 180
  181 KTFQRLRNSL KLVNNKLPKY NEPSTKKIKM INDIALSNPL NEPNGASYNY TVISHSKETS 240
  241 VALEKYHDGN KPSKMLEKDM ILKHTKNKPK NPDTAWANNS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.254 N/A N/A a.77.1 DEATH domain
View Download 0.219 N/A N/A i.1.1 Ribosome and ribosomal fragments

Predicted Domain #9
Region A:
Residues: [1037-1119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARTFCSVCKE KFNDNDNYEV VCGNCGLTVH YFCYAIKLPK DMKKNTNLKT FKWLCDPCSN  60
   61 DLNPIISTTY QCSMCPTKDY DYD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.853872
Match: PF00628
Description: PHD-finger

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1120-1309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYRSQSFKIC PDALKCTSLG TWVHLVCSLF NEDIKYGNGQ SMQPALNTTA VLIKHSRFTC  60
   61 GVCRINGGGL VKCNKCQYRY HITCAQNSSN FKLMFEKKNM SVDTTLPCIK DVKLNDTYTL 120
  121 RPILICDRHD ISLEGNELYP LSYKPQHTLS YIEQYCRYYK CESDHSLVEL RYFEQLRLRH 180
  181 GEMPGNSHDS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1310-1403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIKPKIYVLP FERTCPHCGT NKSLYWYEDI ICHSCNLRSG AQELDFDSAS ANISNDNGLP  60
   61 VEITQQLMEG IEPAMFDIDI SEAGTDKNTH PSSQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 3.60206
Match: PF00320
Description: GATA zinc finger

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle