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View Structure Prediction Details

Protein: MET13
Organism: Saccharomyces cerevisiae
Length: 599 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MET13.

Description E-value Query
Range
Subject
Range
gi|1628449 - gi|1628449|emb|CAA63833.1| G2882 [Saccharomyces cerevisiae]
0.0 [1..599] [1..599]
MTHR1_ARATH - Methylenetetrahydrofolate reductase 1 OS=Arabidopsis thaliana GN=MTHFR1 PE=1 SV=1
0.0 [1..589] [1..586]
MTHR1_MAIZE - Methylenetetrahydrofolate reductase 1 OS=Zea mays PE=2 SV=1
0.0 [1..589] [1..586]
gi|4753778 - gi|4753778|emb|CAB41971.1| methylenetetrahydrofolate reductase [Homo sapiens]
0.0 [2..585] [67..649]
MTHR1_SCHPO - Methylenetetrahydrofolate reductase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=met9...
met9 - methylenetetrahydrofolate reductase Met9
0.0 [1..588] [1..577]

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Predicted Domain #1
Region A:
Residues: [1-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKITEKLEQH RQTSGKPTYS FEYFVPKTTQ GVQNLYDRMD RMYEASLPQF IDITWNAGGG  60
   61 RLSHLSTDLV ATAQSVLGLE TCMHLTCTNM PISMIDDALE NAYHSGCQNI LALRGDPPRD 120
  121 AENWTPVEGG FQYAKDLIKY IKSKYGDHFA IGVAGYPECH PELPNKDVKL DLEYLSRRST 180
  181 GGDFIITQMF YDVDNLLNWC SQVRAAGMDV PIIPGIMPIT TYAAFLRRIQ WGQISIPQHF 240
  241 SSRLDPIKDD DELVRDIGTN LIVEMCQKLL DSGYVSHLHI YTMNLEKAPL MILERLNILP 300
  301 TESEFNAHPL AVLPWRKSLN PKRKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 419.035458
Match: 1b5tA_
Description: Methylenetetrahydrofolate reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [326-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEVRPIFWKR RPYSYVARTS QWAVDEFPNG RFGDSSSPAF GDLDLCGSDL IRQSANKCLE  60
   61 LWSTPTSIND VAFLVINYLN GNLKCLPWSD IPINDEINPI KAHLIELNQH SIITINSQPQ 120
  121 VNGIRSNDKI HGWGPKDGYV YQKQYLEFML PKTKLPKLID TLKNNEFLTY FAIDSQGDLL 180
  181 SNHPDNSKSN AVTWGIFPGR EILQPTIVEK ISFLAWKEEF YHILNEWKLN MNKYDKPHSA 240
  241 QFIQSLIDDY CLVNIVDNDY ISPDDQIHSI LLSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle