YRC Public Data Repository - Protein Structure Prediction

Protein:	USE1
Organism:	Saccharomyces cerevisiae
Length:	245 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for USE1.

Description	E-value	Query Range	Subject Range
USE1_YEAST - Protein transport protein USE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=USE1 PE=1... USE1 - Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER... gi\|207345374 - gi\|207345374\|gb\|EDZ72216.1\| YGL098Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190407054 - gi\|190407054\|gb\|EDV10321.1\| hypothetical protein SCRG_01096 [Saccharomyces cerevisiae RM11-1a] gi\|151943710 - gi\|151943710\|gb\|EDN62020.1\| Unconventional SNARE in the ER [Saccharomyces cerevisiae YJM789]	0.0	[1..245]	[1..245]
gi\|117646422, gi... - gi\|167773831\|gb\|ABZ92350.1\| uncharacterized hematopoietic stem/progenitor cells protein MDS032 [synt... gi\|55648577 - gi\|55648577\|ref\|XP_512478.1\| PREDICTED: uncharacterized hematopoietic stem/progenitor cells protein ... USE1 - unconventional SNARE in the ER 1 homolog (S. cerevisiae)	2.0E-47	[97..242]	[109..251]
USE1_MOUSE - Vesicle transport protein USE1 OS=Mus musculus GN=Use1 PE=1 SV=1	3.0E-46	[97..242]	[120..262]
USE1_SCHPO - Protein transport protein use1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=use1 PE=3 S... SPAC17G6.07c - SNARE Slt1	9.0E-31	[117..240]	[95..212]
gi\|18410316, gi\|... - gi\|46931290\|gb\|AAT06449.1\| At3g55600 [Arabidopsis thaliana], gi\|18410316\|ref\|NP_567024.1\| unknown pr...	0.001	[32..240]	[36..239]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETSNDPFL SYVLSSKQLT NLNRLRRKAV TKQLGSSDDN KVSEEFLRYQ HTYQREAFEY  60
   61 LQTKHDAHKI MESQYEQYQS SSKTRRYSID LDSVDAVDTE SQTEYPNEEF IDRNEDSEAV 120
  121 MELRKRLLGK GQNKGLGYET TKSVDRQIED QDTLQQDLIQ DMSKLVGSLK QGAVAFQSAL 180
  181 DEDKQVLGAA EIGIQVASQG LMDVSGKLRK YDKSKLSYLF YITVFIFMIL GLVFTFIIIQ 240
  241 LFPAL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pcons
Confidence:	2.18
Match:	1jchA
Description:	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits