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View Structure Prediction Details

Protein: NUP145
Organism: Saccharomyces cerevisiae
Length: 1317 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP145.

Description E-value Query
Range
Subject
Range
gi|496731 - gi|496731|emb|CAA83584.1| nucleoporin [Saccharomyces cerevisiae]
0.0 [1..1309] [1..1309]
nup189 - nucleoporin Nup189
NU189_SCHPO - Nucleoporin nup189 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup189 PE=1 SV=1
0.0 [601..1239] [1047..1711]
gi|15277703, gi|... - gi|30583537|gb|AAP36013.1| nucleoporin 98kDa [Homo sapiens], gi|15277703|gb|AAH12906.1| NUP98 protei...
0.0 [796..1237] [8..497]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [804..1237] [1..482]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNKSVNSGF TFGNQNTSTP TSTPAQPSSS LQFPQKSTGL FGNVNVNANT STPSPSGGLF  60
   61 NANSNANSIS QQPANNSLFG NKPAQPSGGL FGATNNTTSK SAGSLFGNNN ATANSTGSTG 120
  121 LFSGSNNIAS STQNGGLFGN SNNNNITSTT QNGGLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [157-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKPTTTPAGA GGLFGNSSST NSTTGLFGSN NTQSSTGIFG QKPGASTTGG LFGNNGASFP  60
   61 RSGETTGTMS TNPYGINISN VPMAVADMPR SITSSLSDVN GKSDAEPKPI ENRRTYSFSS 120
  121 SVSGNAPLPL ASQSSLVSRL STRLKATQKS TSPNEIFSPS YSKPWLNGAG SAPLVDDFFS 180
  181 SKMTSLAPNE NSIFPQNGFN FLSSQRADLT ELRKLKIDSN RSAAKKLKLL SGTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [391-1049]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AITKKHMQDE QDSSENEPIA NADSVTNIDR KENRDNNLDN TYLNGKEQSN NLNKQDGENT  60
   61 LQHEKSSSFG YWCSPSPEQL ERLSLKQLAA VSNFVIGRRG YGCITFQHDV DLTAFTKSFR 120
  121 EELFGKIVIF RSSKTVEVYP DEATKPMIGH GLNVPAIITL ENVYPVDKKT KKPMKDTTKF 180
  181 AEFQVFDRKL RSMREMNYIS YNPFGGTWTF KVNHFSIWGL VNEEDAEIDE DDLSKQEDGG 240
  241 EQPLRKVRTL AQSKPSDKEV ILKTDGTFGT LSGKDDSIVE EKAYEPDLSD ADFEGIEASP 300
  301 KLDVSKDWVE QLILAGSSLR SVFATSKEFD GPCQNEIDLL FSECNDEIDN AKLIMKERRF 360
  361 TASYTFAKFS TGSMLLTKDI VGKSGVSIKR LPTELQRKFL FDDVYLDKEI EKVTIEARKS 420
  421 NPYPQISESS LLFKDALDYM EKTSSDYNLW KLSSILFDPV SYPYKTDNDQ VKMALLKKER 480
  481 HCRLTSWIVS QIGPEIEEKI RNSSNEIEQI FLYLLLNDVV RASKLAIESK NGHLSVLISY 540
  541 LGSNDPRIRD LAELQLQKWS TGGCSIDKNI SKIYKLLSGS PFEGLFSLKE LESEFSWLCL 600
  601 LNLTLCYGQI DEYSLESLVQ SHLDKFSLPY DDPIGVIFQL YAANENTEKL YKEVRQRTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1050-1234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALDVQFCWYL IQTLRFNGTR VFSKETSDEA TFAFAAQLEF AQLHGHSLFV SCFLNDDKAA  60
   61 EDTIKRLVMR EITLLRASTN DHILNRLKIP SQLIFNAQAL KDRYEGNYLS EVQNLLLGSS 120
  121 YDLAEMAIVT SLGPRLLLSN NPVQNNELKT LREILNEFPD SERDKWSVSI NVFEVYLKLV 180
  181 LDNVE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1235-1317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQETIDSLIS GMKIFYDQYK HCREVAACCN VMSQEIVSKI LEKNNPSIGD SKAKLLELPL  60
   61 GQPEKAYLRG EFAQDLMKCT YKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle