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View Structure Prediction Details

Protein: AFT1
Organism: Saccharomyces cerevisiae
Length: 690 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AFT1.

Description E-value Query
Range
Subject
Range
AFT1 - Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACC...
AFT1_YEAST - Iron-regulated transcriptional activator AFT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
0.0 [1..690] [1..690]

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Predicted Domain #1
Region A:
Residues: [1-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGFNPADIE HASPINSSDS HSSSFVYALP KSASEYVVNH NEGRASASGN PAAVPSPIMT  60
   61 LNLKSTHSLN IDQHVHTSTS PTETIGHIHH VEKLNQNNLI HLDPVPNFED KSDIKPWLQK 120
  121 IFYPQGIELV IERSDAFKVV FKCKAAKRGR NARRKRKDKP KGQDHEDEKS KINDDELEYA 180
  181 SPSNATVTNG PQTSPDQTSS IKPKKKRCVS RFNNCPFRVR ATYSLKRKRW SIVVMDNNHS 240
  241 HQLKFNPDSE EYKKFKEKLR KDNDVDAIKK FDELEYRTLA NLPIPTATIP CDCGLTNEIQ 300
  301 SFNVVLPTNS NVTSSASSST VSSISLDSSN ASKRPCLPSV NNTGSINTNN VRKPKSQCKN 360
  361 KDTLLKRTTM QNFL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [375-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTKSRLRKTG TPTSSQHSST AFSGYIDDPF NLNEILPLPA SDFKLNTVTN LNEIDFTNIF  60
   61 TKSPHPHSGS THPRQVFDQL DDCSSILFSP LTTNTNNEFE GESDDFVHSP YLNSEADFSQ 120
  121 ILSSAPPVHH DPNETHQENQ DIIDRFANSS QEHNEYILQY LTHSDAANHN NIGVPNNNSH 180
  181 SLNTQHNVSD LGNSLLRQEA LVGSSSTKIF DELKFVQNGP HGSQHPIDFQ HVDHRHLSSN 240
  241 EPQVRSHQYG PQQQPPQQLQ YHQNQPHDGH NHEQHQTVQK DMQTHESLEI MGNTLLEEFK 300
  301 DIKMVNGELK YVKPED

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.0
Match: 1qhbA
Description: Haloperoxidase (bromoperoxidase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.732568437339568 bayes_pls_golite062009
hydrolase activity 0.203510976989008 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle