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View Structure Prediction Details

Protein: JAC1
Organism: Saccharomyces cerevisiae
Length: 184 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JAC1.

Description E-value Query
Range		 Subject
Range
gi|16758510, gi|... - gi|16758510|ref|NP_446142.1| DnaJ (Hsp40) homolog, subfamily C, member 14 [Rattus norvegicus], gi|14...
 1.0E-40 [10..183] [439..608]
gi|15029846 - gi|15029846|gb|AAH11146.1| Dnajc14 protein [Mus musculus]
 1.0E-39 [10..183] [441..610]
DJC14_BOVIN - DnaJ homolog subfamily C member 14 OS=Bos taurus GN=DNAJC14 PE=1 SV=1
 2.0E-39 [10..183] [441..606]
DNAJ_THEMA - Chaperone protein DnaJ OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=d...
DNAJ_THEMA - Chaperone protein DnaJ OS=Thermotoga maritima GN=dnaJ PE=3 SV=1
 1.0E-36 [8..163] [2..153]
gi|4680190 - gi|4680190|gb|AAD27555.1|AF111710_1 putative dnaJ-like protein [Oryza sativa subsp. indica]
gi|25458468 - pir||T52064 dnaJ-like protein [imported] - rice
 2.0E-33 [9..184] [281..463]
CG14650-PA - This gene is referred to in FlyBase by the symbol Dmel\CG14650 (CG14650, FBgn0037252). It is a prote...
 8.0E-33 [10..184] [705..878]
DNJ2_AQUAE, DNAJ... - (O66921) Chaperone protein dnaJ-2, Chaperone protein DnaJ 2 OS=Aquifex aeolicus GN=dnaJ2 PE=3 SV=1
DNAJ2_AQUAE - Chaperone protein DnaJ 2 OS=Aquifex aeolicus (strain VF5) GN=dnaJ2 PE=3 SV=1
 2.0E-31 [9..154] [4..145]
JAC1 - Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved...
JAC1_YEAST - J-type co-chaperone JAC1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
 3.0E-31 [1..184] [1..184]

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Predicted Domain #1
Region A:
Residues: [1-71] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKYLVQRRF TSTFYELFPK TFPKKLPIWT IDQSRLRKEY RQLQAQHHPD MAQQGSEQSS  60
   61 TLNQAYHTLK D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.9897
Match: 1fpoA_
Description: HSC20 (HSCB), N-terminal (J) domain; HSC20 (HSCB), C-terminal oligomerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.106988907594358 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [72-184] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLRRSQYMLK LLRNIDLTQE QTSNEVTTSD PQLLLKVLDI HDELSQMDDE AGVKLLEKQN  60
   61 KERIQDIEAQ LGQCYNDKDY AAAVKLTVEL KYWYNLAKAF KDWAPGKQLE MNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.9897
Match: 1fpoA_
Description: HSC20 (HSCB), N-terminal (J) domain; HSC20 (HSCB), C-terminal oligomerisation domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle