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View Structure Prediction Details

Protein: HXK1
Organism: Saccharomyces cerevisiae
Length: 485 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXK1.

Description E-value Query
Range
Subject
Range
gi|171735, gi|224664 - gi|224664|prf||1110197A hexokinase PII, gi|171735|gb|AAA34697.1| hexokinase P-II peptide
0.0 [1..485] [1..486]
HXK_KLULA - Hexokinase OS=Kluyveromyces lactis GN=RAG5 PE=1 SV=3
HXK_KLULA - Hexokinase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-114...
0.0 [1..484] [1..484]
HXK_SCHOC - Hexokinase OS=Schwanniomyces occidentalis GN=HXK PE=3 SV=1
0.0 [1..480] [1..477]
gi|83767060, gi|... - gi|9955857|dbj|BAB12228.1| hexokinase [Aspergillus oryzae], gi|83767060|dbj|BAE57200.1| unnamed prot...
gi|220692437, gi... - gi|238501932|ref|XP_002382200.1| hexokinase Kxk, putative [Aspergillus flavus NRRL3357], gi|22069243...
gi|169769464 - gi|169769464|ref|XP_001819202.1| hypothetical protein [Aspergillus oryzae RIB40]
0.0 [1..482] [1..480]

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Predicted Domain #1
Region A:
Residues: [1-31]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVHLGPKKPQ ARKGSMADVP KELMDEIHQL E

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [311-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELLRLVLLE LNEKGLMLKD QDLSKLKQPY IMDTSYPARI EDDPFENLED TDDIFQKDFG  60
   61 VKTTLPERKL IRRLCE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11000.0
Match: 1ig8A_
Description: Hexokinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [32-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMFTVDSETL RKVVKHFIDE LNKGLTKKGG NIPMIPGWVM EFPTGKESGN YLAIDLGGTN  60
   61 LRVVLVKLSG NHTFDTTQSK YKLPHDMRTT KHQEELWSFI ADSLKDFMVE QELLNTKDTL 120
  121 PLGFTFSYPA SQNKINEGIL QRWTKGFDIP NVEGHDVVPL LQNEISKREL PIEIVALIND 180
  181 TVGTLIASYY TDPETKMGVI FGTGVNGAFY DVVSDIEKLE GKLADDIPSN SPMAINCEYG 240
  241 SFDNEHLVLP RTKYDVAVDE QSPRPGQQAF EKMTSGYYL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [387-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIGTRAARLA VCGIAAICQK RGYKTGHIAA DGSVYNKYPG FKEAAAKGLR DIYGWTGDAS  60
   61 KDPITIVPAE DGSGAGAAVI AALSEKRIAE GKSLGIIGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11000.0
Match: 1ig8A_
Description: Hexokinase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle