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View Structure Prediction Details

Protein: YFR016C
Organism: Saccharomyces cerevisiae
Length: 1233 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFR016C.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
9.0E-83 [75..1149] [839..1890]
MYH11_CHICK - Myosin-11 OS=Gallus gallus GN=MYH11 PE=1 SV=4
1.0E-82 [41..1155] [807..1939]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-82 [41..1155] [807..1939]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
5.0E-82 [75..1149] [837..1888]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
2.0E-81 [75..1149] [842..1893]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVESLTVENQ EHNVQPPSVT SAGDSYSTLA TDLPLPSTND IIESRDQLTE SDLDEAINAT  60
   61 ENFAQELSSQ RKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.424 d.58.1 4Fe-4S ferredoxins
View Download 0.389 a.36.1 Signal peptide-binding domain
View Download 0.348 a.2.7 tRNA-binding arm
View Download 0.416 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.333 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.326 d.56.1 GroEL-intermediate domain like
View Download 0.315 a.29.4 RecG, N-terminal domain
View Download 0.306 a.60.1 SAM/Pointed domain
View Download 0.299 a.83.1 Guanido kinase N-terminal domain
View Download 0.290 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.289 a.156.1 S13-like H2TH domain
View Download 0.267 f.17.1 F1F0 ATP synthase subunit C
View Download 0.266 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.253 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.248 a.46.1 Methionine synthase domain
View Download 0.244 a.7.6 Ribosomal protein S20
View Download 0.244 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.237 a.144.1 PABC (PABP) domain
View Download 0.237 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.228 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.215 a.24.17 Group V grass pollen allergen
View Download 0.212 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.211 a.77.1 DEATH domain
View Download 0.202 a.39.1 EF-hand

Predicted Domain #2
Region A:
Residues: [74-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKLKGHKKKN QGQIKANRDR DTIVKLSSSV GETEEASTRD AISHDLERKD DVIEIATDTI  60
   61 NDATESPTQI PIDVNVVIKE TSTNNVAEGT ENVPPIKEST GIEVGNSPIT RRKKNKKKKT 120
  121 TNRRGRNSSN PADTTDLSKQ STLDSILVGI EEYLQEDGSK NEDIKVNIVQ DEPVNVEKMD 180
  181 IRTRNESSDK TFDIDVPNKD NVDETSSKSE NNINEEKAEH TLPREENEIL NVNEGNAASF 240
  241 KHQLEPHGLE AGDENGQAST KDVESESLTK NGFNFKENES KHLKAGEKQQ TESDRDGISP 300
  301 SVLAKNQKET EIGKEDHVFE QKDKEDEKCR KELSVNHENN MSHNFNAAGS DS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [426-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIPPETERET YDDETMGPTK RISDNEKNLQ HGTNDISVEV EKEEEEEEEE EENSTF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.358 a.4.5 "Winged helix" DNA-binding domain
View Download 0.401 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.552 a.30.1 ROP protein
View Download 0.436 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.354 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.314 a.4.5 "Winged helix" DNA-binding domain
View Download 0.310 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.288 a.46.1 Methionine synthase domain
View Download 0.282 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.266 a.2.7 tRNA-binding arm
View Download 0.261 a.4.5 "Winged helix" DNA-binding domain
View Download 0.243 a.2.3 Chaperone J-domain
View Download 0.231 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.205 a.4.1 Homeodomain-like

Predicted Domain #4
Region A:
Residues: [482-814]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKVKKENVTG EQEAVRNNEV SGTEEESTSK GEEIMGGDEK QSEAGEKSSI IEIEGSANSA  60
   61 KISKDNLVLE DEAEAPTQEN KPTEVVGEID IPDAPRDDVE IVEAVEKNII PEDLEVAKED 120
  121 QEGEQVKLDE PVKAMKDDKI AMRGAESISE DMKKKQEGTA ELSNEKAKKE VDETARESAE 180
  181 GVEVEKSKTP ESPKVVKRCT SGRPEDLQIN ERDPEVLKED VRVPDEDVKP EIATTIENSE 240
  241 EEDPKSQRVQ ISTEQAETTQ KDMGDVGSTT SFKEEEKPKR FEITQEGDKI TGKDTNHEHG 300
  301 EATEAASENS KASDVGTAEK YIEPSSESVK KDT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.21
Match: 1i3qA
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [815-917]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDAEVENSE KTEFIKVKAE LENLDAPKEA EVTAELNKEN EDVEVDTEED AEVENSEKTE  60
   61 FIKVKAELGN LDAPKEAEVT AELNKENEDV EVAATSKEDI ETK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.18
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #6
Region A:
Residues: [918-996]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CSEPAETPIE DGTCTEAEVS KKDAEAVTKE DENMENSKIA EALKDVTGDQ EIDDINISDE  60
   61 FQRTVELPEL EKQDIKDNK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.18
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #7
Region A:
Residues: [997-1066]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEDKELEVEE TEKETSLPDL VVEENITEEK NEIKQEEEEV SQLDFNETES ISKEAPNNDE  60
   61 NGFEDQSTRE 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.18
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #8
Region A:
Residues: [1067-1180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPKKASADDI FKDILDETNE FLEQLKIVDD SELNALLQSL DAKDSTTQTT EQSKKNNDKP  60
   61 QDVITTSEIR KLNEKEPVYI YTSLAGGGFH MIPRTNRLST ILTANRIPFT YRDL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.18
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #9
Region A:
Residues: [1181-1233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTDDEARKVW KTFSKGRSLP GVVRGHNDLI GNWEEIEEAN EDYKLRELIY DTI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.722 a.4.5 "Winged helix" DNA-binding domain
View Download 0.515 a.4.1 Homeodomain-like
View Download 0.528 d.186.1 Head-to-tail joining protein W, gpW
View Download 0.483 d.68.7 R3H domain
View Download 0.453 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.431 g.15.1 Ovomucoid/PCI-1 like inhibitors
View Download 0.430 a.64.2 Bacteriocin AS-48
View Download 0.422 a.60.1 SAM/Pointed domain
View Download 0.395 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.372 a.4.1 Homeodomain-like
View Download 0.367 a.140.1 LEM domain
View Download 0.333 a.4.1 Homeodomain-like
View Download 0.322 d.58.49 YajQ-like
View Download 0.317 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.303 g.58.1 Pheromone ER-23
View Download 0.299 a.65.1 Annexin
View Download 0.281 a.4.1 Homeodomain-like
View Download 0.277 a.4.5 "Winged helix" DNA-binding domain
View Download 0.272 a.64.1 Saposin
View Download 0.266 a.10.1 Protozoan pheromone proteins
View Download 0.259 a.156.1 S13-like H2TH domain
View Download 0.258 d.11.1 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
View Download 0.256 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.256 b.40.6 MOP-like
View Download 0.239 a.60.11 Hypothetical protein YjbJ
View Download 0.233 d.9.2 Description not found.
View Download 0.233 d.58.17 Metal-binding domain
View Download 0.231 g.34.1 HIV-1 VPU cytoplasmic domain
View Download 0.227 a.60.1 SAM/Pointed domain
View Download 0.214 d.58.17 Metal-binding domain
View Download 0.205 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle