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View Structure Prediction Details

Protein: AAD6
Organism: Saccharomyces cerevisiae
Length: 212 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AAD6.

Description E-value Query
Range
Subject
Range
GS69_BACSU - General stress protein 69 OS=Bacillus subtilis (strain 168) GN=yhdN PE=1 SV=2
GS69_BACSU - General stress protein 69 OS=Bacillus subtilis GN=yhdN PE=1 SV=2
gi|221322314 - gi|221322314|ref|ZP_03603608.1| hypothetical protein BsubsS_05312 [Bacillus subtilis subsp. subtilis...
gi|221318040 - gi|221318040|ref|ZP_03599334.1| hypothetical protein BsubsJ_05211 [Bacillus subtilis subsp. subtilis...
gi|221313116 - gi|221313116|ref|ZP_03594921.1| hypothetical protein BsubsN3_05267 [Bacillus subtilis subsp. subtili...
2.0E-56 [16..211] [1..181]
gi|126194344, gi... - gi|254240966|ref|ZP_04934288.1| hypothetical protein PA2G_01646 [Pseudomonas aeruginosa 2192], gi|19...
gi|11351605 - pir||H83328 probable oxidoreductase PA2535 [imported] - Pseudomonas aeruginosa (strain PAO1)
gi|218771712, gi... - gi|218891486|ref|YP_002440353.1| putative oxidoreductase [Pseudomonas aeruginosa LESB58], gi|2187717...
gi|15597731, gi|... - gi|9948592|gb|AAG05923.1|AE004681_5 probable oxidoreductase [Pseudomonas aeruginosa PAO1], gi|155977...
2.0E-56 [16..210] [1..181]
gi|29140683, gi|... - gi|29140683|ref|NP_804025.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica serov...
gi|16759133 - gi|16759133|ref|NP_454750.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica serov...
gi|213161253 - gi|213161253|ref|ZP_03346963.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica se...
gi|16501423, gi|... - gi|25316280|pir||AG0519 probable aldo/keto reductase STY0158 [imported] - Salmonella enterica subsp....
gi|213622060 - gi|213622060|ref|ZP_03374843.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica se...
gi|213585943 - gi|213585943|ref|ZP_03367769.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica se...
gi|213427399 - gi|213427399|ref|ZP_03360149.1| putative aldo/keto reductase [Salmonella enterica subsp. enterica se...
6.0E-56 [16..210] [1..180]
gi|25316293 - pir||C97390 aldo/keto reductase [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
gi|15155153, gi|... - gi|15887610|ref|NP_353291.1| hypothetical protein AGR_C_447 [Agrobacterium tumefaciens str. C58], gi...
4.0E-54 [14..210] [35..219]
gi|7471099 - pir||E75296 aldo/keto reductase - Deinococcus radiodurans (strain R1)
gi|15807252, gi|... - gi|6460065|gb|AAF11806.1|AE002058_6 aldo/keto reductase [Deinococcus radiodurans R1], gi|15807252|re...
6.0E-54 [18..210] [6..181]
gi|224501194 - gi|224501194|ref|ZP_03669501.1| hypothetical protein LmonFR_01515 [Listeria monocytogenes FSL R2-561...
gi|16804044 - gi|16804044|ref|NP_465529.1| hypothetical protein lmo2005 [Listeria monocytogenes EGD-e]
gi|255028145 - gi|255028145|ref|ZP_05300096.1| hypothetical protein LmonL_00759 [Listeria monocytogenes LO28]
gi|25316284, gi|... - pir||AE1325 oxidoreductase homolog lmo2005 [imported] - Listeria monocytogenes (strain EGD-e), gi|16...
gi|153196513, gi... - gi|254831753|ref|ZP_05236408.1| hypothetical protein Lmon1_10378 [Listeria monocytogenes 10403S], gi...
3.0E-53 [16..210] [1..191]
gi|25316285, gi|... - pir||AG1696 oxidoreductase homolog lin2113 [imported] - Listeria innocua (strain Clip11262), gi|1641...
gi|16801179 - gi|16801179|ref|NP_471447.1| hypothetical protein lin2113 [Listeria innocua Clip11262]
9.0E-53 [16..210] [1..191]
gi|162354048, gi... - gi|77636501|ref|ZP_00798574.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...
gi|153949015, gi... - gi|77632009|ref|ZP_00794595.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...
gi|229838380, gi... - gi|229838380|ref|ZP_04458539.1| putative aldo/keto reductase [Yersinia pestis biovar Orientalis str....
gi|229895886, gi... - gi|229895886|ref|ZP_04511056.1| putative aldo/keto reductase [Yersinia pestis Pestoides A], gi|22970...
gi|229898946, gi... - gi|229898946|ref|ZP_04514090.1| putative aldo/keto reductase [Yersinia pestis biovar Orientalis str....
gi|167423305, gi... - gi|167423305|ref|ZP_02315058.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar M...
Q66DJ3|Q66DJ3_YERPS - Putative aldo/keto reductase - Yersinia pseudotuberculosis
gi|167422517, gi... - gi|167422517|ref|ZP_02314270.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar O...
gi|169751829, gi... - gi|170025295|ref|YP_001721800.1| aldo/keto reductase [Yersinia pseudotuberculosis YPIII], gi|1697518...
gi|167467784 - gi|167467784|ref|ZP_02332488.1| putative aldo/keto reductase [Yersinia pestis FV-1]
gi|51588682, gi|... - gi|51595400|ref|YP_069591.1| putative aldo/keto reductase [Yersinia pseudotuberculosis IP 32953], gi...
gi|25316275 - pir||AI0341 probable aldo/keto reductase YPO2806 [imported] - Yersinia pestis (strain CO92)
gi|186894423, gi... - gi|186894423|ref|YP_001871535.1| aldo/keto reductase [Yersinia pseudotuberculosis PB1/+], gi|1866974...
gi|115348483, gi... - gi|218929872|ref|YP_002347747.1| putative aldo/keto reductase [Yersinia pestis CO92], gi|16123004|re...
gi|165914890, gi... - gi|89101578|ref|ZP_01174307.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...
gi|108808544, gi... - gi|108808544|ref|YP_652460.1| putative aldo/keto reductase [Yersinia pestis Antiqua], gi|108780457|g...
gi|229901431, gi... - gi|229901431|ref|ZP_04516553.1| putative aldo/keto reductase [Yersinia pestis Nepal516], gi|22968136...
gi|166008532, gi... - gi|166008532|ref|ZP_02229430.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar A...
gi|165925177, gi... - gi|165925177|ref|ZP_02221009.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar O...
gi|149365273, gi... - gi|149365273|ref|ZP_01887308.1| putative aldo/keto reductase [Yersinia pestis CA88-4125], gi|1492916...
gi|167051578, gi... - gi|167399074|ref|ZP_02304598.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar A...
gi|145599958, gi... - gi|145599958|ref|YP_001164034.1| aldo/keto reductase [Yersinia pestis Pestoides F], gi|145211654|gb|...
gi|166214570, gi... - gi|166214570|ref|ZP_02240605.1| oxidoreductase, aldo/keto reductase family [Yersinia pestis biovar A...
2.0E-52 [16..210] [1..180]
gi|13474214, gi|... - gi|14024966|dbj|BAB51568.1| oxidoreductase, aldo/keto reductase family [Mesorhizobium loti MAFF30309...
3.0E-52 [15..210] [1..183]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM SKERAFELLD  60
   61 AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI ATKFTTDYKK YDVGGGKSAN 120
  121 YCGNHKRSLH VSVRDSLRKL QTDWIDILYV HWWDYMSSIE EVMDSLHILV QQARSSIWVC 180
  181 LIRLPGLFLR QITTLNLMVK PLLASIKVNG TC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.201249
Match: 1exbA_
Description: Voltage-dependent K+ channel beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aldo-keto reductase activity 2.78826040220575 bayes_pls_golite062009
oxidoreductase activity 1.94013240130116 bayes_pls_golite062009
aldehyde reductase activity 1.71780727668617 bayes_pls_golite062009
catalytic activity 1.68179794468736 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.76912620964527 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.731893663103321 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle