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View Structure Prediction Details

Protein: YFL042C
Organism: Saccharomyces cerevisiae
Length: 674 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFL042C.

Description E-value Query
Range
Subject
Range
YHR080C - Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ...
LAM4_YEAST - Membrane-anchored lipid-binding protein LAM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
515.0 [0..7] [657..382]
gi|6330416 - gi|6330416|dbj|BAA86515.1| KIAA1201 protein [Homo sapiens]
479.0 [0..101] [623..17]
gi|73948510 - gi|73948510|ref|XP_541699.2| PREDICTED: similar to CG3304-PA, isoform A [Canis familiaris]
476.0 [0..85] [587..240]
gi|114640880 - gi|114640880|ref|XP_508832.2| PREDICTED: similar to GRAM domain containing 1B [Pan troglodytes]
472.0 [0..101] [623..144]
gi|109109066 - gi|109109066|ref|XP_001108370.1| PREDICTED: similar to CG3304-PA, isoform A isoform 1 [Macaca mulatt...
471.0 [0..109] [623..9]
gi|28972662 - gi|28972662|dbj|BAC65747.1| mKIAA1201 protein [Mus musculus]
468.0 [0..109] [623..24]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDVDNWEPV SDNEDSTDSV KQLGPPFEHA SNNDNAGDTE AESLQEVPLN TETNDVRKNL  60
   61 VVITNQSAAD EHPTEIKHDQ SRTSSTSSFF SGMISSFKSN VPSPVSRSTT PTSPVSQPSI 120
  121 ISHRREPSMG SKRRSSRRIS NATIAEIGSP LQQVEKPDEV KTRLTPSQMK EDNYDHRRFV 180
  181 EER

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.38
Match: 1h1kI
Description: THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [184-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YMDTPYHYAS EQRNKDFHET FKSVPKDDRL LDDFNCGLNR ELLYQGKLYI TETHLCFNSN  60
   61 VLGWIAKVLI AFEDVTFMEK TSAAGLFPSA ISIETKMGKT LFNGFISRDA AFGLMKEVWS 120
  121 RT

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 26.060481
Match: PF02893.11
Description: No description for PF02893.11 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.803 N/A N/A b.76.2 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain

Predicted Domain #3
Region A:
Residues: [306-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLQKDMASEN INTKAEKSGN GKEIDDAINS IDEENNDKDA NDNDTNENDD ENISTNETTP  60
   61 NSTSSSPDKE KEKAYKLRAD SSYQYDGPIY HHSTSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [402-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAEPMANNEF VLKELPFDCA PGILFEIMFN SEQNEFLLDF LRGQEGSQIT TIPNFTSIDG  60
   61 SSMTLKREYS YEKALHFPAG PKSTTCYVAE VIKRKDPDTY YEVISSIRTP NVPSGGSFST 120
  121 KTRYLIRWND EITCLLRVSF WVEWTGSSWI KGMVENGCKN GQLEAAQLME RILSKFIKNN 180
  181 VEECQITISK EEEE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.953
Match: 2pcsA
Description: No description for 2pcsA was found.

Predicted Domain #5
Region A:
Residues: [596-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDDKEVKNKL KEVDLEQPRE AVVTAPAIAE QQGLKVTMET WLFLYLIVVV LLLFNLFYIR  60
   61 SIAVSLHQLV KLQLVELKL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.906 a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle