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View Structure Prediction Details

Protein: BUR6
Organism: Saccharomyces cerevisiae
Length: 142 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUR6.

Description E-value Query
Range
Subject
Range
gi|7023238, gi|8... - gi|8922758|ref|NP_060737.1| H2A histone family, member J isoform 1 [Homo sapiens], gi|7023238|dbj|BA...
2.0E-39 [22..141] [1..114]
H2A2B_MOUSE - Histone H2A type 2-B OS=Mus musculus GN=Hist2h2ab PE=1 SV=3
9.0E-39 [22..141] [1..114]
gi|3745758, gi|3... - gi|3745762|pdb|1AOI|E Chain E, Complex Between Nucleosome Core Particle (H3,H4,H2a,H2b) And 146 Bp L...
2.0E-38 [32..141] [1..110]
H2A_ONCMY - Histone H2A OS=Oncorhynchus mykiss PE=1 SV=2
2.0E-38 [22..141] [1..114]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-38 [22..141] [1..114]
H2A_CAIMO - Histone H2A OS=Cairina moschata PE=3 SV=2
gi|224094529 - gi|224094529|ref|XP_002192812.1| PREDICTED: similar to Histone H2A [Taeniopygia guttata]
4.0E-38 [22..141] [1..114]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADQVPVTTQ LPPIKPEHEV PLDAGGSPVG NMGTNSNNNN ELGDVFDRIK THFPPAKVKK  60
   61 IMQTDEDIGK VSQATPVIAG RSLEFFIALL VKKSGEMARG QGTKRITAEI LKKTILNDEK 120
  121 FDFLREGLCV EEGQTQPEEE SA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.9794
Match: 1jfiA_
Description: Negative cofactor 2, NC2, alpha chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.28941584139552 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.99199798564473 bayes_pls_golite062009
transcription activator activity 2.58408368884371 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
transcription repressor activity 2.3574713307436 bayes_pls_golite062009
protein binding 2.1291876005999 bayes_pls_golite062009
transcription corepressor activity 1.30859203490073 bayes_pls_golite062009
sequence-specific DNA binding 1.18653213156155 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription coactivator activity 0.0885263144317296 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle