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View Structure Prediction Details

Protein: COM2
Organism: Saccharomyces cerevisiae
Length: 443 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COM2.

Description E-value Query
Range
Subject
Range
ZNF300 - zinc finger protein 300
gi|208968127 - gi|208968127|dbj|BAG73902.1| zinc finger protein 300 [synthetic construct]
0.0 [4..384] [179..600]
ZN252_CANLF - Zinc finger protein 252 OS=Canis lupus familiaris GN=ZNF252 PE=2 SV=1
0.0 [8..442] [381..816]
gi|15929737, gi|... - gi|21703954|ref|NP_663458.1| zinc finger protein 160 [Mus musculus], gi|15929737|gb|AAH15291.1| Zinc...
0.0 [7..442] [180..646]

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Predicted Domain #1
Region A:
Residues: [1-177]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLYPLQRFE SNDTVFSYTL NSKTELFNES RNNDKQHFTL QLIPNANANA KEIDNNNVEI  60
   61 INDLTGNTIV DNCVTTATSS NQLERRLSIS DYRTENGNYY EYEFFGRREL NEPLFNNDIV 120
  121 ENDDDIDLNN ESDVLMVSDD ELEVNERFSF LKQQPLDGLN RISSTNNLKN LEIHEFI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [178-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDPTENIDDE LEDSFTTVPQ SKKKVRDYFK LNIFGSSSSS NNNSNSLGCE PIQTENSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.035458
Match: 1a1iA_
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [236-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQKMFKNRFF RSRKSTLIKS LPLEQENEVL INSGFDVSSN EESDESDHAI INPLKLVGNN  60
   61 KDISTQSIAK TTNPFKSGSD FKMIEPVSKF SNDSRKDLLA AISEPSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.525 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.433 a.81.1 N-terminal domain of DnaB helicase
View Download 0.400 a.36.1 Signal peptide-binding domain
View Download 0.375 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.354 a.24.15 FAD-dependent thiol oxidase
View Download 0.343 a.1.1 Globin-like
View Download 0.302 d.41.2 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
View Download 0.302 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.280 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.265 a.74.1 Cyclin-like
View Download 0.233 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 f.14.1 Voltage-gated potassium channels

Predicted Domain #4
Region A:
Residues: [343-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSPSAPSPS VQSSSSSHGL VVRKKTGSMQ KTRGRKPSLI PDASKQFGCE FCDRRFKRQE  60
   61 HLKRHVRSLH MCEKPFTCHI CNKNFSRSDN LNQHVKTHAS L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.09691
Match: 2drpA_
Description: Tramtrack protein (two zinc-finger peptide)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle