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View Structure Prediction Details

Protein: YER077C
Organism: Saccharomyces cerevisiae
Length: 688 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YER077C.

Description E-value Query
Range
Subject
Range
gi|190405640 - gi|190405640|gb|EDV08907.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
MRX1_YEAST - MIOREX complex component 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRX1 PE=1 SV=...
YER077C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
0.0 [1..688] [1..688]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLKITKGQL RTKDLNQSSS KSSQSSRIGV DTCIFTRMLP RINTAINLTE HLLRRSFHSL  60
   61 TNLQKTQVKE RLHELERHGF ILNKTSKQLE RINSKKRRQL KKLQKTAYPK DQAFHILRKF 120
  121 HKINNEALAD TKLGP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.338 a.24.3 Cytochromes
View Download 0.394 f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.362 a.4.5 "Winged helix" DNA-binding domain
View Download 0.340 a.118.1 ARM repeat
View Download 0.432 a.24.1 Apolipoprotein
View Download 0.335 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.330 f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.303 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.300 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.298 a.118.8 TPR-like
View Download 0.297 a.63.1 Apolipophorin-III
View Download 0.282 a.118.8 TPR-like
View Download 0.280 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.279 a.2.7 tRNA-binding arm
View Download 0.269 a.2.7 tRNA-binding arm
View Download 0.268 a.1.1 Globin-like
View Download 0.268 a.24.9 alpha-catenin/vinculin
View Download 0.263 a.118.9 ENTH/VHS domain
View Download 0.262 d.109.1 Actin depolymerizing proteins
View Download 0.262 f.18.1 F1F0 ATP synthase subunit A
View Download 0.250 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.243 a.7.7 BAG domain
View Download 0.243 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.241 a.1.1 Globin-like
View Download 0.223 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.221 a.64.1 Saposin

Predicted Domain #2
Region A:
Residues: [136-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQSDLKFLS LTKDKRLFYT ILGVNGEQLR DSKLIANDVQ KFLKRGQLEK AVFLARLAKK  60
   61 KGVVGMNLIM KYYIEVVQSQ QSAVDIFNWR KKWGVPIDQH SITILFNGLS KQENLVSKKY 120
  121 GELVLKTIDS LCDKNELTEI EYNTA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.17
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [281-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAALINCTDE TLVFKLLNKK CPGLKKDSIT YTLMIRSCTR IADEKRFMVV LNDLMNKIPD  60
   61 YCVDSKLLFE YCEVICSQKS PKIEKQGMGL WALCEYFQFD KT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.17
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [383-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFKKYLTQSD FPTLVPLSHW NINKPFPLNK HVVGLFMNYC LKNKEYDLAM EIFKTLEAQN  60
   61 NQMLDQSIYH KYMETVITTR PITCGDECLD IYERVASSAQ ISITRRTLIL VYNAFQRQSL 120
  121 KAVINKDASN AEATLHKIRG FIDSVEATYS SKL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.17
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [536-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGKVYRFNSW KFLFPIVKNL NMNDKVSTVE LKSILDEYLK SLLNGEFGKE FKASIEDKRF  60
   61 VTLEGIRLVK VLTERIKLPS LDSEEIASLK GTERKKFLAR RHLLRLKQIL LEDLADIEGN 120
  121 SRRKGDSENT STSEERIMED LAELILETSY DKF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.249 a.39.1 EF-hand
View Download 0.315 a.22.1 Histone-fold
View Download 0.359 a.63.1 Apolipophorin-III
View Download 0.308 a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.249 a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.235 a.40.1 Calponin-homology domain, CH-domain
View Download 0.230 c.55.1 Actin-like ATPase domain
View Download 0.221 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.216 a.24.9 alpha-catenin/vinculin
View Download 0.213 a.22.1 Histone-fold
View Download 0.209 a.1.1 Globin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle