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View Structure Prediction Details

Protein: TDA2
Organism: Saccharomyces cerevisiae
Length: 126 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDA2.

Description E-value Query
Range
Subject
Range
TDA2 - Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytopla...
TDA2_YEAS2 - Topoisomerase I damage affected protein 2 OS=Saccharomyces cerevisiae (strain JAY291) GN=TDA2 PE=3 S...
TDA2_YEAST - Topoisomerase I damage affected protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
2.0E-62 [1..126] [1..126]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMQIEIKDG RSDNSPLPER KLVTLIQESY DSLKDDNEIN LSTESTSNLL IKLVLEKLEK  60
   61 HSSLYKYIAS VTTLNIEGLN EENANFSLKN DIGASWESKK DGIFNYKLED KNNNECYLIT 120
  121 ILWLHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.569 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.645 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.552 a.74.1 Cyclin-like
View Download 0.653 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.653 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.528 a.1.1 Globin-like
View Download 0.479 a.26.1 4-helical cytokines
View Download 0.463 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.456 c.53.1 Resolvase-like
View Download 0.445 a.2.3 Chaperone J-domain
View Download 0.443 d.164.1 SMAD MH1 domain
View Download 0.436 a.61.1 Retroviral matrix proteins
View Download 0.425 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.422 a.118.8 TPR-like
View Download 0.410 a.19.1 Fertilization protein
View Download 0.388 a.74.1 Cyclin-like
View Download 0.379 a.19.1 Fertilization protein
View Download 0.364 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.361 a.1.1 Globin-like
View Download 0.354 a.24.3 Cytochromes
View Download 0.349 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.342 a.47.2 t-snare proteins
View Download 0.339 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.337 a.1.1 Globin-like
View Download 0.335 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.330 d.21.1 Diaminopimelate epimerase-like
View Download 0.329 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.328 d.131.1 DNA clamp
View Download 0.320 a.118.9 ENTH/VHS domain
View Download 0.292 a.61.1 Retroviral matrix proteins
View Download 0.288 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.288 a.7.8 GAT domain
View Download 0.279 a.74.1 Cyclin-like
View Download 0.271 a.64.1 Saposin
View Download 0.265 d.8.1 Urease, gamma-subunit
View Download 0.265 a.118.11 Cytochrome c oxidase subunit E
View Download 0.261 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.257 a.72.1 Functional domain of the splicing factor Prp18
View Download 0.253 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.247 a.118.9 ENTH/VHS domain
View Download 0.239 a.24.17 Group V grass pollen allergen
View Download 0.239 a.118.9 ENTH/VHS domain
View Download 0.238 a.11.2 Second domain of FERM
View Download 0.233 a.4.5 "Winged helix" DNA-binding domain
View Download 0.232 a.118.9 ENTH/VHS domain
View Download 0.230 d.2.1 Lysozyme-like
View Download 0.227 d.8.1 Urease, gamma-subunit
View Download 0.227 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.227 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.223 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.220 a.39.1 EF-hand
View Download 0.218 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.214 a.126.1 Serum albumin-like
View Download 0.205 c.95.1 Thiolase-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle