YRC Public Data Repository - Protein Structure Prediction

Protein:	FCY22
Organism:	Saccharomyces cerevisiae
Length:	530 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FCY22.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-87	[1..530]	[1..528]
FCY22 - Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function FCY22_YEAST - Purine-cytosine permease FCY22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FCY22 PE=...	5.0E-87	[1..530]	[1..530]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	1.0E-74	[17..522]	[52..575]
gi\|165936285, gi... - gi\|89104688\|ref\|ZP_01177224.1\| COG0833: Amino acid transporters [Yersinia pestis biovar Orientalis s... gi\|108807022, gi... - gi\|108807022\|ref\|YP_650938.1\| lysine transporter [Yersinia pestis Antiqua], gi\|108778935\|gb\|ABG12993... gi\|229679023, gi... - gi\|229903253\|ref\|ZP_04518366.1\| lysine transporter [Yersinia pestis Nepal516], gi\|229679023\|gb\|EEO75... Q66CR2\|Q66CR2_YERPS - Lysine-specific permease lysP, APC family precursor - Yersinia pseudotuberculosis gi\|166009838, gi... - gi\|166009838\|ref\|ZP_02230736.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. E... gi\|165924474, gi... - gi\|165924474\|ref\|ZP_02220306.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|167400403, gi... - gi\|167400403\|ref\|ZP_02305916.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. U... gi\|166211768, gi... - gi\|166211768\|ref\|ZP_02237803.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. B... gi\|167424094, gi... - gi\|167424094\|ref\|ZP_02315847.1\| lysine-specific permease LysP [Yersinia pestis biovar Mediaevalis st... gi\|167419868, gi... - gi\|167419868\|ref\|ZP_02311621.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|186894753, gi... - gi\|186894753\|ref\|YP_001871865.1\| lysine transporter [Yersinia pseudotuberculosis PB1/+], gi\|18669777... gi\|170024977, gi... - gi\|170024977\|ref\|YP_001721482.1\| lysine transporter [Yersinia pseudotuberculosis YPIII], gi\|16975151... gi\|229841266, gi... - gi\|229841266\|ref\|ZP_04461425.1\| lysine transporter [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229843369, gi... - gi\|229843369\|ref\|ZP_04463515.1\| lysine transporter [Yersinia pestis biovar Orientalis str. India 195... gi\|229895742, gi... - gi\|229895742\|ref\|ZP_04510912.1\| lysine transporter [Yersinia pestis Pestoides A], gi\|229700665\|gb\|EE... gi\|149366712, gi... - gi\|149366712\|ref\|ZP_01888746.1\| putative lysine-specific permease [Yersinia pestis CA88-4125], gi\|14... gi\|145599660, gi... - gi\|145599660\|ref\|YP_001163736.1\| lysine transporter [Yersinia pestis Pestoides F], gi\|145211356\|gb\|A... gi\|25296480 - pir\|\|AH0159 probable lysine-specific permease lysP [imported] - Yersinia pestis (strain CO92) gi\|45435969, gi\|... - gi\|45441110\|ref\|NP_992649.1\| lysine transporter [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22126753, gi\|... - gi\|22126753\|ref\|NP_670176.1\| lysine transporter [Yersinia pestis KIM], gi\|21959776\|gb\|AAM86427.1\|AE0... gi\|218928459, gi... - gi\|218928459\|ref\|YP_002346334.1\| lysine transporter [Yersinia pestis CO92], gi\|16121591\|ref\|NP_40490... gi\|51595681, gi\|... - gi\|51595681\|ref\|YP_069872.1\| lysine transporter [Yersinia pseudotuberculosis IP 32953], gi\|51588963\|... gi\|162353225, gi... - gi\|77634357\|ref\|ZP_00796459.1\| COG0833: Amino acid transporters [Yersinia pestis Angola], gi\|1624204... gi\|153948146, gi... - gi\|77632298\|ref\|ZP_00794884.1\| COG0833: Amino acid transporters [Yersinia pseudotuberculosis IP 3175...	5.0E-74	[78..512]	[17..467]

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Predicted Domain #1

Region A:
Residues: [1-69]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEKLAMSMV DIKDAGSELR DLESGALDTK SSAADVYYEG VELHRTNEFI DNKPSFFNRI  60
   61 AAALNAETK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.829	a.159.2	FF domain

Predicted Domain #2

Region A:
Residues: [70-530]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIEPVTEDEK NDDSILNAAT IWFSANMVIV AYSVGALGPL VFGLNFGQSV LVIIFFNILG  60
   61 LIPVALFSLF GVELGLRQMI LSRYLAGNIT ARFFSLVNVI ACVGWCVLNI SVSAQLLNMV 120
  121 NEGSGHNCPI WAGCLIIAGG TVLVTFFGYS VVHAYEKWSW VPNFAAFLVI IAQLSRSGKF 180
  181 KGGEWVGGAT TAGGVLSFGS SVFGSAAGWA TYAADYTVYM PKTTSKYKIF FSVVAGLAFP 240
  241 LFFTMILGAA CGMAALNDPT WKSYYDKNAM GGVIYAILVP NSLNGFGQFC CVLLALSTVA 300
  301 NNVPGMYTVA LSAQALWAPL AKIPRVVWTM AGNAATLGIS IPATYYFDGF MENFMDSIGY 360
  361 YLAIYIAIAC SEHFIYRRSF SAYNIDDWDN WEHLPIGIAG TAALIAGAFG VALGMCQTYW 420
  421 VGEISRLIGE YGGDIGFELG GSWAFIIYNI VRPLELKYFG R

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	156.017729
Match:	PF02133
Description:	Permease for cytosine/purines, uracil, thiamine, allantoin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits