YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS1
Organism:	Saccharomyces cerevisiae
Length:	297 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS1.

Description	E-value	Query Range	Subject Range
gi\|168986284, gi... - gi\|168986343\|dbj\|BAG11882.1\| ATP phosphoribosyltransferase [Escherichia coli O55:H7], gi\|168986284\|d... HIS1_ECOHS - ATP phosphoribosyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=hisG PE=3 SV=1 gi\|168986400 - gi\|168986400\|dbj\|BAG11938.1\| ATP phosphoribosyltransferase [Escherichia coli O55:H6] HIS1_ECO24 - ATP phosphoribosyltransferase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=hisG PE=3 SV=1 HIS1_ECO27 - ATP phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=hisG PE=3 SV=1 HIS1_ECO8A - ATP phosphoribosyltransferase OS=Escherichia coli O8 (strain IAI1) GN=hisG PE=3 SV=1 gi\|237704476, gi... - gi\|237704476\|ref\|ZP_04534957.1\| ATP phosphoribosyltransferase [Escherichia sp. 3_2_53FAA], gi\|226900... HIS1_ECO45 - ATP phosphoribosyltransferase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=hisG PE=3 SV=1 HIS1_ECO55 - ATP phosphoribosyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=hisG PE=3 SV=1 gi\|194428767, gi... - gi\|194428767\|ref\|ZP_03061303.1\| ATP phosphoribosyltransferase [Escherichia coli B171], gi\|194413214\|... gi\|194431506, gi... - gi\|194431506\|ref\|ZP_03063798.1\| ATP phosphoribosyltransferase [Shigella dysenteriae 1012], gi\|194420... gi\|194424870, gi... - gi\|194436142\|ref\|ZP_03068244.1\| ATP phosphoribosyltransferase [Escherichia coli 101-1], gi\|194424870... HIS1_ECOBW - ATP phosphoribosyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=hisG PE=3 SV=1 HIS1_ECOSE - ATP phosphoribosyltransferase OS=Escherichia coli (strain SE11) GN=hisG PE=3 SV=1 HIS1_SHISS - ATP phosphoribosyltransferase OS=Shigella sonnei (strain Ss046) GN=hisG PE=3 SV=1 HIS1_ECOL6 - ATP phosphoribosyltransferase OS=Escherichia coli O6 GN=hisG PE=3 SV=1 HIS1_ECOLI - ATP phosphoribosyltransferase (EC 2.4.2.17) (ATP-PRTase) (ATP-PRT) - Escherichia coli EG10449 - ATP phosphoribosyltransferase / ATP-phosphoribosyltransferase HIS1_ECOLC - ATP phosphoribosyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=hisG PE=... sp\|B7UT56\|HIS1_ECO27 - ATP phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=hisG PE=3 SV=1 HIS1_SHIB3 - ATP phosphoribosyltransferase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=hisG PE... gi\|190909654, gi... - gi\|191170138\|ref\|ZP_03031692.1\| ATP phosphoribosyltransferase [Escherichia coli F11], gi\|190909654\|g... gi\|193062818, gi... - gi\|193062818\|ref\|ZP_03043911.1\| ATP phosphoribosyltransferase [Escherichia coli E22], gi\|192931461\|g... gi\|192955107, gi... - gi\|193071570\|ref\|ZP_03052478.1\| ATP phosphoribosyltransferase [Escherichia coli E110019], gi\|1929551... gi\|124530718, gi... - gi\|124530718\|ref\|ZP_01701275.1\| ATP phosphoribosyltransferase [Escherichia coli B], gi\|124499036\|gb\|... HIS1_ECOK1 - ATP phosphoribosyltransferase OS=Escherichia coli O1:K1 / APEC GN=hisG PE=3 SV=1 HIS1_ECODH - ATP phosphoribosyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=hisG PE=3 SV=1 HIS1_ECOSM - ATP phosphoribosyltransferase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=hisG PE=3 SV=1 gi\|1736697, gi\|8... - gi\|89108840\|ref\|AP_002620.1\| ATP phosphoribosyltransferase [Escherichia coli str. K-12 substr. W3110... HIS1_ECOL6 - ATP phosphoribosyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=hisG... HIS1_ECOUT - ATP phosphoribosyltransferase OS=Escherichia coli (strain UTI89 / UPEC) GN=hisG PE=3 SV=1 EG10449 - ATP phosphoribosyltransferase / ATP-phosphoribosyltransferase HIS1_ECOL5 - ATP phosphoribosyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=hisG PE=3 SV=1	0.0	[8..292]	[4..294]
HIS1_YARLI - ATP phosphoribosyltransferase OS=Yarrowia lipolytica GN=HIS1 PE=3 SV=1 HIS1_YARLI - ATP phosphoribosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HIS1 PE=3 SV=1	0.0	[1..297]	[1..296]
gi\|168751655, gi... - gi\|188014356\|gb\|EDU52478.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4113], gi... gi\|254793801, gi... - gi\|254793801\|ref\|YP_003078638.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. TW1435... gi\|15832074, gi\|... - gi\|15832074\|ref\|NP_310847.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. Sakai], gi... gi\|217329547, gi... - gi\|217329547\|ref\|ZP_03445626.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. TW14588... HIS1_ECO57 - ATP phosphoribosyltransferase OS=Escherichia coli O157:H7 GN=hisG PE=3 SV=1 gi\|208729034, gi... - gi\|208809233\|ref\|ZP_03251570.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4206]... gi\|208817178, gi... - gi\|208817178\|ref\|ZP_03258270.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4045]... gi\|208818490, gi... - gi\|208818490\|ref\|ZP_03258810.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4042]... HIS1_ECO5E - ATP phosphoribosyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=hisG PE=3 SV=1 gi\|189000125, gi... - gi\|189000125\|gb\|EDU69111.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4076], gi... gi\|189371603, gi... - gi\|189371603\|gb\|EDU90019.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|189378472, gi... - gi\|189378472\|gb\|EDU96888.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|195939357 - gi\|195939357\|ref\|ZP_03084739.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4024] gi\|12516200, gi\|... - gi\|15802498\|ref\|NP_288524.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 EDL933], gi\|125... gi\|168757561, gi... - gi\|189355459\|gb\|EDU73878.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4401], gi... gi\|25286968, gi\|... - pir\|\|B85827 ATP phosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|168764104, gi... - gi\|189365829\|gb\|EDU84245.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501], gi... gi\|189361200, gi... - gi\|189361200\|gb\|EDU79619.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4486], gi... gi\|168775535, gi... - gi\|187768985\|gb\|EDU32829.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4196], gi...	0.0	[8..292]	[4..294]
gi\|41708 - gi\|41708\|emb\|CAA31811.1\| unnamed protein product [Escherichia coli]	0.0	[8..292]	[4..294]
HIS1_SALPA - ATP phosphoribosyltransferase OS=Salmonella paratyphi A GN=hisG PE=3 SV=1 HIS1_SALTI - ATP phosphoribosyltransferase OS=Salmonella typhi GN=hisG PE=3 SV=1 HIS1_SALTI - ATP phosphoribosyltransferase OS=Salmonella typhi GN=hisG PE=3 SV=1 gi\|213648080 - gi\|213648080\|ref\|ZP_03378133.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALPA - ATP phosphoribosyltransferase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=hisG PE=3 SV=... gi\|29141302, gi\|... - gi\|29141302\|ref\|NP_804644.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|16761002 - gi\|16761002\|ref\|NP_456619.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|213161015 - gi\|213161015\|ref\|ZP_03346725.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213419233 - gi\|213419233\|ref\|ZP_03352299.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213425570 - gi\|213425570\|ref\|ZP_03358320.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213613119 - gi\|213613119\|ref\|ZP_03370945.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALPK - ATP phosphoribosyltransferase OS=Salmonella paratyphi A (strain AKU_12601) GN=hisG PE=3 SV=1 HIS1_SALDC - ATP phosphoribosyltransferase OS=Salmonella dublin (strain CT_02021853) GN=hisG PE=3 SV=1	0.0	[8..292]	[4..294]
HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis GN=hisG PE=3 SV=1 HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium GN=hisG PE=1 SV=1 HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis GN=hisG PE=3 SV=1 gi\|1045578, gi\|1... - gi\|1045581\|gb\|AAA80247.1\| ATP phosphoribosyltransferase, gi\|1045578\|gb\|AAA80244.1\| ATP phosphoribosy... gi\|1045587, gi\|1... - gi\|1045587\|gb\|AAA80252.1\| ATP phosphoribosyltransferase, gi\|1045584\|gb\|AAA80249.1\| ATP phosphoribosy... gi\|1045593, gi\|1... - gi\|1045593\|gb\|AAA80257.1\| ATP phosphoribosyltransferase, gi\|1045590\|gb\|AAA80254.1\| ATP phosphoribosy... gi\|1045599, gi\|1... - gi\|1045599\|gb\|AAA80262.1\| ATP phosphoribosyltransferase, gi\|1045596\|gb\|AAA80259.1\| ATP phosphoribosy... HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis (strain SC-B67) GN=hisG PE=3 SV=1 HIS1_SALPC - ATP phosphoribosyltransferase OS=Salmonella paratyphi C (strain RKS4594) GN=hisG PE=3 SV=1 lcl\|NC_016856.1_... - [gene=hisG] [protein=ATP phosphoribosyltransferase] [protein_id=YP_005238106.2] [location=2201167..2... HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=his... gi\|197265915, gi... - gi\|197265915\|ref\|ZP_03165989.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALHS - ATP phosphoribosyltransferase OS=Salmonella heidelberg (strain SL476) GN=hisG PE=3 SV=1 gi\|168466274, gi... - gi\|195631210\|gb\|EDX49770.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov... gi\|205338573, gi... - gi\|205338573\|gb\|EDZ25337.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov... HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium GN=hisG PE=1 SV=1 gi\|205330536, gi... - gi\|205330536\|gb\|EDZ17300.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov...	0.0	[8..292]	[4..294]
gi\|6478250 - gi\|6478250\|gb\|AAF13769.1\|AF129281_2 ATP phosphoribosyltransferase [Buchnera aphidicola] HIS1_BUCDN - ATP phosphoribosyltransferase OS=Buchnera aphidicola subsp. Diuraphis noxia GN=hisG PE=3 SV=1	0.0	[8..292]	[4..294]
HIS1_YERPN - ATP phosphoribosyltransferase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=hisG PE=3 SV=1 gi\|165923797, gi... - gi\|165924737\|ref\|ZP_02220569.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Orientalis str... HIS1_YERPS - ATP phosphoribosyltransferase OS=Yersinia pseudotuberculosis GN=hisG PE=3 SV=1 gi\|165939585, gi... - gi\|89105291\|ref\|ZP_01177813.1\| COG0040: ATP phosphoribosyltransferase [Yersinia pestis biovar Orient... gi\|166211282, gi... - gi\|166211282\|ref\|ZP_02237317.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Antiqua str. B... HIS1_YERPA - ATP phosphoribosyltransferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=hisG PE=3 SV=1 gi\|166009195, gi... - gi\|166009195\|ref\|ZP_02230093.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Antiqua str. E... gi\|21959497, gi\|... - gi\|22126500\|ref\|NP_669923.1\| ATP phosphoribosyltransferase [Yersinia pestis KIM], gi\|21959497\|gb\|AAM... HIS1_YERPS - ATP phosphoribosyltransferase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=hisG PE=... gi\|45436123, gi\|... - gi\|45441263\|ref\|NP_992802.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Microtus str. 910... gi\|149290844, gi... - gi\|149366470\|ref\|ZP_01888504.1\| ATP phosphoribosyltransferase [Yersinia pestis CA88-4125], gi\|149290... gi\|218928690, gi... - gi\|218928690\|ref\|YP_002346565.1\| ATP phosphoribosyltransferase [Yersinia pestis CO92], gi\|16121822\|r... HIS1_YERPP - ATP phosphoribosyltransferase OS=Yersinia pestis (strain Pestoides F) GN=hisG PE=3 SV=1 gi\|167421722, gi... - gi\|167421722\|ref\|ZP_02313475.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Orientalis str... gi\|167400242, gi... - gi\|167400242\|ref\|ZP_02305755.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Antiqua str. U... gi\|167469413 - gi\|167469413\|ref\|ZP_02334117.1\| ATP phosphoribosyltransferase [Yersinia pestis FV-1] gi\|167057192, gi... - gi\|167424343\|ref\|ZP_02316096.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Mediaevalis st... HIS1_YERPB - ATP phosphoribosyltransferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=hisG PE=3... HIS1_YERPY - ATP phosphoribosyltransferase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=hisG PE=... gi\|229841531, gi... - gi\|229841531\|ref\|ZP_04461690.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Orientalis str... HIS1_YERPE - ATP phosphoribosyltransferase OS=Yersinia pestis GN=hisG PE=3 SV=1 gi\|229843642, gi... - gi\|229843642\|ref\|ZP_04463785.1\| ATP phosphoribosyltransferase [Yersinia pestis biovar Orientalis str... gi\|229703654, gi... - gi\|229894256\|ref\|ZP_04509439.1\| ATP phosphoribosyltransferase [Yersinia pestis Pestoides A], gi\|2297... HIS1_YERPG - ATP phosphoribosyltransferase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=hisG PE=3 SV=1 HIS1_YERP3 - ATP phosphoribosyltransferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=hisG...	0.0	[10..292]	[6..294]
gi\|114846650 - gi\|114846650\|gb\|ABI82059.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-mRfp1] gi\|114846646 - gi\|114846646\|gb\|ABI82056.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-Gfp] gi\|114846328 - gi\|114846328\|gb\|ABI82045.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'] gi\|114846334 - gi\|114846334\|gb\|ABI82049.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-Cys] HIS1 - ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesi... gi\|114846331 - gi\|114846331\|gb\|ABI82047.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-His] gi\|114846642 - gi\|114846642\|gb\|ABI82053.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-FlagHis] HIS1_YEAST - ATP phosphoribosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HIS1 PE=1 ... gi\|114846639 - gi\|114846639\|gb\|ABI82051.1\| ATP phosphoribosyltransferase [Cloning vector pABC5'-HisCys]	0.0	[1..297]	[1..297]
HIS1_PASMU - ATP phosphoribosyltransferase OS=Pasteurella multocida (strain Pm70) GN=hisG PE=3 SV=1 HIS1_PASMU - ATP phosphoribosyltransferase OS=Pasteurella multocida GN=hisG PE=3 SV=1	0.0	[8..292]	[4..294]

Back

Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVNHLTDR LLFAIPKKGR LYSKSVSILN GADITFHRSQ RLDIALSTSL PVALVFLPAA  60
   61 DIPTFVGEGK CDLGITGVDQ VRESNVDVDL AIDLQFGNCK LQVQVPVNGE YKKPEQLIGK 120
  121 TIVTSFVKLA EKYFADLEGT TVEKMTTRIK FVSGSVEASC ALGIGDAIVD LVESGETMRA 180
  181 AGLVDIATVL STSAYLIESK NPKSDKSLIA TIKSRIEGVM TAQRFVSCIY NAPEDKLPEL 240
  241 LKV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	84.346787
Match:	PF01634
Description:	ATP phosphoribosyltransferase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [244-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPGRRAPTIS KIDDEGWVAV SSMIERKTKG VVLDELKRLG ASDIMVFEIS NCRV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits