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View Structure Prediction Details

Protein: GLN3
Organism: Saccharomyces cerevisiae
Length: 730 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLN3.

Description E-value Query
Range
Subject
Range
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
2.0E-73 [21..721] [113..823]
gi|171600 - gi|171600|gb|AAA34645.1| GLN3 protein
1.0E-71 [1..730] [1..730]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
8.0E-69 [189..719] [590..1124]
SPBPJ4664.02 - glycoprotein
YHU2_SCHPO - Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 OS=Schizosaccharomyces pombe (str...
1.0E-57 [9..719] [1837..2560]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-57 [8..716] [110..824]
MUC1 - mucin 1, cell surface associated
3.0E-57 [8..716] [110..824]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDDPENSKL YDLLNSHLDV HGRSNEEPRQ TGDSRSQSSG NTGENEEDIA FASGLNGGTF  60
   61 DSMLEALPDD LYFTDFVSPF TAAATTSVTT KTVKDTTPAT NHMDDDIAMF DSLATTQPID 120
  121 IAASNQQNGE IAQLWDFNVD QFNMTPSNSS GSATISAPNS FTSDIPQYNH GSLGNSVSKS 180
  181 SLFPYNSSTS NSNINQP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [198-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SINNNSNTNA QSHHSFNIYK LQNNNSSSSA MNITNNNNSN NSNIQHPFLK KSDSIGLSSS  60
   61 NTTNSVRKNS LIKPMSSTSL ANFK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.37734
Match: 1gnf__
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [282-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RAASVSSSIS NMEPSGQNKK PLIQCFNCKT FKTPLWRRSP EGNTLCNACG LFQKLHGTMR  60
   61 PLSLKSDVIK KRISKKRAKQ T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.383689
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription activator activity 2.9532663930699 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
sequence-specific DNA binding 2.72967350701574 bayes_pls_golite062009
protein binding 2.44501340584871 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.68943696300126 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
transcription repressor activity 0.256420113528322 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
structural constituent of ribosome 0.0613150171780344 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [363-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPNIAQNTPS APATASTSVT TTNAKPIRSR KKSLQQNSLS RVIPEEIIRD NIGNTNNILN  60
   61 VNRGGYNFNS VPSPVLMNSQ SYNSSNANFN GASNANLNSN NLMRHNSNTV TPNFRRSSRR 120
  121 SSTSSNTSSS SKSSSRSVVP ILPKPSPNSA NSQQFNMNMN LM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [525-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTNNVSAGN SVASSPRIIS SANFNSNSPL QQNLLSNSFQ RQGMNIPRRK MSRNASYSSS  60
   61 FMAASLQQLH EQQQVDVNSN TNTNSNRQNW NSSNSVSTNS RSSNFVSQKP NFDIFNTPVD 120
  121 SPSVSRPSSR KSHTSLLSQQ LQNSESNSFI SNHKFNNRLS SDSTSPIKYE ADVSAGGKIS 180
  181 EDNSTKGSSK ESSAIADELD WLKFGI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle